ENSMUSG00000026021


Mus musculus

Features
Gene ID: ENSMUSG00000026021
  
Biological name :Sumo1
  
Synonyms : P63166 / Small ubiquitin-related modifier 1 / Sumo1
  
Possible biological names infered from orthology : P63165 / small ubiquitin-like modifier 1
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: C2
Gene start: 59586558
Gene end: 59670834
  
Corresponding Affymetrix probe sets: 10355017 (MoGene1.0st)   10490078 (MoGene1.0st)   1438289_a_at (Mouse Genome 430 2.0 Array)   1451005_at (Mouse Genome 430 2.0 Array)   1456349_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000140729
Ensembl peptide - ENSMUSP00000088935
NCBI entrez gene - 22218     See in Manteia.
MGI - MGI:1197010
RefSeq - NM_009460
RefSeq Peptide - NP_033486
swissprot - A0A087WRQ4
swissprot - P63166
Ensembl - ENSMUSG00000026021
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sumo1ENSDARG00000044267Danio rerio
 SUMO1ENSGALG00000008435Gallus gallus
 SUMO1ENSG00000116030Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sumo3 / Q9Z172 / small ubiquitin-like modifier 3 / P55854*ENSMUSG0000002026550
Sumo2 / P61957 / small ubiquitin-like modifier 2ENSMUSG0000002073850
Sumo3ENSMUSG0000011224138


Protein motifs (from Interpro)
Interpro ID Name
 IPR000626  Ubiquitin domain
 IPR022617  Rad60/SUMO-like domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR033950  Sumo domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0016925 protein sumoylation ISO
 biological_processGO:0030578 PML body organization IMP
 biological_processGO:0031334 positive regulation of protein complex assembly IEA
 biological_processGO:0031647 regulation of protein stability IMP
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0034605 cellular response to heat IEA
 biological_processGO:0043392 negative regulation of DNA binding IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0045759 negative regulation of action potential IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0060021 roof of mouth development IMP
 biological_processGO:0071276 cellular response to cadmium ion IEA
 biological_processGO:0086004 regulation of cardiac muscle cell contraction IMP
 biological_processGO:0090204 protein localization to nuclear pore IMP
 biological_processGO:1901896 positive regulation of calcium-transporting ATPase activity IMP
 biological_processGO:1902260 negative regulation of delayed rectifier potassium channel activity IEA
 biological_processGO:1903169 regulation of calcium ion transmembrane transport IMP
 cellular_componentGO:0000792 heterochromatin IEA
 cellular_componentGO:0001650 fibrillar center IEA
 cellular_componentGO:0001741 XY body IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0016605 PML body ISS
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031510 SUMO activating enzyme complex IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0097165 nuclear stress granule IEA
 molecular_functionGO:0001222 transcription corepressor binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008134 transcription factor binding IMP
 molecular_functionGO:0015459 potassium channel regulator activity IEA
 molecular_functionGO:0019789 SUMO transferase activity ISO
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0030674 protein binding, bridging IEA
 molecular_functionGO:0031386 protein tag IBA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0035259 glucocorticoid receptor binding IEA
 molecular_functionGO:0044388 small protein activating enzyme binding IEA


Pathways (from Reactome)
Pathway description
SUMO is conjugated to E1 (UBA2:SAE1)
SUMO is transferred from E1 to E2 (UBE2I, UBC9)
SUMO is proteolytically processed
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription factors
SUMOylation of ubiquitinylation proteins
SUMOylation of transcription cofactors
SUMOylation of SUMOylation proteins
SUMOylation of intracellular receptors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA methylation proteins
SUMOylation of immune response proteins
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Formation of Incision Complex in GG-NER
G2/M DNA damage checkpoint
Regulation of IFNG signaling
Negative regulation of activity of TFAP2 (AP-2) family transcription factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gna13tm2.2Soff/Gna13tm2.2Soff,Tg(EIIa-cre)C5379Lmgd/?
Genetic Background: involves: FVB

Allelic Composition: Sumo1Gt(RRQ016)Byg/Sumo1Gt(RRQ016)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Sumo1tm1Oaj/Sumo1tm1Oaj
Genetic Background: involves: 129S7/SvEvBrd * ICR

