ENSDARG00000042861
Danio rerio | |
Features
| Gene ID: | ENSDARG00000042861 | | | | | Biological name : | ltk | | | | | Synonyms : | leukocyte receptor tyrosine kinase / ltk | | | | | Possible biological names infered from orthology : | Leukocyte tyrosine kinase receptor / P08923 / P29376 | | | | | Species: | Danio rerio | | | | | Chr. number: | 17 | | Strand: | -1 | | Band: | | | Gene start: | 31400584 | | Gene end: | 31483469 | | | | | Corresponding Affymetrix probe sets: | | | | | | Cross references: | Ensembl peptide - ENSDARP00000062906
Ensembl peptide - ENSDARP00000061546
NCBI entrez gene - 564470
See in Manteia.
RefSeq - NM_001006660
RefSeq Peptide - NP_001006661
swissprot - F1QVU0
swissprot - F1QBU7
ZFIN ID - ZDB-GENE-030616-115
Ensembl - ENSDARG00000042861
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See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed
Ortholog prediction (from Ensembl)
Paralog prediction (from Ensembl)
| alk / ALK receptor tyrosine kinase / P97793* / Q9UM73* / ALK tyrosine kinase receptor * | ENSDARG00000095833 | 34 | | insra / insulin receptor a / INSR* / P06213* / P15208* / insulin receptor* / Insulin receptor Insulin receptor subunit alpha Insulin receptor subunit beta* | ENSDARG00000011948 | 14 | | igf1ra / insulin-like growth factor 1a receptor / IGF1R* / P08069* / insulin like growth factor 1 receptor* | ENSDARG00000027423 | 14 | | igf1rb / insulin-like growth factor 1b receptor / IGF1R* / P08069* / insulin like growth factor 1 receptor* | ENSDARG00000034434 | 14 | | insrb / insulin receptor b / INSR* / P06213* / P15208* / insulin receptor* / Insulin receptor Insulin receptor subunit alpha Insulin receptor subunit beta* | ENSDARG00000071524 | 14 | | ros1 / c-ros oncogene 1 , receptor tyrosine kinase / P08922* / Q78DX7* / Proto-onco tyrosine-protein kinase ROS * / ROS proto-oncogene 1, receptor tyrosine kinase* | ENSDARG00000087197 | 12 | | ntrk1 / neurotrophic tyrosine kinase, receptor, type 1 / P04629* / Q3UFB7* / neurotrophic receptor tyrosine kinase 1* / High affinity nerve growth factor receptor * | ENSDARG00000004586 | 10 | | ror1 / receptor tyrosine kinase-like orphan receptor 1 / Q01973* / Q9Z139* / Inactive tyrosine-protein kinase transmembrane receptor ROR1 * | ENSDARG00000015176 | 10 | | ntrk2a / neurotrophic tyrosine kinase, receptor, type 2a / NTRK2* / Q16620* / P15209* / BDNF/NT-3 growth factors receptor * / neurotrophic receptor tyrosine kinase 2* | ENSDARG00000059897 | 10 | | ror2 / receptor tyrosine kinase-like orphan receptor 2 / Q01974* / Q9Z138* | ENSDARG00000076227 | 10 | | ntrk3a / neurotrophic tyrosine kinase, receptor, type 3a / NTRK3* / Q16288* / Q6VNS1* / NT-3 growth factor receptor * / neurotrophic receptor tyrosine kinase 3* | ENSDARG00000077228 | 10 | | ntrk3b / neurotrophic tyrosine kinase, receptor, type 3b / NTRK3* / Q16288* / neurotrophic receptor tyrosine kinase 3* | ENSDARG00000086214 | 10 | | ntrk2b / neurotrophic tyrosine kinase, receptor, type 2b / NTRK2* / Q16620* / P15209* / BDNF/NT-3 growth factors receptor * / neurotrophic receptor tyrosine kinase 2* | ENSDARG00000098511 | 10 | | ptk7a / protein tyrosine kinase 7a / PTK7* / Q13308* / Q8BKG3* / Inactive tyrosine-protein kinase 7 * / protein tyrosine kinase 7 (inactive)* | ENSDARG00000011863 | 9 | | ddr2b / discoidin domain receptor tyrosine kinase 2b / DDR2* / Q16832* / Q62371* / Discoidin domain-containing receptor 2 * / discoidin domain receptor tyrosine kinase 2* | ENSDARG00000058695 | 9 | | ddr1 / discoidin domain receptor tyrosine kinase 1 / Q03146* / Q08345* / Epithelial discoidin domain-containing receptor 1 * | ENSDARG00000078523 | 9 | | ddr2a / discoidin domain receptor tyrosine kinase 2a / DDR2* / Q16832* / Q62371* / Discoidin domain-containing receptor 2 * / discoidin domain receptor tyrosine kinase 2* | ENSDARG00000100693 | 9 | | ddr2l / discoidin domain receptor family, member 2, like | ENSDARG00000103830 | 9 | | musk / muscle, skeletal, receptor tyrosine kinase / Q61006* / O15146* / muscle associated receptor tyrosine kinase* / Muscle, skeletal receptor tyrosine-protein kinase * | ENSDARG00000098764 | 2 | | LT631676.1 | ENSDARG00000111743 | 1 |
