ENSDARG00000071208


Danio rerio

Features
Gene ID: ENSDARG00000071208
  
Biological name :wnt4a
  
Synonyms : P47793 / wingless-type MMTV integration site family, member 4a / wnt4a
  
Possible biological names infered from orthology : P22724 / P56705 / wingless-type MMTV integration site family, member 4 / WNT4 / Wnt family member 4
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 39167846
Gene end: 39202915
  
Corresponding Affymetrix probe sets: Dr.385.1.S1_at (Zebrafish Array)   NM_001040387_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000095904
NCBI entrez gene - 30123     See in Manteia.
RefSeq - NM_001040387
RefSeq Peptide - NP_001035477
swissprot - P47793
swissprot - Q1RLW9
ZFIN ID - ZDB-GENE-980526-352
Ensembl - ENSDARG00000071208
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WNT4ENSGALG00000041708Gallus gallus
 WNT4ENSG00000162552Homo sapiens
 Wnt4ENSMUSG00000036856Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
wnt4b / wingless-type MMTV integration site family, member 4bENSDARG0000004015963
wnt5b / Q92050 / wingless-type MMTV integration site family, member 5b / Q9H1J7* / P22726* / Wnt family member 5B*ENSDARG0000010246447
wnt5a / wingless-type MMTV integration site family, member 5a / P41221* / Wnt family member 5A*ENSDARG0000010497347
wnt7ba / wingless-type MMTV integration site family, member 7Ba / WNT7B* / P56706* / P28047* / Wnt family member 7B* / wingless-type MMTV integration site family, member 7B*ENSDARG0000002285846
wnt2ba / wingless-type MMTV integration site family, member 2Ba / WNT2B* / Q93097* / Wnt family member 2B*ENSDARG0000000505045
wnt2bb / wingless-type MMTV integration site family, member 2Bb / WNT2B* / Q93097* / O70283* / Wnt family member 2B* / wingless-type MMTV integration site family, member 2B*ENSDARG0000003223445
wnt7aa / wingless-type MMTV integration site family, member 7Aa / WNT7A* / P24383* / O00755* / Wnt family member 7A* / wingless-type MMTV integration site family, member 7A*ENSDARG0000004482745
wnt7bb / wingless-type MMTV integration site family, member 7Bb / WNT7B* / P56706* / P28047* / Wnt family member 7B* / wingless-type MMTV integration site family, member 7B*ENSDARG0000007110745
wnt7ab / wingless-type MMTV integration site family, member 7Ab / WNT7A* / O00755* / Wnt family member 7A*ENSDARG0000000248343
wnt3 / wingless-type MMTV integration site family, member 3 / P17553* / P56703* / Wnt family member 3*ENSDARG0000003899043
wnt1 / P24257 / wingless-type MMTV integration site family, member 1 / P04628* / P04426* / Wnt family member 1*ENSDARG0000005555443
wnt3a / wingless-type MMTV integration site family, member 3A / P56704* / Wnt family member 3A*ENSDARG0000005882243
wnt6b / wingless-type MMTV integration site family, member 6b / WNT6* / Q9Y6F9* / P22727* / Wnt family member 6* / wingless-type MMTV integration site family, member 6*ENSDARG0000007393543
wnt2 / Q92048 / wingless-type MMTV integration site family member 2 / P21552* / P09544* / Wnt family member 2*ENSDARG0000004111742
wnt11r / wingless-type MMTV integration site family, member 11, related / WNT11* / P48615* / O96014* / Wnt family member 11* / wingless-type MMTV integration site family, member 11*ENSDARG0000001479639
wnt16 / wingless-type MMTV integration site family, member 16 / Q9QYS1* / Q9UBV4* / Wnt family member 16*ENSDARG0000009497339
wnt11 / wingless-type MMTV integration site family, member 11ENSDARG0000000425638
wnt6a / wingless-type MMTV integration site family, member 6aENSDARG0000003828338


Protein motifs (from Interpro)
Interpro ID Name
 IPR005817  Wnt
 IPR009142  Wnt-4 protein
 IPR018161  Wnt protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IMP
 biological_processGO:0007507 heart development IGI
 biological_processGO:0016055 Wnt signaling pathway IBA
 biological_processGO:0021986 habenula development IMP
 biological_processGO:0042074 cell migration involved in gastrulation IMP
 biological_processGO:0045165 cell fate commitment IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IPI
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:0048841 regulation of axon extension involved in axon guidance IMP
 biological_processGO:0070654 sensory epithelium regeneration IEP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005109 frizzled binding IBA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking
PCP/CE pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000359 habenular commissure habenular commissure aplastic , abnormal
habenular commissure decreased thickness , abnormal
habenular commissure discontinuous , abnormal
habenular commissure axon extension involved in axon guidance decreased process quality , abnormal
habenular commissure absent , abnormal
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 ZFA:0000360 heart tube heart tube bifurcated , abnormal
Show

 ZFA:0001094 whole organism whole organism has fewer parts of type pharyngeal pouch , abnormal
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 ZFA:0001106 pharyngeal pouch pharyngeal pouch malformed , abnormal
pharyngeal pouch cell migration increased speed , abnormal
pharyngeal pouch protein localization to plasma membrane decreased occurrence , abnormal
pharyngeal pouch endodermal cell elongated , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage malformed , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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