Allelic Composition: Sumo1Gt(XA024)Byg/Sumo1Gt(XA024)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Sumo1tm1.1Bros/Sumo1tm1.1Bros
Genetic Background: involves: 129 * FVB/N

 MP:0008799 oblique facial cleft "presence of a facial fissure that runs from the lower lid edge to the lower edge of the nasal opening that results from a deficient fusion of the epithelium of the lacrimonasal duct" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gna13tm2.2Soff/Gna13tm2.2Soff,Tg(EIIa-cre)C5379Lmgd/?
Genetic Background: involves: FVB

 MP:0008886 abnormal PML bodies "alteration in structure, number or location of the subnuclear structures associated with functions including transcription, DNA repair, viral defense, stress, cell cycle regulation, proteolysis and apoptosis" [https://npd.hgu.mrc.ac.uk/compartments.html, MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Sumo1Gt(XA024)Byg/Sumo1Gt(XA024)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0009890 cleft secondary palate "congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722]
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Allelic Composition: Gna13tm2.2Soff/Gna13tm2.2Soff,Tg(EIIa-cre)C5379Lmgd/?
Genetic Background: involves: FVB

Allelic Composition: Eya1tm1Rilm/Eya1+,Sumo1Gt(RRQ016)Byg/Sumo1+
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Gna13tm2.2Soff/Gna13tm2.2Soff,Tg(EIIa-cre)C5379Lmgd/?
Genetic Background: involves: FVB

Allelic Composition: Sumo1Gt(RRQ016)Byg/Sumo1Gt(RRQ016)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0011109 partial lethality throughout fetal growth and development "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Gna13tm2.2Soff/Gna13tm2.2Soff,Tg(EIIa-cre)C5379Lmgd/?
Genetic Background: involves: FVB

