ENSMUSG00000020265


Mus musculus

Features
Gene ID: ENSMUSG00000020265
  
Biological name :Sumo3
  
Synonyms : Q9Z172 / small ubiquitin-like modifier 3 / Sumo3
  
Possible biological names infered from orthology : P55854
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C1
Gene start: 77606097
Gene end: 77618331
  
Corresponding Affymetrix probe sets: 10364287 (MoGene1.0st)   1422457_s_at (Mouse Genome 430 2.0 Array)   1439372_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020501
Ensembl peptide - ENSMUSP00000134676
Ensembl peptide - ENSMUSP00000097136
Ensembl peptide - ENSMUSP00000133789
Ensembl peptide - ENSMUSP00000133466
Ensembl peptide - ENSMUSP00000133308
Ensembl peptide - ENSMUSP00000134416
NCBI entrez gene - 20610     See in Manteia.
MGI - MGI:1336201
RefSeq - NM_001301673
RefSeq - NM_001301671
RefSeq - NM_001301672
RefSeq - NM_019929
RefSeq Peptide - NP_001288600
RefSeq Peptide - NP_064313
RefSeq Peptide - NP_001288602
RefSeq Peptide - NP_001288601
swissprot - Q9Z172
swissprot - G3UWI9
swissprot - G3UWX9
swissprot - G3UXQ9
swissprot - G3UZA7
swissprot - G3UZX6
Ensembl - ENSMUSG00000020265
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6NV25ENSDARG00000028119Danio rerio
 sumo3bENSDARG00000035993Danio rerio
 SUMO3ENSGALG00000032783Gallus gallus
 SUMO3ENSG00000184900Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sumo2 / P61957 / small ubiquitin-like modifier 2ENSMUSG0000002073880
Sumo3ENSMUSG0000011224165
Sumo1 / P63166 / Small ubiquitin-related modifier 1 / P63165* / small ubiquitin-like modifier 1*ENSMUSG0000002602145


Protein motifs (from Interpro)
Interpro ID Name
 IPR000626  Ubiquitin domain
 IPR022617  Rad60/SUMO-like domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR033950  Sumo domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016925 protein sumoylation ISO
 biological_processGO:0034504 protein localization to nucleus IDA
 biological_processGO:0043392 negative regulation of DNA binding ISO
 biological_processGO:2000060 positive regulation of ubiquitin-dependent protein catabolic process IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0016605 PML body IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019789 SUMO transferase activity IDA
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0031386 protein tag IBA


Pathways (from Reactome)
Pathway description
SUMO is proteolytically processed
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription factors
SUMOylation of transcription cofactors
SUMOylation of intracellular receptors
SUMOylation of chromatin organization proteins
SUMOylation of DNA replication proteins
SUMOylation of immune response proteins
Formation of Incision Complex in GG-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000000751 Rpa1 / Q8VEE4 / Replication protein A 70 kDa DNA-binding subunit / P27694* / replication protein A1*  / reaction
 ENSMUSG00000002108 Nr1h3 / Q9Z0Y9 / Mus musculus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant 3, mRNA. / Q13133* / nuclear receptor subfamily 1 group H member 3*  / reaction
 ENSMUSG00000021144 Mta1 / Q8K4B0 / Mus musculus metastasis associated 1 (Mta1), transcript variant 2, mRNA. / Q13330* / metastasis associated 1*  / reaction
 ENSMUSG00000026313 Hdac4 / Q6NZM9 / Histone deacetylase 4 / P56524*  / reaction
 ENSMUSG00000017146 Brca1 / P48754 / Breast cancer type 1 susceptibility protein homolog / P38398* / BRCA1, DNA repair associated*  / reaction
 ENSMUSG00000020265 Sumo3 / Q9Z172 / small ubiquitin-like modifier 3 / P55854*  / - / reaction
 ENSMUSG00000020738 Sumo2 / P61957 / small ubiquitin-like modifier 2  / -
 ENSMUSG00000022809 Nr1i2 / O54915 / Nuclear receptor subfamily 1 group I member 2 / O75469*  / reaction
 ENSMUSG00000026496 Parp1 / poly (ADP-ribose) polymerase family, member 1 / P09874* / poly(ADP-ribose) polymerase 1*  / reaction
 ENSMUSG00000028426 P54728 / Rad23b / UV excision repair B / P54727* / RAD23 homolog B, nucleotide excision repair protein*  / complex
 ENSMUSG00000030094 Xpc / P51612 / xeroderma pigmentosum, complementation group C / Q01831* / XPC complex subunit, DNA damage recognition and repair factor*  / complex
 ENSMUSG00000020914 Top2a / Q01320 / DNA topoisomerase 2-alpha / P11388* / DNA topoisomerase II alpha*  / reaction
 ENSMUSG00000037373 Ctbp1 / O88712 / C-terminal-binding protein 1 / Q13363*  / reaction
 ENSMUSG00000060601 Nr1h2 / Q60644 / Oxysterols receptor LXR-beta / P55055* / nuclear receptor subfamily 1 group H member 2*  / reaction
 ENSMUSG00000034674 Tdg / P56581 / Mus musculus thymine DNA glycosylase (Tdg), transcript variant 3, mRNA. / Q13569* / thymine DNA glycosylase*  / reaction
 ENSMUSG00000060981 P62806 / Hist1h4h / Histone H4   / reaction
 ENSMUSG00000021779 Thrb / P37242 / Thyroid hormone receptor beta / P10828*  / reaction
 ENSMUSG00000022772 Senp5 / Q6NXL6 / Sentrin-specific protease 5 / Q96HI0* / SUMO1/sentrin specific peptidase 5*  / reaction
 ENSMUSG00000022855 Senp2 / Q91ZX6 / Mus musculus SUMO/sentrin specific peptidase 2 (Senp2), transcript variant 3, mRNA. / Q9HC62* / SUMO1/sentrin/SMT3 specific peptidase 2*  / reaction
 ENSMUSG00000024927 Rela / Q04207 / v-rel reticuloendotheliosis viral oncogene homolog A (avian) / Q04206* / RELA proto-oncogene, NF-kB subunit*  / reaction
 ENSMUSG00000038331 Satb2 / Q8VI24 / special AT-rich sequence binding protein 2 / Q9UPW6* / SATB homeobox 2*  / reaction
 ENSMUSG00000033075 Senp1 / P59110 / Sentrin-specific protease 1 / Q9P0U3* / SUMO1/sentrin specific peptidase 1*  / reaction
 ENSMUSG00000031347 Cetn2 / Q9R1K9 / Centrin-2 / P41208*  / complex / reaction
 ENSMUSG00000015120 Ube2i / P63280 / ubiquitin-conjugating enzyme E2I / P63279*  / complex / reaction
 ENSMUSG00000058756 Thra / P63058 / Thyroid hormone receptor alpha / P10827*  / reaction
 ENSMUSG00000030528 Blm / O88700 / Bloom syndrome protein homolog / P54132* / Bloom syndrome RecQ like helicase*  / reaction
 ENSMUSG00000071054 Safb / D3YXK2 / Scaffold attachment factor B1 / Q15424* / scaffold attachment factor B*  / reaction
 ENSMUSG00000036986 Pml / Q60953 / Protein PML / P29590* / promyelocytic leukemia*  / reaction
 ENSMUSG00000061607 Mdc1 / Q14676* / mediator of DNA damage checkpoint 1*  / reaction
 ENSMUSG00000023927 Satb1 / Q60611 / Mus musculus special AT-rich sequence binding protein 1 (Satb1), transcript variant 5, mRNA. / Q01826* / SATB homeobox 1*  / reaction






 

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