ENSDARG00000054968


Danio rerio

Features
Gene ID: ENSDARG00000054968
  
Biological name :cd40
  
Synonyms : cd40 / CD40 molecule, TNF receptor superfamily member 5
  
Possible biological names infered from orthology : CD40 molecule / O35305 / P25942 / P27512 / Q9Y6Q6 / TNF receptor superfamily member 11a / TNFRSF11A / Tumor necrosis factor receptor superfamily member 11A / Tumor necrosis factor receptor superfamily member 5
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 37823560
Gene end: 37835794
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000114636
NCBI entrez gene - 100270764     See in Manteia.
swissprot - B8X730
ZFIN ID - ZDB-GENE-090313-95
Ensembl - ENSDARG00000054968
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CD40ENSGALG00000007015Gallus gallus
 TNFRSF11AENSGALG00000045642Gallus gallus
 CD40ENSG00000101017Homo sapiens
 Q9Y6Q6ENSG00000141655Homo sapiens
 Cd40ENSMUSG00000017652Mus musculus
 O35305ENSMUSG00000026321Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tnfrsf1b / tumor necrosis factor receptor superfamily, member 1B / P20333* / P25119* / TNF receptor superfamily member 1B*ENSDARG0000007016525
tnfrsf11a / tumor necrosis factor receptor superfamily, member 11a, NFKB activator / CD40* / Q9Y6Q6* / O35305* / P25942* / P27512* / CD40 molecule* / TNF receptor superfamily member 11a* / ...ENSDARG0000008780425
tnfrsf21 / tumor necrosis factor receptor superfamily, member 21 / O75509* / Q9EPU5* / TNF receptor superfamily member 21*ENSDARG0000000180719
zgc:153759 / Q92956* / TNFRSF14* / TNF receptor superfamily member 14* / tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)*ENSDARG0000006896919
si:ch211-261n11.8 / Q92956* / TNFRSF14* / TNF receptor superfamily member 14* / tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)*ENSDARG0000008990118
zgc:153759 / si:dkey-23c22.9 / Q92956* / TNFRSF14* / TNF receptor superfamily member 14* / tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)*ENSDARG0000009238118
si:dkey-23c22.7 / Q92956* / TNFRSF14* / TNF receptor superfamily member 14* / tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)*ENSDARG0000009519318
si:ch211-261n11.7 / Q92956* / TNFRSF14* / TNF receptor superfamily member 14* / tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)*ENSDARG0000006896617
zgc:153631 / Q92956* / TNFRSF14* / TNF receptor superfamily member 14* / tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)*ENSDARG0000006899317
tnfrsf11b / tumor necrosis factor receptor superfamily, member 11b / O95407* / O00300* / O08712* / TNFRSF6B* / TNF receptor superfamily member 6b* / TNF receptor superfamily member 11b* / t...ENSDARG0000009837716
si:dkey-23c22.5 / Q92956* / TNFRSF14* / TNF receptor superfamily member 14* / tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)*ENSDARG0000009289215
CT737125.1 / Q92956* / TNFRSF14* / TNF receptor superfamily member 14* / tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)*ENSDARG0000006899112


Protein motifs (from Interpro)
Interpro ID Name
 IPR001368  TNFR/NGFR cysteine-rich region
 IPR034053  Tumor necrosis factor receptor 5, N-terminal, teleost


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway IEA
 biological_processGO:0035666 TRIF-dependent toll-like receptor signaling pathway IMP
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0097190 apoptotic signaling pathway IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005031 tumor necrosis factor-activated receptor activity IBA
 molecular_functionGO:0042615 CD154 receptor binding IDA


Pathways (from Reactome)
Pathway description
TNFR2 non-canonical NF-kB pathway
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000030173 traf2a / Tnf receptor-associated factor 2a / TRAF2* / P39429* / Q12933* / TNF receptor associated factor 2*  / complex / reaction
 ENSDARG00000022000 traf3 / TNF receptor-associated factor 3 / Q13114* / Q60803*  / complex / reaction
 ENSDARG00000044619 birc2 / baculoviral IAP repeat containing 2 / BIRC3* / Q13489* / Q13490* / Q62210* / baculoviral IAP repeat containing 3* / Baculoviral IAP repeat-containing protein 2 *  / complex / reaction
 ENSDARG00000068141 tnfsf11 / TNF superfamily member 11 / O14788* / O35235* / tumor necrosis factor (ligand) superfamily, member 11*  / complex / reaction
 ENSDARG00000087804 tnfrsf11a / tumor necrosis factor receptor superfamily, member 11a, NFKB activator / CD40* / Q9Y6Q6* / O35305* / P25942* / P27512* / CD40 molecule* / TNF receptor superfamily member 11a* / ...  / complex / reaction
 ENSDARG00000054968 cd40 / CD40 molecule, TNF receptor superfamily member 5 / P27512* / O35305* / P25942* / Q9Y6Q6* / TNFRSF11A* / CD40 molecule* / TNF receptor superfamily member 11a* / Tumor necrosis factor ...  / complex / reaction
 ENSDARG00000074060 map3k14a / mitogen-activated protein kinase kinase kinase 14a / Q9WUL6* / Q99558* / MAP3K14* / mitogen-activated protein kinase kinase kinase 14*  / complex / reaction






 

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