ENSDARG00000030703


Danio rerio

Features
Gene ID: ENSDARG00000030703
  
Biological name :otx2a
  
Synonyms : orthodenticle homeobox 2a / otx2a / Q90267
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 50921266
Gene end: 50929957
  
Corresponding Affymetrix probe sets: Dr.5771.1.S1_at (Zebrafish Array)   NM_131215_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000013327
NCBI entrez gene - 30462     See in Manteia.
RefSeq - NM_131215
RefSeq Peptide - NP_571290
swissprot - Q90267
ZFIN ID - ZDB-GENE-980526-27
Ensembl - ENSDARG00000030703
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
otx1 / Q91994 / orthodenticle homeobox 1 / P32242* / P80205* / Homeobox protein OTX1 *ENSDARG0000009499267
otx2b / Q91981 / orthodenticle homeobox 2b / OTX2* / P32243* / orthodenticle homeobox 2*ENSDARG0000001123556
otx5 / orthodenticle homolog 5ENSDARG0000004348352
crx / cone-rod homeoboxENSDARG0000001198949
Q8JI10 / dmbx1a / diencephalon/mesencephalon homeobox 1a / DMBX1* / Q91ZK4* / Q8NFW5* / diencephalon/mesencephalon homeobox 1* / Diencephalon/mesencephalon homeobox protein 1 *ENSDARG0000000992221
dmbx1b / Q566X8 / diencephalon/mesencephalon homeobox 1b / DMBX1* / Q8NFW5* / diencephalon/mesencephalon homeobox 1*ENSDARG0000000251020
pitx3 / Q6QU75 / paired-like homeodomain 3ENSDARG0000007006919
pitx1 / paired-like homeodomain 1 / PITX3* / P78337* / O75364* / paired like homeodomain 3*ENSDARG0000011660818
pitx2 / Q9W5Z2 / paired-like homeodomain 2 / P97474* / Q99697* / paired-like homeodomain transcription factor 2*ENSDARG0000003619417
zgc:101100ENSDARG0000002195916
prrx1a / paired related homeobox 1a / PRRX1* / P63013* / P54821* / paired related homeobox 1* / Paired mesoderm homeobox protein 1 *ENSDARG0000003397116
prrx1b / paired related homeobox 1b / PRRX1* / P63013* / P54821* / paired related homeobox 1* / Paired mesoderm homeobox protein 1 *ENSDARG0000004202716
mixl1 / Mix paired-like homeobox / Q9H2W2* / Q9WUI0* / Homeobox protein MIXL1 *ENSDARG0000006925216
pax10 / paired box 10ENSDARG0000005336414
gsc / goosecoid / P56915* / Q02591* / goosecoid homeobox* / Homeobox protein goosecoid *ENSDARG0000005907313


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003025  Transcription factor Otx
 IPR009057  Homeobox-like domain superfamily
 IPR013851  Transcription factor Otx, C-terminal
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003406 retinal pigment epithelium development IGI
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0021549 cerebellum development IGI
 biological_processGO:0030901 midbrain development IGI
 biological_processGO:0030902 hindbrain development IGI
 biological_processGO:0030917 midbrain-hindbrain boundary development IGI
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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