ENSDARG00000068141


Danio rerio

Features
Gene ID: ENSDARG00000068141
  
Biological name :tnfsf11
  
Synonyms : tnfsf11 / TNF superfamily member 11
  
Possible biological names infered from orthology : O14788 / O35235 / tumor necrosis factor (ligand) superfamily, member 11
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 18023288
Gene end: 18043298
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000089126
NCBI entrez gene - 100331628     See in Manteia.
swissprot - E7F3U1
ZFIN ID - ZDB-GENE-090805-2
Ensembl - ENSDARG00000068141
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TNFSF11ENSGALG00000026163Gallus gallus
 O14788ENSG00000120659Homo sapiens
 O35235ENSMUSG00000022015Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tnfsf10 / TNF superfamily member 10 / P50591* / P50592* / tumor necrosis factor (ligand) superfamily, member 10*ENSDARG0000005724122
tnfsf10l / TNF superfamily member 10, likeENSDARG0000000419621
tnfsf10l3 / tumor necrosis factor (ligand) superfamily, member 10 like 3ENSDARG0000003274619
tnfsf10l4 / tumor necrosis factor (ligand) superfamily, member 10 like 4ENSDARG0000005806818


Protein motifs (from Interpro)
Interpro ID Name
 IPR006052  Tumour necrosis factor domain
 IPR008983  Tumour necrosis factor-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response IEA
 biological_processGO:0009612 response to mechanical stimulus IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005164 tumor necrosis factor receptor binding IEA


Pathways (from Reactome)
Pathway description
TNFR2 non-canonical NF-kB pathway
TNFs bind their physiological receptors
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000030173 traf2a / Tnf receptor-associated factor 2a / TRAF2* / P39429* / Q12933* / TNF receptor associated factor 2*  / complex / reaction
 ENSDARG00000022000 traf3 / TNF receptor-associated factor 3 / Q13114* / Q60803*  / complex / reaction
 ENSDARG00000044619 birc2 / baculoviral IAP repeat containing 2 / BIRC3* / Q13489* / Q13490* / Q62210* / baculoviral IAP repeat containing 3* / Baculoviral IAP repeat-containing protein 2 *  / complex / reaction
 ENSDARG00000068141 tnfsf11 / TNF superfamily member 11 / O14788* / O35235* / tumor necrosis factor (ligand) superfamily, member 11*  / complex
 ENSDARG00000087804 tnfrsf11a / tumor necrosis factor receptor superfamily, member 11a, NFKB activator / CD40* / Q9Y6Q6* / O35305* / P25942* / P27512* / CD40 molecule* / TNF receptor superfamily member 11a* / ...  / complex / reaction
 ENSDARG00000054968 cd40 / CD40 molecule, TNF receptor superfamily member 5 / P27512* / O35305* / P25942* / Q9Y6Q6* / TNFRSF11A* / CD40 molecule* / TNF receptor superfamily member 11a* / Tumor necrosis factor ...  / complex / reaction
 ENSDARG00000074060 map3k14a / mitogen-activated protein kinase kinase kinase 14a / Q9WUL6* / Q99558* / MAP3K14* / mitogen-activated protein kinase kinase kinase 14*  / complex / reaction






 

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