Protein motifs (from Interpro)
| IPR000719 | Protein kinase domain | | IPR000998 | MAM domain | | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain | | IPR002011 | Tyrosine-protein kinase, receptor class II, conserved site | | IPR002172 | Low-density lipoprotein (LDL) receptor class A repeat | | IPR008266 | Tyrosine-protein kinase, active site | | IPR011009 | Protein kinase-like domain superfamily | | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily | | IPR017441 | Protein kinase, ATP binding site | | IPR020635 | Tyrosine-protein kinase, catalytic domain | | IPR023415 | Low-density lipoprotein (LDL) receptor class A, conserved site |
Gene Ontology (GO)
Pathways (from Reactome)
No match
Phenotype (from MGI, Zfin or HPO)
| ZFA:0000107 | eye | eye iridophore decreased amount , abnormal
eye has fewer parts of type iridophore , abnormal |
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| | ZFA:0000277 | scale | scale melanocyte decreased amount , abnormal
scale iridophore increased amount , abnormal
scale melanocyte increased amount , abnormal |
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| | ZFA:0001058 | caudal fin | caudal fin has fewer parts of type iridophore , abnormal
caudal fin iridophore increased amount , abnormal |
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| | ZFA:0001094 | whole organism | whole organism has fewer parts of type melanocyte , abnormal
whole organism lacks all parts of type xanthophore , abnormal
whole organism lacks all parts of type iridophore , abnormal |
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| | ZFA:0001115 | trunk | trunk melanophore stripe disorganized , abnormal
trunk iridophore decreased amount , abnormal
trunk has fewer parts of type melanophore stripe , abnormal
trunk dermis lacks all parts of type iridophore , abnormal
trunk melanophore stripe malformed , abnormal
trunk melanophore stripe has fewer parts of type melanocyte , abnormal
trunk melanocyte mislocalised , abnormal
trunk dermis has fewer parts of type melanocyte , abnormal
trunk lacks parts or has fewer parts of type melanophore stripe , abnormal
trunk dermis lacks all parts of type xanthophore , abnormal |
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| | ZFA:0001136 | hypodermis | hypodermis iridophore decreased amount , abnormal
hypodermis melanocyte decreased amount , abnormal |
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| | ZFA:0001162 | anal fin | anal fin has fewer parts of type iridophore , abnormal
anal fin iridophore increased amount , abnormal |
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| | ZFA:0001173 | dorsal fin | dorsal fin iridophore increased amount , abnormal |
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| | ZFA:0001463 | melanophore stripe | melanophore stripe spotted , abnormal |
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| | ZFA:0009090 | pigment cell | pigment cell quality , abnormal |
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| | ZFA:0009091 | melanocyte | melanocyte decreased amount , abnormal
melanocyte cell death increased process quality , abnormal |
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| | ZFA:0009198 | xanthophore | xanthophore spatial pattern , abnormal |
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| | ZFA:0009199 | iridophore | iridophore spatial pattern , abnormal
iridophore decreased amount , abnormal
iridophore irregular spatial pattern , abnormal
iridophore absent , abnormal
iridophore increased amount , abnormal
iridophore mislocalised , abnormal
iridophore displaced to trunk , abnormal
iridophore displaced to pupil , abnormal
iridophore displaced to vertebral column dorsal_to, abnormal
iridophore amount , ameliorated
iridophore position , ameliorated
iridophore displaced to swim bladder posterior_to, abnormal
iridophore displaced to dorsal root ganglion , abnormal |
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Interacting proteins (from Reactome)
No match
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