ENSMUSG00000055065


Mus musculus

Features
Gene ID: ENSMUSG00000055065
  
Biological name :Ddx17
  
Synonyms : Ddx17 / Probable ATP-dependent RNA helicase DDX17 / Q501J6
  
Possible biological names infered from orthology : DEAD-box helicase 17 / Q92841
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: E1
Gene start: 79527736
Gene end: 79546741
  
Corresponding Affymetrix probe sets: 10430536 (MoGene1.0st)   1437773_x_at (Mouse Genome 430 2.0 Array)   1439037_at (Mouse Genome 430 2.0 Array)   1452155_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000055535
Ensembl peptide - ENSMUSP00000155307
Ensembl peptide - ENSMUSP00000155365
Ensembl peptide - ENSMUSP00000155737
NCBI entrez gene - 67040     See in Manteia.
MGI - MGI:1914290
RefSeq - NM_199079
RefSeq - NM_001040187
RefSeq - NM_199080
RefSeq Peptide - NP_001035277
RefSeq Peptide - NP_951061
RefSeq Peptide - NP_951062
swissprot - Q3TU25
swissprot - Q3U741
swissprot - Q501J6
Ensembl - ENSMUSG00000055065
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-156n14.5ENSDARG00000010873Danio rerio
 DDX17ENSGALG00000037360Gallus gallus
 DDX17ENSG00000100201Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ddx5 / Mus musculus DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 (Ddx5), transcript variant 3, mRNA. / P17844* / DEAD-box helicase 5*ENSMUSG0000002071965
Ddx42 / Q810A7 / ATP-dependent RNA helicase DDX42 / Q86XP3* / DEAD-box helicase 42*ENSMUSG0000002070536
Ddx43 / DEAD-box helicase 43 / Q9NXZ2*ENSMUSG0000007029132


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000380 alternative mRNA splicing, via spliceosome ISS
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome ISO
 biological_processGO:0001837 epithelial to mesenchymal transition ISO
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II ISS
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 biological_processGO:0010586 miRNA metabolic process ISO
 biological_processGO:0030520 intracellular estrogen receptor signaling pathway ISO
 biological_processGO:0030521 androgen receptor signaling pathway ISS
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0045445 myoblast differentiation IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0061614 pri-miRNA transcription by RNA polymerase II IMP
 biological_processGO:2001014 regulation of skeletal muscle cell differentiation ISS
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016607 nuclear speck ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003713 transcription coactivator activity ISO
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
SUMOylation of transcription cofactors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000015120 Ube2i / P63280 / ubiquitin-conjugating enzyme E2I / P63279*  / reaction
 ENSMUSG00000026021 Sumo1 / P63166 / Small ubiquitin-related modifier 1 / P63165* / small ubiquitin-like modifier 1*  / complex / reaction






 

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