ENSDARG00000101510


Danio rerio

Features
Gene ID: ENSDARG00000101510
  
Biological name :cetn2
  
Synonyms : centrin, EF-hand protein, 2 / cetn2
  
Possible biological names infered from orthology : centrin 1 / centrin 2 / CETN1 / P41208 / P41209 / Q12798 / Q9R1K9
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 14662116
Gene end: 14666556
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000139580
NCBI entrez gene - 100006257     See in Manteia.
swissprot - A0A0R4IVN1
ZFIN ID - ZDB-GENE-091118-94
Ensembl - ENSDARG00000101510
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CETN2ENSGALG00000007510Gallus gallus
 CETN1ENSG00000177143Homo sapiens
 CETN2ENSG00000147400Homo sapiens
 Cetn1ENSMUSG00000050996Mus musculus
 Cetn2ENSMUSG00000031347Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cetn4 / centrin 4ENSDARG0000004121581
cetn3 / centrin 3 / O15182* / O35648*ENSDARG0000001182559
efcab2 / EF-hand calcium binding domain 2 / Q5VUJ9* / Q9CQ46* / EF-hand calcium-binding domain-containing protein 2 *ENSDARG0000007432326


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
SUMOylation of DNA damage response and repair proteins
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
DNA Damage Recognition in GG-NER
Formation of Incision Complex in GG-NER
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000019529 parp1 / poly (ADP-ribose) polymerase 1 / P09874* / poly (ADP-ribose) polymerase family, member 1*  / complex / reaction
 ENSDARG00000007438 ube2ib / Q9W6H5 / ubiquitin-conjugating enzyme E2Ib / UBE2I* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000028119 Q6NV25 / sumo3a / small ubiquitin-like modifier 3a / SUMO3* / Q9Z172* / P55854* / small ubiquitin-like modifier 3*  / complex / reaction
 ENSDARG00000035993 sumo3b / small ubiquitin-like modifier 3b / SUMO3* / P55854* / small ubiquitin-like modifier 3*  / complex / reaction
 ENSDARG00000044267 sumo1 / Q7SZR5 / small ubiquitin-like modifier 1 / P63166* / P63165* / Small ubiquitin-related modifier 1 *  / complex
 ENSDARG00000060510 cul4b / cullin 4B / A2A432* / Q13620*  / complex / reaction
 ENSDARG00000039754 xpc / xeroderma pigmentosum, complementation group C / P51612* / Q01831* / XPC complex subunit, DNA damage recognition and repair factor*  / complex / reaction
 ENSDARG00000038030 rbx1 / ring-box 1, E3 ubiquitin protein ligase / P62878* / P62877* / ring-box 1* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / complex / reaction
 ENSDARG00000041140 ddb2 / Q2YDS1 / damage-specific DNA binding protein 2 / Q92466* / Q99J79* / DNA damage-binding protein 2 *  / complex / reaction
 ENSDARG00000052649 Q9DDJ0 / ube2ia / ubiquitin-conjugating enzyme E2Ia / UBE2I* / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000021550 rad23b / RAD23 homolog B, nucleotide excision repair protein / P54727*  / complex / reaction
 ENSDARG00000096578 cul4a / cullin 4A / Q13619* / Q3TCH7*  / complex / reaction
 ENSDARG00000102741 sumo2b / Q6DHL4 / small ubiquitin-like modifier 2b / SUMO4* / SUMO2* / Q6EEV6* / P61956* / P61957* / small ubiquitin-like modifier 4* / small ubiquitin-like modifier 2*  / complex / reaction






 

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