ENSGALG00000012150


Gallus gallus

Features
Gene ID: ENSGALG00000012150
  
Biological name :TAB1
  
Synonyms : TAB1 / TGF-beta activated kinase 1 (MAP3K7) binding protein 1
  
Possible biological names infered from orthology : Q15750 / Q8CF89 / TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 50694466
Gene end: 50702940
  
Corresponding Affymetrix probe sets: GgaAffx.12424.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000019817
Ensembl peptide - ENSGALP00000061597
Ensembl peptide - ENSGALP00000060104
NCBI entrez gene - 418014     See in Manteia.
RefSeq - NM_001006240
RefSeq Peptide - NP_001006240
swissprot - A0A1L1RS11
swissprot - A0A1L1RMT9
swissprot - F1NEQ2
Ensembl - ENSGALG00000012150
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tab1ENSDARG00000036613Danio rerio
 TAB1ENSG00000100324Homo sapiens
 Tab1ENSMUSG00000022414Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001932  PPM-type phosphatase domain
 IPR015655  Protein phosphatase 2C family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000185 activation of MAPKKK activity IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0003007 heart morphogenesis IEA
 biological_processGO:0003279 cardiac septum development IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling IMP
 biological_processGO:0030324 lung development IEA
 biological_processGO:0035904 aorta development IEA
 biological_processGO:0050853 B cell receptor signaling pathway IMP
 biological_processGO:0060976 coronary vasculature development IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IEA
 molecular_functionGO:0019209 kinase activator activity IEA


Pathways (from Reactome)
Pathway description
NOD1/2 Signaling Pathway
FCERI mediated NF-kB activation
activated TAK1 mediates p38 MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
TNFR1-induced NFkappaB signaling pathway
CLEC7A (Dectin-1) signaling
Ub-specific processing proteases
Interleukin-1 signaling
IRAK2 mediated activation of TAK1 complex
TRAF6-mediated induction of TAK1 complex within TLR4 complex
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007932 TRAF6 / TNF receptor associated factor 6 / P70196* / Q9Y4K3*  / complex / reaction
 ENSGALG00000008015 UBE2V1 / ubiquitin-conjugating enzyme E2 variant 1 / Q13404* / ubiquitin conjugating enzyme E2 V1*  / complex
 ENSGALG00000016284 TAB3 / TGF-beta activated kinase 1 and MAP3K7 binding protein 3 / Q571K4* / Q8N5C8* / TGF-beta activated kinase 1/MAP3K7 binding protein 3*  / complex / reaction
 ENSGALG00000008407 IRAK2 / interleukin-1 receptor-associated kinase-like 2 / O43187* / Q8CFA1* / interleukin 1 receptor associated kinase 2*  / complex / reaction
 ENSGALG00000012356 TAB2 / TGF-beta activated kinase 1/MAP3K7 binding protein 2 / Q99K90* / Q9NYJ8* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 *  / complex / reaction
 ENSGALG00000015596 MAP3K7 / mitogen-activated protein kinase kinase kinase 7 / O43318* / Q62073*  / complex / reaction
 ENSGALG00000004398 CARD11 / caspase recruitment domain family member 11 / Q8CIS0* / Q9BXL7* / Caspase recruitment domain-containing protein 11 *  / complex / reaction
 ENSGALG00000013057 USP41* / USP18* / Q9WTV6* / Q3LFD5* / Q9UMW8* / ubiquitin specific peptidase 18* / ubiquitin specific peptidase 41*  / complex
 ENSGALG00000012150 TAB1 / TGF-beta activated kinase 1 (MAP3K7) binding protein 1 / Q15750* / Q8CF89* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 *  / complex / reaction
 ENSGALG00000026850 TICAM1 / TIR domain-containing adapter molecule 1 / Q80UF7* / Q8IUC6* / toll like receptor adaptor molecule 1*  / complex / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex / reaction
 ENSGALG00000043535 RIPK2 / receptor-interacting serine/threonine-protein kinase 2 / O43353* / P58801* / receptor interacting serine/threonine kinase 2* / receptor (TNFRSF)-interacting serine-threonine kinase 2*  / complex / reaction
 ENSGALG00000028935 BCL10 / B cell CLL/lymphoma 10 / O95999* / Q9Z0H7* / B-cell lymphoma/leukemia 10 *  / complex / reaction
 ENSGALG00000034970 PRKCQ / protein kinase C theta / Q02111* / Q04759*  / complex / reaction
 ENSGALG00000030063 MALT1 / MALT1 paracaspase / Q2TBA3* / Q9UDY8* / Mucosa-associated lymphoid tissue lymphoma translocation *  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex / reaction
 ENSGALG00000039140 CD14 / monocyte differentiation antigen CD14 precursor / P10810* / P08571* / CD14 molecule* / Monocyte differentiation antigen CD14 *  / complex / reaction
 ENSGALG00000032701 LY96 / lymphocyte antigen 96 / Q9JHF9* / Q9Y6Y9*  / complex / reaction
 ENSGALG00000036807 NOD1 / Gallus gallus nucleotide binding oligomerization domain containing 1 (NOD1), mRNA. / Q8BHB0* / Q9Y239* / nucleotide binding oligomerization domain containing 1* / Nucleotide-binding ...  / complex / reaction






 

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