ENSDARG00000034173


Danio rerio

Features
Gene ID: ENSDARG00000034173
  
Biological name :prkcq
  
Synonyms : prkcq / protein kinase C, theta
  
Possible biological names infered from orthology : Q02111 / Q04759
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 25410293
Gene end: 25441127
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000046252
Ensembl peptide - ENSDARP00000108813
Ensembl peptide - ENSDARP00000144017
NCBI entrez gene - 555521     See in Manteia.
RefSeq - NM_001089370
RefSeq Peptide - NP_001082839
swissprot - F1QTL5
swissprot - A3KP71
swissprot - F1R506
ZFIN ID - ZDB-GENE-041210-195
Ensembl - ENSDARG00000034173
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRKCQENSGALG00000034970Gallus gallus
 PRKCQENSG00000065675Homo sapiens
 PrkcqENSMUSG00000026778Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prkcdb / protein kinase C, delta b / PRKCD* / Q05655* / protein kinase C delta*ENSDARG0000007065162
prkcda / protein kinase C, delta a / PRKCD* / P28867* / Q05655* / protein kinase C delta*ENSDARG0000000920861
prkcha / protein kinase C, eta, a / PRKCH* / P24723* / P23298* / protein kinase C eta*ENSDARG0000001838241
prkcea / protein kinase C, epsilon a / PRKCE* / P16054* / Q02156* / protein kinase C epsilon*ENSDARG0000000300840
prkceb / protein kinase C, epsilon b / PRKCE* / P16054* / Q02156* / protein kinase C epsilon*ENSDARG0000006992840
prkchb / protein kinase C, eta, b / PRKCH* / P24723* / P23298* / protein kinase C eta*ENSDARG0000004324339
prkcbb / Q7SY24 / protein kinase C, beta b / PRKCB* / P05771* / protein kinase C beta*ENSDARG0000002225438
prkcba / protein kinase C, beta a / PRKCB* / P68404* / P05771* / protein kinase C beta*ENSDARG0000000872337
prkca / protein kinase C, alpha / P17252*ENSDARG0000011565737
prkcg / protein kinase C, gamma / P05129* / P63318*ENSDARG0000000456136
PRKCA / si:ch73-374l24.1 / si:ch1073-370j18.1 / P17252* / protein kinase C alpha*ENSDARG0000009984134
prkcz / protein kinase C, zeta / Q02956* / Q05513*ENSDARG0000004333229
prkci / Q90XF2 / protein kinase C, iota / P41743* / Q62074*ENSDARG0000002122528
akt2 / v-akt murine thymoma viral oncogene homolog 2 / P31751* / Q60823* / AKT serine/threonine kinase 2* / Mus musculus thymoma viral proto-onco 2 (Akt2), transcript variant 4, mRNA.*ENSDARG0000001121925
akt3b / v-akt murine thymoma viral oncogene homolog 3bENSDARG0000008720525
akt2l / v-akt murine thymoma viral oncogene homolog 2, like / AKT2* / P31751* / AKT serine/threonine kinase 2*ENSDARG0000010361225
akt3a / v-akt murine thymoma viral oncogene homolog 3a / AKT3* / Q9WUA6* / Q9Y243* / AKT serine/threonine kinase 3* / RAC-gamma serine/threonine-protein kinase *ENSDARG0000010481025
sgk3 / serum/glucocorticoid regulated kinase family, member 3 / Q96BR1* / Q9ERE3* / serum/glucocorticoid regulated kinase 3*ENSDARG0000006246023
sgk1 / Q7ZTW4 / serum/glucocorticoid regulated kinase 1 / Q9WVC6* / O00141* / Serine/threonine-protein kinase Sgk1 *ENSDARG0000002552222
si:ch211-195b13.1ENSDARG0000001662321


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR014376  Protein kinase C, delta/epsilon/eta/theta types
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal
 IPR020454  Diacylglycerol/phorbol-ester binding
 IPR034668  Novel protein kinase C theta, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 cellular_componentGO:0005622 intracellular IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0004697 protein kinase C activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Apoptotic cleavage of cellular proteins
Effects of PIP2 hydrolysis
Downstream TCR signaling
FCERI mediated NF-kB activation
Netrin-1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000018285 pdpk1b / 3-phosphoinositide dependent protein kinase 1b / PDPK1* / O15530* / Q9Z2A0* / 3-phosphoinositide dependent protein kinase 1*  / reaction
 ENSDARG00000028058 traf6 / Q6IWL4 / TNF receptor-associated factor 6 / P70196* / Q9Y4K3*  / complex / reaction
 ENSDARG00000021509 tab2 / Q5RFW2 / TGF-beta activated kinase 1/MAP3K7 binding protein 2 / Q9NYJ8* / Q99K90* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 *  / complex / reaction
 ENSDARG00000062063 tab3 / TGF-beta activated kinase 1/MAP3K7 binding protein 3 / Q571K4* / Q8N5C8* / TGF-beta activated kinase 1 and MAP3K7 binding protein 3*  / complex / reaction
 ENSDARG00000077130 bcl10 / B cell CLL/lymphoma 10 / O95999* / Q9Z0H7* / B-cell lymphoma/leukemia 10 *  / complex
 ENSDARG00000077768 malt1 / MALT paracaspase 1 / Q2TBA3* / Q9UDY8* / MALT1 paracaspase* / Mucosa-associated lymphoid tissue lymphoma translocation *  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr