ENSDARG00000077768


Danio rerio

Features
Gene ID: ENSDARG00000077768
  
Biological name :malt1
  
Synonyms : malt1 / MALT paracaspase 1
  
Possible biological names infered from orthology : MALT1 paracaspase / Mucosa-associated lymphoid tissue lymphoma translocation / Q2TBA3 / Q9UDY8
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 66310495
Gene end: 66340462
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000114608
Ensembl peptide - ENSDARP00000099992
Ensembl peptide - ENSDARP00000119194
swissprot - E7EZZ7
swissprot - E9QEU5
swissprot - F1R8W6
ZFIN ID - ZDB-GENE-070705-156
Ensembl - ENSDARG00000077768
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MALT1ENSGALG00000030063Gallus gallus
 MALT1ENSG00000172175Homo sapiens
 Malt1ENSMUSG00000032688Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
malt2 / MALT paracaspase 2ENSDARG0000000605243
malt3 / MALT paracaspase 3ENSDARG0000006815228


Protein motifs (from Interpro)
Interpro ID Name
 IPR001309  Peptidase C14, p20 domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR011029  Death-like domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR029030  Caspase-like domain superfamily
 IPR033540  Mucosa-associated lymphoid tissue lymphoma translocation protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA


Pathways (from Reactome)
Pathway description
Activation of NF-kappaB in B cells
Downstream TCR signaling
FCERI mediated NF-kB activation
CLEC7A (Dectin-1) signaling
CLEC7A/inflammasome pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000021509 tab2 / Q5RFW2 / TGF-beta activated kinase 1/MAP3K7 binding protein 2 / Q9NYJ8* / Q99K90* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 *  / complex / reaction
 ENSDARG00000028058 traf6 / Q6IWL4 / TNF receptor-associated factor 6 / P70196* / Q9Y4K3*  / complex / reaction
 ENSDARG00000034173 prkcq / protein kinase C, theta / Q02111* / Q04759*  / complex
 ENSDARG00000077130 bcl10 / B cell CLL/lymphoma 10 / O95999* / Q9Z0H7* / B-cell lymphoma/leukemia 10 *  / complex / reaction
 ENSDARG00000018285 pdpk1b / 3-phosphoinositide dependent protein kinase 1b / PDPK1* / O15530* / Q9Z2A0* / 3-phosphoinositide dependent protein kinase 1*  / complex / reaction
 ENSDARG00000008748 ube2na / ubiquitin-conjugating enzyme E2Na / UBE2N* / P61089* / UBE2NL* / P61088* / ubiquitin conjugating enzyme E2 N* / ubiquitin conjugating enzyme E2 N like (gene/pseudogene)*  / reaction
 ENSDARG00000062063 tab3 / TGF-beta activated kinase 1/MAP3K7 binding protein 3 / Q571K4* / Q8N5C8* / TGF-beta activated kinase 1 and MAP3K7 binding protein 3*  / complex / reaction
 ENSDARG00000045877 ube2nb / ubiquitin-conjugating enzyme E2Nb / UBE2N* / P61089* / UBE2NL* / P61088* / ubiquitin conjugating enzyme E2 N* / ubiquitin conjugating enzyme E2 N like (gene/pseudogene)*  / reaction
 ENSDARG00000067672 card9 / caspase recruitment domain family, member 9 / Q9H257*  / complex / reaction
 ENSDARG00000077768 malt1 / MALT paracaspase 1 / Q2TBA3* / Q9UDY8* / MALT1 paracaspase* / Mucosa-associated lymphoid tissue lymphoma translocation *  / - / complex / reaction






 

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