Allelic Composition: Sumo1Gt(RRQ016)Byg/Sumo1Gt(RRQ016)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Rad9atm1.1(KOMP)Wtsi/Rad9atm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Rad9atm1.1(KOMP)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003099 Ppp5c / Q60676 / Serine/threonine-protein phosphatase 5 / P53041* / protein phosphatase 5 catalytic subunit*  / reaction
 ENSMUSG00000002221 Paxip1 / Q6NZQ4 / PAX-interacting protein 1 / Q6ZW49*  / complex / reaction
 ENSMUSG00000003226 Q9ERU9 / Ranbp2 / E3 SUMO-protein ligase RanBP2 / RGPD3* / RGPD2* / RGPD1* / RGPD8* / RGPD6* / RGPD5* / RGPD4* / A6NKT7* / O14715* / P0DJD0* / P0DJD1* / P49792* / Q7Z3J3* / Q99666* / RAN b...  / reaction / complex
 ENSMUSG00000004221 Ikbkg / O88522 / NF-kappa-B essential modulator / Q9Y6K9* / inhibitor of nuclear factor kappa B kinase subunit gamma*  / complex / reaction
 ENSMUSG00000004099 Dnmt1 / P13864 / DNA (cytosine-5)-methyltransferase 1 / P26358* / DNA methyltransferase 1*  / complex / reaction
 ENSMUSG00000004934 Pias4 / Q9JM05 / protein inhibitor of activated STAT 4 / Q8N2W9*  / complex / reaction
 ENSMUSG00000026313 Hdac4 / Q6NZM9 / Histone deacetylase 4 / P56524*  / complex / reaction
 ENSMUSG00000017146 Brca1 / P48754 / Breast cancer type 1 susceptibility protein homolog / P38398* / BRCA1, DNA repair associated*  / reaction / complex
 ENSMUSG00000020661 Dnmt3a / O88508 / DNA (cytosine-5)-methyltransferase 3A / Q9Y6K1* / DNA methyltransferase 3 alpha*  / complex / reaction
 ENSMUSG00000020184 Mdm2 / P23804 / E3 ubiquitin-protein ligase Mdm2 / Q00987* / MDM2 proto-oncogene*  / complex / reaction
 ENSMUSG00000017548 Suz12 / Q80U70 / Polycomb protein Suz12 / Q15022* / SUZ12 polycomb repressive complex 2 subunit*  / complex / reaction
 ENSMUSG00000020380 Rad50 / RAD50 double strand break repair protein / Q92878* / AC116366.3*  / complex / reaction
 ENSMUSG00000014074 Q80XJ2 / Rnf168 / E3 ubiquitin-protein ligase RNF168 / Q8IYW5* / ring finger protein 168*  / complex / reaction
 ENSMUSG00000019777 Hdac2 / histone deacetylase 2 / Q92769*  / complex / reaction
 ENSMUSG00000017485 Top2b / Q64511 / DNA topoisomerase 2-beta / Q02880* / DNA topoisomerase II beta*  / complex / reaction
 ENSMUSG00000021779 Thrb / P37242 / Thyroid hormone receptor beta / P10828*  / reaction / complex
 ENSMUSG00000022772 Senp5 / Q6NXL6 / Sentrin-specific protease 5 / Q96HI0* / SUMO1/sentrin specific peptidase 5*  / reaction
 ENSMUSG00000026398 Nr5a2 / P45448 / Nuclear receptor subfamily 5 group A member 2 / O00482*  / complex / reaction
 ENSMUSG00000022855 Senp2 / Q91ZX6 / Mus musculus SUMO/sentrin specific peptidase 2 (Senp2), transcript variant 3, mRNA. / Q9HC62* / SUMO1/sentrin/SMT3 specific peptidase 2*  / reaction
 ENSMUSG00000021615 Xrcc4 / X-ray repair complementing defective repair in Chinese hamster cells 4 / Q13426* / X-ray repair cross complementing 4*  / complex / reaction
 ENSMUSG00000026020 Nop58 / Q6DFW4 / Nucleolar protein 58 / Q9Y2X3* / NOP58 ribonucleoprotein*  / complex / reaction
 ENSMUSG00000026751 Nr5a1 / P33242 / Steroidogenic factor 1 / Q13285* / nuclear receptor subfamily 5 group A member 1*  / complex / reaction
 ENSMUSG00000024201 Kdm4b / Q91VY5 / Lysine-specific demethylase 4B / O94953* / lysine demethylase 4B*  / complex / reaction
 ENSMUSG00000090083 Rnf8 / Q8VC56 / E3 ubiquitin-protein ligase RNF8 / O76064* / ring finger protein 8*  / reaction / complex
 ENSMUSG00000026739 Bmi1 / P25916 / Polycomb complex protein BMI-1 / P35226* / COMMD3-BMI1* / COMMD3-BMI1 readthrough* / BMI1 proto-oncogene, polycomb ring finger*  / complex
 ENSMUSG00000039989 Cbx4 / O55187 / E3 SUMO-protein ligase CBX4 / O00257* / chromobox 4*  / complex
 ENSMUSG00000022314 Rad21 / Q61550 / Double-strand-break repair / O60216* / RAD21 cohesin complex component*  / complex
 ENSMUSG00000021025 Nfkbia / Q9Z1E3 / NF-kappa-B inhibitor alpha / P25963* / NFKB inhibitor alpha*  / complex / reaction
 ENSMUSG00000026496 Parp1 / poly (ADP-ribose) polymerase family, member 1 / P09874* / poly(ADP-ribose) polymerase 1*  / complex / reaction
 ENSMUSG00000028224 Nbn / Q9R207 / Nibrin / O60934*  / complex / reaction
 ENSMUSG00000035158 Mitf / Q08874 / melanogenesis associated transcription factor / O75030*  / reaction / complex
 ENSMUSG00000032238 Rora / P51448 / RAR-related orphan receptor alpha / P35398* / RAR related orphan receptor A*  / reaction / complex
 ENSMUSG00000033075 Senp1 / P59110 / Sentrin-specific protease 1 / Q9P0U3* / SUMO1/sentrin specific peptidase 1*  / reaction
 ENSMUSG00000031583 Wrn / O09053 / Werner syndrome RecQ like helicase / Q14191*  / complex
 ENSMUSG00000028640 Q61312 / Tfap2c / transcription factor AP-2, gamma / Q92754*  / complex / reaction
 ENSMUSG00000029167 O70343 / Ppargc1a / Peroxisome proliferator-activated receptor gamma coactivator 1-alpha / Q9UBK2* / PPARG coactivator 1 alpha*  / complex / reaction
 ENSMUSG00000033933 Vhl / P40338 / von Hippel-Lindau tumor suppressor / VHLL* / Q6RSH7* / P40337* / VHL like*  / complex / reaction
 ENSMUSG00000028964 Park7 / Q99LX0 / Protein/nucleic acid deglycase DJ-1 / Q99497* / Parkinsonism associated deglycase*  / complex / reaction
 ENSMUSG00000031347 Cetn2 / Q9R1K9 / Centrin-2 / P41208*  / complex
 ENSMUSG00000030166 Rad52 / P43352 / RAD52 homolog, DNA repair protein / P43351*  / complex / reaction
 ENSMUSG00000036822 Q80Z37 / Topors / E3 ubiquitin-protein ligase Topors / Q9NS56* / TOP1 binding arginine/serine rich protein*  / complex / reaction
 ENSMUSG00000031928 Mre11a / Q61216 / Double-strand break repair protein MRE11 / MRE11* / P49959* / MRE11 homolog, double strand break repair nuclease*  / complex / reaction
 ENSMUSG00000030094 Xpc / P51612 / xeroderma pigmentosum, complementation group C / Q01831* / XPC complex subunit, DNA damage recognition and repair factor*  / reaction / complex
 ENSMUSG00000027342 Pcna / P17918 / proliferating cell nuclear antigen / P12004*  / complex / reaction
 ENSMUSG00000042557 Sin3a / Q60520 / Mus musculus transcriptional regulator, SIN3A (yeast) (Sin3a), transcript variant 4, mRNA. / Q96ST3* / SIN3 transcription regulator family member A*  / complex / reaction
 ENSMUSG00000026222 Sp100 / O35892 / nuclear antigen Sp100 / Q9H930* / P23497* / SP140L* / SP100 nuclear antigen* / SP140 nuclear body protein like*  / reaction / complex
 ENSMUSG00000055065 Ddx17 / Q501J6 / Probable ATP-dependent RNA helicase DDX17 / Q92841* / DEAD-box helicase 17*  / complex / reaction
 ENSMUSG00000035234 Q8BPZ8 / Abraxas1 / BRCA1 A complex subunit / Q6UWZ7* / abraxas 1, BRCA1 A complex subunit*  / complex / reaction
 ENSMUSG00000043099 Hic1 / HIC ZBTB transcriptional repressor 1 / Q14526*  / complex / reaction
 ENSMUSG00000026648 Q8K4J0 / Dclre1c / Protein artemis / Q96SD1* / DNA cross-link repair 1C*  / complex / reaction
 ENSMUSG00000015120 Ube2i / P63280 / ubiquitin-conjugating enzyme E2I / P63279*  / complex / reaction
 ENSMUSG00000049932 H2afx / P27661 / Histone H2AX / P16104* / H2A histone family member X*  / complex / reaction
