ENSDARG00000061549


Danio rerio

Features
Gene ID: ENSDARG00000061549
  
Biological name :foxo1b
  
Synonyms : A3RK75 / forkhead box O1 b / foxo1b
  
Possible biological names infered from orthology : forkhead box O1 / Forkhead box protein O1 / FOXO1 / Q12778 / Q9R1E0
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 31809226
Gene end: 31861474
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000082331
NCBI entrez gene - 567969     See in Manteia.
RefSeq - NM_001082857
RefSeq Peptide - NP_001076326
swissprot - A3RK75
ZFIN ID - ZDB-GENE-080425-3
Ensembl - ENSDARG00000061549
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FOXO1ENSGALG00000017034Gallus gallus
 FOXO1ENSG00000150907Homo sapiens
 Foxo1ENSMUSG00000044167Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A3RK74 / foxo1a / forkhead box O1 a / FOXO1* / Q9R1E0* / Q12778* / forkhead box O1* / Forkhead box protein O1 *ENSDARG0000009955563
foxo3b / forkhead box O3b / FOXO3* / O43524* / Q9WVH4* / forkhead box O3* / Forkhead box protein O3 *ENSDARG0000004290437
foxo3a / forkhead box O3A / FOXO3* / O43524* / Q9WVH4* / forkhead box O3* / Forkhead box protein O3 *ENSDARG0000002305836
foxo4 / forkhead box O4 / P98177* / Q9WVH3* / Forkhead box protein O4 *ENSDARG0000005579235
foxo6b / forkhead box O6 b / FOXO6* / A8MYZ6* / Q70KY4* / forkhead box O6* / Forkhead box protein O6 *ENSDARG0000002461934
foxo6a / forkhead box O6 a / FOXO6* / A8MYZ6* / Q70KY4* / forkhead box O6* / Forkhead box protein O6 *ENSDARG0000010048630
foxm1 / forkhead box M1 / Q08050*ENSDARG0000000320014


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR032067  FOXO protein, transactivation domain
 IPR032068  FOXO protein, KIX-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001945 lymph vessel development IGI
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0030154 cell differentiation IBA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
AKT phosphorylates targets in the nucleus
AKT-mediated inactivation of FOXO1A
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000028082 mapkapk5 / mitogen-activated protein kinase-activated protein kinase 5 / Q8IW41*  / reaction






 

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