ENSDARG00000058822


Danio rerio

Features
Gene ID: ENSDARG00000058822
  
Biological name :wnt3a
  
Synonyms : wingless-type MMTV integration site family, member 3A / wnt3a
  
Possible biological names infered from orthology : P27467 / P56704 / Wnt family member 3A
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 3106237
Gene end: 3158919
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000089165
NCBI entrez gene - 60632     See in Manteia.
RefSeq - NM_001007185
RefSeq Peptide - NP_001007186
swissprot - F1QK98
ZFIN ID - ZDB-GENE-001106-1
Ensembl - ENSDARG00000058822
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WNT3AENSGALG00000042657Gallus gallus
 WNT3AENSG00000154342Homo sapiens
 Wnt3aENSMUSG00000009900Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
wnt3 / wingless-type MMTV integration site family, member 3 / P17553* / P56703* / Wnt family member 3*ENSDARG0000003899080
wnt5a / wingless-type MMTV integration site family, member 5a / P41221* / Wnt family member 5A*ENSDARG0000010497344
wnt7ba / wingless-type MMTV integration site family, member 7Ba / WNT7B* / P56706* / P28047* / Wnt family member 7B* / wingless-type MMTV integration site family, member 7B*ENSDARG0000002285843
wnt7bb / wingless-type MMTV integration site family, member 7Bb / WNT7B* / P56706* / P28047* / Wnt family member 7B* / wingless-type MMTV integration site family, member 7B*ENSDARG0000007110743
wnt5b / Q92050 / wingless-type MMTV integration site family, member 5b / Q9H1J7* / P22726* / Wnt family member 5B*ENSDARG0000010246443
wnt1 / P24257 / wingless-type MMTV integration site family, member 1 / P04628* / P04426* / Wnt family member 1*ENSDARG0000005555442
wnt4a / P47793 / wingless-type MMTV integration site family, member 4a / WNT4* / P56705* / P22724* / Wnt family member 4* / wingless-type MMTV integration site family, member 4*ENSDARG0000007120842
wnt7ab / wingless-type MMTV integration site family, member 7Ab / WNT7A* / O00755* / Wnt family member 7A*ENSDARG0000000248341
wnt2ba / wingless-type MMTV integration site family, member 2Ba / WNT2B* / Q93097* / Wnt family member 2B*ENSDARG0000000505041
wnt2bb / wingless-type MMTV integration site family, member 2Bb / WNT2B* / Q93097* / O70283* / Wnt family member 2B* / wingless-type MMTV integration site family, member 2B*ENSDARG0000003223441
wnt2 / Q92048 / wingless-type MMTV integration site family member 2 / P21552* / P09544* / Wnt family member 2*ENSDARG0000004111741
wnt7aa / wingless-type MMTV integration site family, member 7Aa / WNT7A* / P24383* / O00755* / Wnt family member 7A* / wingless-type MMTV integration site family, member 7A*ENSDARG0000004482741
wnt6b / wingless-type MMTV integration site family, member 6b / WNT6* / Q9Y6F9* / P22727* / Wnt family member 6* / wingless-type MMTV integration site family, member 6*ENSDARG0000007393541
wnt4b / wingless-type MMTV integration site family, member 4bENSDARG0000004015940
wnt16 / wingless-type MMTV integration site family, member 16 / Q9QYS1* / Q9UBV4* / Wnt family member 16*ENSDARG0000009497339
wnt11r / wingless-type MMTV integration site family, member 11, related / WNT11* / P48615* / O96014* / Wnt family member 11* / wingless-type MMTV integration site family, member 11*ENSDARG0000001479636
wnt11 / wingless-type MMTV integration site family, member 11ENSDARG0000000425635
wnt6a / wingless-type MMTV integration site family, member 6aENSDARG0000003828335


Protein motifs (from Interpro)
Interpro ID Name
 IPR005817  Wnt
 IPR009141  Wnt-3 protein
 IPR018161  Wnt protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001756 somitogenesis IMP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007498 mesoderm development IGI
 biological_processGO:0009880 embryonic pattern specification IGI
 biological_processGO:0009952 anterior/posterior pattern specification IGI
 biological_processGO:0009953 dorsal/ventral pattern formation IGI
 biological_processGO:0016055 Wnt signaling pathway IBA
 biological_processGO:0021794 thalamus development IGI
 biological_processGO:0030182 neuron differentiation IBA
 biological_processGO:0030903 notochord development IMP
 biological_processGO:0030917 midbrain-hindbrain boundary development IGI
 biological_processGO:0036342 post-anal tail morphogenesis IMP
 biological_processGO:0045165 cell fate commitment IBA
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:0060026 convergent extension IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005109 frizzled binding IBA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Regulation of FZD by ubiquitination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle cilium decreased length , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000077 tail bud tail bud morphology , abnormal
tail bud decreased length , abnormal
Show

 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton decreased size , abnormal
Show

 ZFA:0000114 heart heart decreased functionality , abnormal
Show

 ZFA:0000135 notochord notochord truncated , abnormal
Show

 ZFA:0000155 somite somite decreased amount , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
Show

 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
post-vent region curved ventral , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton aplastic , abnormal
Show

 ZFA:0001321 neurocranial trabecula neurocranial trabecula aplastic , abnormal
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 ZFA:0001405 ethmoid cartilage ethmoid cartilage aplastic , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage agenesis , abnormal
Show

 ZFA:0001613 pharyngeal arch 3-7 pharyngeal arch 3-7 morphology , abnormal
Show

 ZFA:0005004 aortic arch aortic arch morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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