ENSDARG00000032234


Danio rerio

Features
Gene ID: ENSDARG00000032234
  
Biological name :wnt2bb
  
Synonyms : wingless-type MMTV integration site family, member 2Bb / wnt2bb
  
Possible biological names infered from orthology : O70283 / Q93097 / wingless-type MMTV integration site family, member 2B / WNT2B / Wnt family member 2B
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 27743550
Gene end: 27768785
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000046003
NCBI entrez gene - 556087     See in Manteia.
RefSeq - NM_001044344
RefSeq Peptide - NP_001037809
swissprot - B0S7E3
ZFIN ID - ZDB-GENE-060824-6
Ensembl - ENSDARG00000032234
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WNT2BENSGALG00000034196Gallus gallus
 WNT2BENSG00000134245Homo sapiens
 Wnt2bENSMUSG00000027840Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
wnt2ba / wingless-type MMTV integration site family, member 2Ba / WNT2B* / Q93097* / Wnt family member 2B*ENSDARG0000000505073
wnt2 / Q92048 / wingless-type MMTV integration site family member 2 / P21552* / P09544* / Wnt family member 2*ENSDARG0000004111758
wnt5b / Q92050 / wingless-type MMTV integration site family, member 5b / Q9H1J7* / P22726* / Wnt family member 5B*ENSDARG0000010246444
wnt7bb / wingless-type MMTV integration site family, member 7Bb / WNT7B* / P56706* / P28047* / Wnt family member 7B* / wingless-type MMTV integration site family, member 7B*ENSDARG0000007110742
wnt7ab / wingless-type MMTV integration site family, member 7Ab / WNT7A* / O00755* / Wnt family member 7A*ENSDARG0000000248341
wnt7ba / wingless-type MMTV integration site family, member 7Ba / WNT7B* / P56706* / P28047* / Wnt family member 7B* / wingless-type MMTV integration site family, member 7B*ENSDARG0000002285841
wnt7aa / wingless-type MMTV integration site family, member 7Aa / WNT7A* / P24383* / O00755* / Wnt family member 7A* / wingless-type MMTV integration site family, member 7A*ENSDARG0000004482741
wnt5a / wingless-type MMTV integration site family, member 5a / P41221* / Wnt family member 5A*ENSDARG0000010497341
wnt4a / P47793 / wingless-type MMTV integration site family, member 4a / WNT4* / P56705* / P22724* / Wnt family member 4* / wingless-type MMTV integration site family, member 4*ENSDARG0000007120840
wnt4b / wingless-type MMTV integration site family, member 4bENSDARG0000004015938
wnt3 / wingless-type MMTV integration site family, member 3 / P17553* / P56703* / Wnt family member 3*ENSDARG0000003899037
wnt3a / wingless-type MMTV integration site family, member 3A / P56704* / Wnt family member 3A*ENSDARG0000005882237
wnt6b / wingless-type MMTV integration site family, member 6b / WNT6* / Q9Y6F9* / P22727* / Wnt family member 6* / wingless-type MMTV integration site family, member 6*ENSDARG0000007393536
wnt1 / P24257 / wingless-type MMTV integration site family, member 1 / P04628* / P04426* / Wnt family member 1*ENSDARG0000005555435
wnt16 / wingless-type MMTV integration site family, member 16 / Q9QYS1* / Q9UBV4* / Wnt family member 16*ENSDARG0000009497335
wnt11r / wingless-type MMTV integration site family, member 11, related / WNT11* / P48615* / O96014* / Wnt family member 11* / wingless-type MMTV integration site family, member 11*ENSDARG0000001479634
wnt11 / wingless-type MMTV integration site family, member 11ENSDARG0000000425632
wnt6a / wingless-type MMTV integration site family, member 6aENSDARG0000003828331


Protein motifs (from Interpro)
Interpro ID Name
 IPR005817  Wnt
 IPR009140  Wnt-2 protein
 IPR018161  Wnt protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IGI
 biological_processGO:0001889 liver development IMP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030182 neuron differentiation IBA
 biological_processGO:0031016 pancreas development IGI
 biological_processGO:0045165 cell fate commitment IBA
 biological_processGO:0048794 swim bladder development IMP
 biological_processGO:0061008 hepaticobiliary system development IGI
 biological_processGO:0061009 common bile duct development IMP
 biological_processGO:0061010 gall bladder development IMP
 biological_processGO:0061011 hepatic duct development IGI
 biological_processGO:0072574 hepatocyte proliferation IMP
 biological_processGO:2000056 regulation of Wnt signaling pathway involved in digestive tract morphogenesis IGI
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005109 frizzled binding IBA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000076 swim bladder swim bladder decreased size , abnormal
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 ZFA:0000123 liver liver decreased size , abnormal
liver quality , abnormal
liver aplastic , abnormal
liver hypoplastic , abnormal
liver absent , abnormal
liver morphology , abnormal
liver increased variability of size , abnormal
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 ZFA:0000140 pancreas pancreas decreased size , abnormal
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 ZFA:0000208 gall bladder gall bladder morphology , abnormal
gall bladder absent , abnormal
gall bladder decreased size , abnormal
gall bladder position , abnormal
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 ZFA:0001094 whole organism whole organism dead , abnormal
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 ZFA:0001114 head head morphology , abnormal
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 ZFA:0001115 trunk trunk morphology , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel decreased length , abnormal
intersegmental vessel absent , abnormal
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 ZFA:0005170 extrahepatic duct extrahepatic duct morphology , abnormal
extrahepatic duct decreased size , abnormal
extrahepatic duct absent , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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