ENSGALG00000008015


Gallus gallus

Features
Gene ID: ENSGALG00000008015
  
Biological name :UBE2V1
  
Synonyms : UBE2V1 / ubiquitin-conjugating enzyme E2 variant 1
  
Possible biological names infered from orthology : Q13404 / ubiquitin conjugating enzyme E2 V1
  
Species: Gallus gallus
  
Chr. number: 20
Strand: 1
Band:
Gene start: 13956578
Gene end: 13970798
  
Corresponding Affymetrix probe sets: Gga.4159.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012992
Ensembl peptide - ENSGALP00000061904
Ensembl peptide - ENSGALP00000055302
Ensembl peptide - ENSGALP00000050645
NCBI entrez gene - 100538349     See in Manteia.
RefSeq - XM_015296315
RefSeq - NM_001205097
RefSeq - XM_015296313
RefSeq - XM_015296314
RefSeq Peptide - NP_001192026
swissprot - A0A1L1RSW4
swissprot - A0A1I7Q403
swissprot - A0A1D5PQY1
swissprot - A0A1D5PD04
Ensembl - ENSGALG00000008015
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ube2v1ENSDARG00000041875Danio rerio
 Q13404ENSG00000244687Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UBE2V2 / Q5F3Z3 / Ubiquitin-conjugating enzyme E2 variant 2 / Q9D2M8* / Q15819* / ubiquitin conjugating enzyme E2 V2*ENSGALG0000002813383


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0070534 protein K63-linked ubiquitination IEA
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031371 ubiquitin conjugating enzyme complex IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0035370 UBC13-UEV1A complex IEA


Pathways (from Reactome)
Pathway description
Downstream TCR signaling
FCERI mediated NF-kB activation
activated TAK1 mediates p38 MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
CLEC7A (Dectin-1) signaling
Interleukin-1 signaling
IKK complex recruitment mediated by RIP1
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007932 TRAF6 / TNF receptor associated factor 6 / P70196* / Q9Y4K3*  / complex / reaction
 ENSGALG00000004398 CARD11 / caspase recruitment domain family member 11 / Q8CIS0* / Q9BXL7* / Caspase recruitment domain-containing protein 11 *  / reaction
 ENSGALG00000006418 PDPK1 / 3-phosphoinositide dependent protein kinase 1 / O15530* / Q9Z2A0*  / reaction
 ENSGALG00000008015 UBE2V1 / ubiquitin-conjugating enzyme E2 variant 1 / Q13404* / ubiquitin conjugating enzyme E2 V1*  / complex / reaction
 ENSGALG00000016284 TAB3 / TGF-beta activated kinase 1 and MAP3K7 binding protein 3 / Q571K4* / Q8N5C8* / TGF-beta activated kinase 1/MAP3K7 binding protein 3*  / complex
 ENSGALG00000012356 TAB2 / TGF-beta activated kinase 1/MAP3K7 binding protein 2 / Q99K90* / Q9NYJ8* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 *  / complex
 ENSGALG00000015596 MAP3K7 / mitogen-activated protein kinase kinase kinase 7 / O43318* / Q62073*  / complex
 ENSGALG00000016590 TLR7 / toll-like receptor 7 / P58681* / Q9NYK1*  / reaction
 ENSGALG00000012150 TAB1 / TGF-beta activated kinase 1 (MAP3K7) binding protein 1 / Q15750* / Q8CF89* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 *  / complex
 ENSGALG00000012124 PELI2 / pellino E3 ubiquitin protein ligase family member 2 / Q9HAT8*  / complex
 ENSGALG00000009586 IRAK4 / interleukin-1 receptor-associated kinase 4 / Q8R4K2* / Q9NWZ3*  / complex / reaction
 ENSGALG00000028935 BCL10 / B cell CLL/lymphoma 10 / O95999* / Q9Z0H7* / B-cell lymphoma/leukemia 10 *  / reaction
 ENSGALG00000005947 MYD88 / A5HNF6 / Myeloid differentiation primary response protein MyD88 / Q99836* / P22366* / myeloid differentiation primary response 88* / myeloid differentiation primary response gene 88*  / reaction
 ENSGALG00000008837 PELI1 / E3 ubiquitin-protein ligase pellino homolog 1 / Q8C669* / Q96FA3* / pellino 1* / pellino E3 ubiquitin protein ligase 1*  / complex
 ENSGALG00000030063 MALT1 / MALT1 paracaspase / Q2TBA3* / Q9UDY8* / Mucosa-associated lymphoid tissue lymphoma translocation *  / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr