ENSGALG00000030063


Gallus gallus

Features
Gene ID: ENSGALG00000030063
  
Biological name :MALT1
  
Synonyms : MALT1 / MALT1 paracaspase
  
Possible biological names infered from orthology : Mucosa-associated lymphoid tissue lymphoma translocation / Q2TBA3 / Q9UDY8
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 808529
Gene end: 838934
  
Corresponding Affymetrix probe sets: Gga.14832.1.S1_at (Chicken Array)   GgaAffx.25664.1.S1_at (Chicken Array)   GgaAffx.25664.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046622
Ensembl peptide - ENSGALP00000049269
NCBI entrez gene - 426852     See in Manteia.
RefSeq - XM_003642904
RefSeq - XM_004949002
RefSeq - XM_004949003
RefSeq - XM_004949004
swissprot - A0A1D5P968
swissprot - A0A1D5P1T2
Ensembl - ENSGALG00000030063
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 malt1ENSDARG00000077768Danio rerio
 MALT1ENSG00000172175Homo sapiens
 Malt1ENSMUSG00000032688Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PCASP2 / paracaspase-2 ENSGALG0000002796146
ENSGALG0000004661114
ENSGALG0000003916411


Protein motifs (from Interpro)
Interpro ID Name
 IPR001309  Peptidase C14, p20 domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR011029  Death-like domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR029030  Caspase-like domain superfamily
 IPR033540  Mucosa-associated lymphoid tissue lymphoma translocation protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001923 B-1 B cell differentiation IEA
 biological_processGO:0002237 response to molecule of bacterial origin IEA
 biological_processGO:0002726 positive regulation of T cell cytokine production IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007250 activation of NF-kappaB-inducing kinase activity IEA
 biological_processGO:0009620 response to fungus IEA
 biological_processGO:0032743 positive regulation of interleukin-2 production IEA
 biological_processGO:0042098 T cell proliferation IEA
 biological_processGO:0042113 B cell activation IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050852 T cell receptor signaling pathway IEA
 biological_processGO:0050856 regulation of T cell receptor signaling pathway IEA
 biological_processGO:0050870 positive regulation of T cell activation IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0051168 nuclear export IEA
 biological_processGO:0051259 protein complex oligomerization IEA
 cellular_componentGO:0001650 fibrillar center IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0032449 CBM complex IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0019209 kinase activator activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0043621 protein self-association IEA
 molecular_functionGO:0089720 caspase binding IPI


Pathways (from Reactome)
Pathway description
Activation of NF-kappaB in B cells
Downstream TCR signaling
FCERI mediated NF-kB activation
CLEC7A (Dectin-1) signaling
CLEC7A/inflammasome pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004398 CARD11 / caspase recruitment domain family member 11 / Q8CIS0* / Q9BXL7* / Caspase recruitment domain-containing protein 11 *  / complex / reaction
 ENSGALG00000007932 TRAF6 / TNF receptor associated factor 6 / P70196* / Q9Y4K3*  / complex / reaction
 ENSGALG00000008015 UBE2V1 / ubiquitin-conjugating enzyme E2 variant 1 / Q13404* / ubiquitin conjugating enzyme E2 V1*  / reaction
 ENSGALG00000016284 TAB3 / TGF-beta activated kinase 1 and MAP3K7 binding protein 3 / Q571K4* / Q8N5C8* / TGF-beta activated kinase 1/MAP3K7 binding protein 3*  / complex / reaction
 ENSGALG00000012356 TAB2 / TGF-beta activated kinase 1/MAP3K7 binding protein 2 / Q99K90* / Q9NYJ8* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 *  / complex / reaction
 ENSGALG00000015596 MAP3K7 / mitogen-activated protein kinase kinase kinase 7 / O43318* / Q62073*  / complex / reaction
 ENSGALG00000012150 TAB1 / TGF-beta activated kinase 1 (MAP3K7) binding protein 1 / Q15750* / Q8CF89* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 *  / complex / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction
 ENSGALG00000028935 BCL10 / B cell CLL/lymphoma 10 / O95999* / Q9Z0H7* / B-cell lymphoma/leukemia 10 *  / complex / reaction
 ENSGALG00000034970 PRKCQ / protein kinase C theta / Q02111* / Q04759*  / complex
 ENSGALG00000006418 PDPK1 / 3-phosphoinositide dependent protein kinase 1 / O15530* / Q9Z2A0*  / complex / reaction
 ENSGALG00000030063 MALT1 / MALT1 paracaspase / Q2TBA3* / Q9UDY8* / Mucosa-associated lymphoid tissue lymphoma translocation *  / - / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction






 

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