ENSDARG00000024619


Danio rerio
domainfoxo6bdnabindingforkheadfoxoproteindna-templatedregulationrnapolymeraseiifactoractivitysequence-specificarsr-likehelix-turn-helixconservedsitetransactivationkix-bindinganatomicalstructuremorphogenesiscelldifferentiationnucleusdna-binding

Features
Gene ID: ENSDARG00000024619
  
Biological name :foxo6b
  
Synonyms : forkhead box O6 b / foxo6b
  
Possible biological names infered from orthology : A8MYZ6 / forkhead box O6 / Forkhead box protein O6 / FOXO6 / Q70KY4
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 15571290
Gene end: 15620967
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000107114
NCBI entrez gene - 566899     See in Manteia.
RefSeq - NM_001135132
RefSeq Peptide - NP_001128604
swissprot - F1R4K6
ZFIN ID - ZDB-GENE-060503-776
Ensembl - ENSDARG00000024619
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FOXO6ENSGALG00000026153Gallus gallus
 FOXO6ENSG00000204060Homo sapiens
 Foxo6ENSMUSG00000052135Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
foxo6a / forkhead box O6 a / FOXO6* / A8MYZ6* / Q70KY4* / forkhead box O6* / Forkhead box protein O6 *ENSDARG0000010048639
foxo3a / forkhead box O3A / FOXO3* / O43524* / Q9WVH4* / forkhead box O3* / Forkhead box protein O3 *ENSDARG0000002305834
foxo3b / forkhead box O3b / FOXO3* / O43524* / Q9WVH4* / forkhead box O3* / Forkhead box protein O3 *ENSDARG0000004290433
A3RK74 / foxo1a / forkhead box O1 a / FOXO1* / Q9R1E0* / Q12778* / forkhead box O1* / Forkhead box protein O1 *ENSDARG0000009955533
A3RK75 / foxo1b / forkhead box O1 b / FOXO1* / Q9R1E0* / Q12778* / forkhead box O1* / Forkhead box protein O1 *ENSDARG0000006154930
foxo4 / forkhead box O4 / P98177* / Q9WVH3* / Forkhead box protein O4 *ENSDARG0000005579227
foxm1 / forkhead box M1 / Q08050*ENSDARG0000000320012


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR030456  Fork head domain conserved site 2
 IPR032067  FOXO protein, transactivation domain
 IPR032068  FOXO protein, KIX-binding domain


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound menitrogen compound metabolic processbiosynthetic processbiosynthetic processcellular metabolic pcellular metabolic processprimary metabolic prprimary metabolic processorganic substance meorganic substance metabolic processanatomical structureanatomical structure developmentcellular developmentcellular developmental process
DNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityDNA-binding transcription factor activityorganic cyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingheterocyclic compound binding
cellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0030154 cell differentiation IBA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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