 ENSMUSG00000020914 Top2a / Q01320 / DNA topoisomerase 2-alpha / P11388* / DNA topoisomerase II alpha*  / reaction / complex
 ENSMUSG00000047638 Nr1h4 / Q60641 / Bile acid receptor / Q96RI1* / nuclear receptor subfamily 1 group H member 4*  / complex / reaction
 ENSMUSG00000048490 Nrip1 / Q8CBD1 / Mus musculus nuclear receptor interacting protein 1 (Nrip1), transcript variant 2, mRNA. / P48552* / nuclear receptor interacting protein 1*  / complex / reaction
 ENSMUSG00000058756 Thra / P63058 / Thyroid hormone receptor alpha / P10827*  / complex / reaction
 ENSMUSG00000027109 Sp3 / O70494 / Transcription factor Sp3 / Q02447* / Sp3 transcription factor*  / complex / reaction
 ENSMUSG00000042349 Ikbke / Q9R0T8 / Inhibitor of nuclear factor kappa-B kinase subunit epsilon / Q14164*  / complex / reaction
 ENSMUSG00000027478 Dnmt3b / O88509 / DNA (cytosine-5)-methyltransferase 3B / Q9UBC3* / DNA methyltransferase 3 beta*  / complex / reaction
 ENSMUSG00000033326 Kdm4a / Q8BW72 / Lysine-specific demethylase 4A / O75164* / AL451062.3* / lysine demethylase 4A*  / complex / reaction
 ENSMUSG00000050397 Foxl2 / O88470 / Forkhead box protein L2 / P58012* / forkhead box L2*  / complex / reaction
 ENSMUSG00000057406 Nsd2 / Q8BVE8 / Histone-lysine N-methyltransferase NSD2 / O96028* / nuclear receptor binding SET domain protein 2*  / complex / reaction
 ENSMUSG00000025862 Stag2 / O35638 / stromal antigen 2 / Q8N3U4*  / complex
 ENSMUSG00000022391 P46061 / Rangap1 / Ran GTPase-activating protein 1 / P46060*  / complex
 ENSMUSG00000019768 Esr1 / P19785 / Estrogen receptor / P03372* / estrogen receptor 1*  / complex / reaction
 ENSMUSG00000046532 Ar / P19091 / Androgen receptor / P10275*  / complex / reaction
 ENSMUSG00000055024 Ep300 / B2RWS6 / Histone acetyltransferase p300 / Q09472* / E1A binding protein p300*  / complex / reaction
 ENSMUSG00000029478 Ncor2 / Q9WU42 / Nuclear receptor corepressor 2 / Q9Y618*  / complex / reaction
 ENSMUSG00000022383 Ppara / P23204 / peroxisome proliferator activated receptor alpha / Q07869*  / complex / reaction
 ENSMUSG00000029521 Chek2 / Q9Z265 / Serine/threonine-protein kinase Chk2 / O96017* / checkpoint kinase 2*  / complex / reaction
 ENSMUSG00000031870 Pgr / Q00175 / Progesterone receptor / P06401*  / reaction / complex
 ENSMUSG00000061062 Gm10093 / HDAC1* / Q13547* / histone deacetylase 1*  / reaction / complex
 ENSMUSG00000037373 Ctbp1 / O88712 / C-terminal-binding protein 1 / Q13363*  / complex / reaction
 ENSMUSG00000030451 Herc2 / Q4U2R1 / E3 ubiquitin-protein ligase HERC2 / O95714* / HECT and RLD domain containing E3 ubiquitin protein ligase 2*  / complex / reaction
 ENSMUSG00000071054 Safb / D3YXK2 / Scaffold attachment factor B1 / Q15424* / scaffold attachment factor B*  / reaction / complex
 ENSMUSG00000020647 Ncoa1 / P70365 / Nuclear receptor coactivator 1 / Q15788*  / complex / reaction
 ENSMUSG00000052833 Sae1 / Q9R1T2 / SUMO-activating enzyme subunit 1 SUMO-activating enzyme subunit 1, N-terminally processed / Q9UBE0* / SUMO1 activating enzyme subunit 1*  / complex / reaction
 ENSMUSG00000036986 Pml / Q60953 / Protein PML / P29590* / promyelocytic leukemia*  / complex / reaction
 ENSMUSG00000002307 Daxx / Mus musculus Fas death domain-associated protein (Daxx), transcript variant 3, mRNA. / Q9UER7* / death domain associated protein*  / complex / reaction
 ENSMUSG00000061607 Mdc1 / Q14676* / mediator of DNA damage checkpoint 1*  / complex / reaction
