ENSDARG00000095833
Danio rerio kinase alk protein domain tyrosine-protein receptor tyrosine activity site phosphorylation catalytic superfamily atp binding transmembrane development neuron membrane mam serine-threonine class ii conserved active kinase-like wd yvtn repeat-like-containing activation mapk
Features Gene ID: ENSDARG00000095833 Biological name :alk Synonyms : alk / Possible biological names infered from orthology : ALK tyrosine kinase receptor / / Species: Danio rerio Chr. number: 17 Strand: -1 Band: Gene start: 47187870 Gene end: 47305034 Corresponding Affymetrix probe sets: Cross references: Ensembl peptide - ENSDARP00000124055A0A0R4IRF5 F8W3R9 ZDB-GENE-031027-1 ENSDARG00000095833
See co-cited genes in PubMed Ortholog prediction (from Ensembl )Paralog prediction (from Ensembl ) ltk / leukocyte receptor tyrosine kinase / P08923* / P29376* / Leukocyte tyrosine kinase receptor * ENSDARG00000042861 45 insra / insulin receptor a / INSR* / P06213* / P15208* / insulin receptor* / Insulin receptor Insulin receptor subunit alpha Insulin receptor subunit beta* ENSDARG00000011948 16 igf1ra / insulin-like growth factor 1a receptor / IGF1R* / P08069* / insulin like growth factor 1 receptor* ENSDARG00000027423 16 igf1rb / insulin-like growth factor 1b receptor / IGF1R* / P08069* / insulin like growth factor 1 receptor* ENSDARG00000034434 16 insrb / insulin receptor b / INSR* / P06213* / P15208* / insulin receptor* / Insulin receptor Insulin receptor subunit alpha Insulin receptor subunit beta* ENSDARG00000071524 16 ros1 / c-ros oncogene 1 , receptor tyrosine kinase / P08922* / Q78DX7* / Proto-onco tyrosine-protein kinase ROS * / ROS proto-oncogene 1, receptor tyrosine kinase* ENSDARG00000087197 14 ror1 / receptor tyrosine kinase-like orphan receptor 1 / Q01973* / Q9Z139* / Inactive tyrosine-protein kinase transmembrane receptor ROR1 * ENSDARG00000015176 13 ntrk3a / neurotrophic tyrosine kinase, receptor, type 3a / NTRK3* / Q16288* / Q6VNS1* / NT-3 growth factor receptor * / neurotrophic receptor tyrosine kinase 3* ENSDARG00000077228 13 ntrk2b / neurotrophic tyrosine kinase, receptor, type 2b / NTRK2* / Q16620* / P15209* / BDNF/NT-3 growth factors receptor * / neurotrophic receptor tyrosine kinase 2* ENSDARG00000098511 13 ntrk1 / neurotrophic tyrosine kinase, receptor, type 1 / P04629* / Q3UFB7* / neurotrophic receptor tyrosine kinase 1* / High affinity nerve growth factor receptor * ENSDARG00000004586 12 ntrk2a / neurotrophic tyrosine kinase, receptor, type 2a / NTRK2* / Q16620* / P15209* / BDNF/NT-3 growth factors receptor * / neurotrophic receptor tyrosine kinase 2* ENSDARG00000059897 12 ror2 / receptor tyrosine kinase-like orphan receptor 2 / Q01974* / Q9Z138* ENSDARG00000076227 12 ntrk3b / neurotrophic tyrosine kinase, receptor, type 3b / NTRK3* / Q16288* / neurotrophic receptor tyrosine kinase 3* ENSDARG00000086214 12 ddr1 / discoidin domain receptor tyrosine kinase 1 / Q03146* / Q08345* / Epithelial discoidin domain-containing receptor 1 * ENSDARG00000078523 11 ddr2l / discoidin domain receptor family, member 2, like ENSDARG00000103830 11 ptk7a / protein tyrosine kinase 7a / PTK7* / Q13308* / Q8BKG3* / Inactive tyrosine-protein kinase 7 * / protein tyrosine kinase 7 (inactive)* ENSDARG00000011863 10 ddr2b / discoidin domain receptor tyrosine kinase 2b / DDR2* / Q16832* / Q62371* / Discoidin domain-containing receptor 2 * / discoidin domain receptor tyrosine kinase 2* ENSDARG00000058695 10 ddr2a / discoidin domain receptor tyrosine kinase 2a / DDR2* / Q16832* / Q62371* / Discoidin domain-containing receptor 2 * / discoidin domain receptor tyrosine kinase 2* ENSDARG00000100693 10 musk / muscle, skeletal, receptor tyrosine kinase / Q61006* / O15146* / muscle associated receptor tyrosine kinase* / Muscle, skeletal receptor tyrosine-protein kinase * ENSDARG00000098764 2 LT631676.1 ENSDARG00000111743 0
Protein motifs (from Interpro ) IPR000719 Protein kinase domain IPR000998 MAM domain IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain IPR002011 Tyrosine-protein kinase, receptor class II, conserved site IPR008266 Tyrosine-protein kinase, active site IPR011009 Protein kinase-like domain superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily IPR017441 Protein kinase, ATP binding site IPR020635 Tyrosine-protein kinase, catalytic domain IPR026830 ALK tyrosine kinase receptor
Gene Ontology (GO ) nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus biosynthetic process glycosylation anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus biosynthetic process glycosylation anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus biosynthetic process glycosylation anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus biosynthetic process glycosylation anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus biosynthetic process glycosylation anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus biosynthetic process glycosylation anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus biosynthetic process glycosylation anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus biosynthetic process glycosylation anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus biosynthetic process glycosylation anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus biosynthetic process glycosylation anatomical structure development cellular developmental process nitrogen comnitrogen compound metabolic process cell communicell communication cellular metcellular metabolic process primary metaprimary metabolic process regulation oregulation of molecular function organic subsorganic substance metabolic process cellular rescellular response to stimulus biosyntheticbiosynthetic process glycosylatioglycosylation anatomical sanatomical structure development cellular devcellular developmental process catalytic activity, acting on a protein transferase activity signaling receptor activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding catalytic activity, acting on a protein transferase activity signaling receptor activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding catalytic activity, acting on a protein transferase activity signaling receptor activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding catalytic activity, acting on a protein transferase activity signaling receptor activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding catalytic activity, acting on a protein transferase activity signaling receptor activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding catalytic activity, acting on a protein transferase activity signaling receptor activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding catalytic activity, acting on a protein transferase activity signaling receptor activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding catalytic activity, acting on a protein transferase activity signaling receptor activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding catalytic activity, acting on a protein transferase activity signaling receptor activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding catalytic activity, acting on a protein transferase activity signaling receptor activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding catalytic activcatalytic activity, acting on a protein transferase acttransferase activity signaling recepsignaling receptor activity ion bindingion binding carbohydrate decarbohydrate derivative binding organic cyclic organic cyclic compound binding heterocyclic coheterocyclic compound binding small molecule small molecule binding drug bindingdrug binding membrane membrane membrane membrane membrane membrane membrane membrane membrane membrane membranemembrane
Pathways (from Reactome )No match Phenotype (from MGI , Zfin or HPO ) ZFA:0000008 brain brain neuron undifferentiated , abnormal
Show ZFA:0000029 hindbrain hindbrain decreased size , abnormal
Show
Interacting proteins (from Reactome )No match
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