 ENSMUSG00000015846 Rxra / P28700 / retinoid X receptor alpha / P19793*  / complex / reaction
 ENSMUSG00000025225 Nfkb2 / Q9WTK5 / nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 / Q00653* / nuclear factor kappa B subunit 2*  / reaction / complex
 ENSMUSG00000005897 Nr2c1 / Q505F1 / Nuclear receptor subfamily 2 group C member 1 / P13056*  / complex / reaction
 ENSMUSG00000034674 Tdg / P56581 / Mus musculus thymine DNA glycosylase (Tdg), transcript variant 3, mRNA. / Q13569* / thymine DNA glycosylase*  / complex / reaction
 ENSMUSG00000063049 Ing2 / Q9ESK4 / Inhibitor of growth protein 2 / Q9H160* / inhibitor of growth family member 2*  / complex / reaction
 ENSMUSG00000025878 Uimc1 / ubiquitin interaction motif containing 1 / Q96RL1*  / complex / reaction
 ENSMUSG00000027496 Aurka / P97477 / Aurora kinase A / O14965*  / complex
 ENSMUSG00000028426 P54728 / Rad23b / UV excision repair B / P54727* / RAD23 homolog B, nucleotide excision repair protein*  / complex
 ENSMUSG00000024561 Mbd1 / Mus musculus methyl-CpG binding domain protein 1 (Mbd1), transcript variant 4, mRNA. / Q9UIS9* / methyl-CpG binding domain protein 1*  / complex / reaction
 ENSMUSG00000022674 Q9D2M8 / Ube2v2 / ubiquitin-conjugating enzyme E2 variant 2 / Q15819* / ubiquitin conjugating enzyme E2 V2*  / complex
 ENSMUSG00000026021 Sumo1 / P63166 / Small ubiquitin-related modifier 1 / P63165* / small ubiquitin-like modifier 1*  / complex / reaction
 ENSMUSG00000009575 Cbx5 / Q61686 / Mus musculus chromobox 5 (Cbx5), transcript variant 4, mRNA. / P45973* / chromobox 5*  / complex / reaction
 ENSMUSG00000052997 Uba2 / Q9Z1F9 / ubiquitin-like modifier activating enzyme 2 / Q9UBT2*  / reaction / complex
 ENSMUSG00000032405 Pias1 / O88907 / protein inhibitor of activated STAT 1 / O75925*  / complex / reaction
 ENSMUSG00000060981 P62806 / Hist1h4h / Histone H4   / complex / reaction
 ENSMUSG00000028800 Hdac1 / O09106 / Histone deacetylase 1 / Q13547*  / complex / reaction
 ENSMUSG00000070544 Top1 / Q04750 / DNA topoisomerase 1 / P11387* / DNA topoisomerase I*  / reaction / complex
 ENSMUSG00000043909 P70399 / Trp53bp1 / TP53-binding protein 1 / Q12888* / TP53BP1* / tumor protein p53 binding protein 1*  / complex / reaction
 ENSMUSG00000036202 Rif1 / Q6PR54 / Telomere-associated protein RIF1 / Q5UIP0* / replication timing regulatory factor 1*  / reaction / complex
 ENSMUSG00000098374 Gm28043 / RNF8* / O76064* / ring finger protein 8*  / complex / reaction
 ENSMUSG00000042292 Mkl1 / Q8K4J6 / MKL/myocardin-like protein 1 / Q969V6* / megakaryoblastic leukemia (translocation) 1*  / complex / reaction
 ENSMUSG00000060373 Hnrnpc / Q9Z204 / Heteroous nuclear ribonucleoproteins C1/C2 / P07910* / heterogeneous nuclear ribonucleoprotein C (C1/C2)*  / complex / reaction
 ENSMUSG00000061436 Hipk2 / Q9QZR5 / homeodomain interacting protein kinase 2 / Q9H2X6*  / complex / reaction
 ENSMUSG00000024926 Kat5 / Q8CHK4 / Histone acetyltransferase KAT5 / Q92993* / lysine acetyltransferase 5*  / complex / reaction
 ENSMUSG00000034218 Atm / Q62388 / Serine-protein kinase ATM / Q13315* / ATM serine/threonine kinase*  / complex / reaction
 ENSMUSG00000023927 Satb1 / Q60611 / Mus musculus special AT-rich sequence binding protein 1 (Satb1), transcript variant 5, mRNA. / Q01826* / SATB homeobox 1*  / complex / reaction
 ENSMUSG00000094870 Q8K3J5 / Zfp131 / zinc finger protein 131 / P52739* / ZNF131*  / complex / reaction






 

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