ENSDARG00000056122


Danio rerio

Features
Gene ID: ENSDARG00000056122
  
Biological name :gdi1
  
Synonyms : gdi1 / GDP dissociation inhibitor 1
  
Possible biological names infered from orthology : P31150 / P50396 / Rab GDP dissociation inhibitor alpha
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 26063149
Gene end: 26077038
  
Corresponding Affymetrix probe sets: Dr.18113.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000111451
NCBI entrez gene - 554985     See in Manteia.
swissprot - A2AR68
ZFIN ID - ZDB-GENE-050522-504
Ensembl - ENSDARG00000056122
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GDI1ENSG00000203879Homo sapiens
 Gdi1ENSMUSG00000015291Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gdi2 / GDP dissociation inhibitor 2 / P50395* / Q61598* / Rab GDP dissociation inhibitor beta *ENSDARG0000000545185
zgc:112334ENSDARG0000010292467
chm / choroideremia (Rab escort protein 1) / CHML* / P26374* / P24386* / choroideremia-like* / CHM, Rab escort protein 1* / CHM like, Rab escort protein 2* / choroidermia (RAB escort protein 1)*ENSDARG0000000384523


Protein motifs (from Interpro)
Interpro ID Name
 IPR000806  Rab GDI protein
 IPR018203  GDP dissociation inhibitor
 IPR023753  FAD/NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0050790 regulation of catalytic activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005092 GDP-dissociation inhibitor activity IEA
 molecular_functionGO:0005093 Rab GDP-dissociation inhibitor activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000006545 rgp1 / GP1 homolog, RAB6A GEF complex partner 1 / Q92546* / Q8BHT7* / RAB6A-GEF complex partner protein 2 * / RGP1 homolog, RAB6A GEF complex partner 1*  / reaction
 ENSDARG00000034771 rab13 / Q7T3A4 / RAB13, member RAS oncogene family / Q9DD03* / P51153* / Ras-related protein Rab-13 *  / complex
 ENSDARG00000020497 rab7 / RAB7, member RAS oncogene family / RAB7A* / P51150* / P51149* / RAB7A, member RAS oncogene family*  / complex
 ENSDARG00000006399 ywhae1 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 / YWHAE* / P62259* / P62258* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase act...  / reaction
 ENSDARG00000029663 rab1ab / RAB1A, member RAS oncogene family b / Rab1* / RAB1A* / P62821* / P62820* / Ras-related protein Rab-1A * / RAB1A, member RAS oncogene family*  / complex
 ENSDARG00000046106 rab10 / RAB10, member RAS oncogene family / P61026*  / complex
 ENSDARG00000056347 rab3aa / RAB3A, member RAS oncogene family, a / RAB3A* / P63011* / P20336* / RAB3A, member RAS oncogene family*  / complex
 ENSDARG00000055291 rab18a / RAB18A, member RAS oncogene family / RAB18* / Q9NP72* / P35293* / RAB18, member RAS oncogene family*  / complex
 ENSDARG00000056559 ccz1 / CCZ1 homolog, vacuolar protein trafficking and biogenesis associated / CCZ1B* / P86790* / P86791* / Q8C1Y8* / Vacuolar fusion * / CCZ1 homolog B, vacuolar protein trafficking and bi...  / reaction
 ENSDARG00000045027 rab9a / RAB9A, member RAS oncogene family / Rab9* / Q9R0M6* / P51151* / RAB9, member RAS oncogene family*  / complex
 ENSDARG00000014592 dennd1a / DENN/MADD domain containing 1A / Q8K382* / Q8TEH3* / DENN domain containing 1A* / DENN domain-containing protein 1A *  / reaction
 ENSDARG00000062968 sbf1 / SET binding factor 1 / O95248* / Q6ZPE2*  / reaction
 ENSDARG00000062721 dennd4a / DENN/MADD domain containing 4A / Q7Z401* / DENN domain containing 4A*  / reaction
 ENSDARG00000059460 sbf2 / SET binding factor 2 / Q86WG5*  / reaction
 ENSDARG00000043835 rab3ab / RAB3A, member RAS oncogene family, b / RAB3A* / P63011* / P20336* / RAB3A, member RAS oncogene family*  / complex
 ENSDARG00000078585 mon1a / MON1 secretory trafficking family member A / Q86VX9* / MON1 homolog A, secretory trafficking associated*  / reaction
 ENSDARG00000090183 gapvd1 / GTPase activating protein and VPS9 domains 1 / Q14C86* / Q6PAR5* / GTPase-activating protein and VPS9 domain-containing protein 1 *  / reaction
 ENSDARG00000044136 rab3gap2 / RAB3 GTPase activating protein subunit 2 (non-catalytic) / Q9H2M9* / RAB3 GTPase activating non-catalytic protein subunit 2*  / reaction
 ENSDARG00000074246 rab14 / RAB14, member RAS oncogene family / P61106* / Q91V41*  / complex
 ENSDARG00000089428 rab12 / RAB12, member RAS oncogene family / Q6IQ22*  / complex
 ENSDARG00000067920 rab8a / RAB8A, member RAS oncogene family / P55258* / P61006*  / complex
 ENSDARG00000103935 rab27a / RAB27A, member RAS oncogene family / P51159*  / complex
 ENSDARG00000078503 si:dkey-76b14.2 / Q8CFK6* / Q8IV53* / DENND1C* / DENN domain containing 1C* / DENN domain-containing protein 1C *  / reaction
 ENSDARG00000098344 Q6DHC1 / rab18b / RAB18B, member RAS oncogene family / RAB18* / Q9NP72* / P35293* / RAB18, member RAS oncogene family*  / complex
 ENSDARG00000102078 CABZ01072548.1 / RAB35* / Q15286* / RAB35, member RAS oncogene family*  / complex
 ENSDARG00000102914 dennd4b / DENN/MADD domain containing 4B / O75064* / Q3U1Y4* / DENN domain containing 4B* / Mus musculus DENN/MADD domain containing 4B (Dennd4b), transcript variant 2, mRNA.*  / reaction
 ENSDARG00000077618 rin3 / Ras and Rab interactor 3 / P59729* / Q8TB24*  / reaction
 ENSDARG00000103714 rab6a / RAB6A, member RAS oncogene family / RAB6C* / RAB6D* / P20340* / Q9H0N0* / P35279* / RAB6C, member RAS oncogene family* / RAB6D, member RAS oncogene family*  / complex
 ENSDARG00000102766 dennd4c / DENN/MADD domain containing 4C / Q5VZ89* / DENN domain containing 4C*  / reaction
 ENSDARG00000100752 RAB21 / zgc:154045 / P35282* / Q9UL25* / RAB21, member RAS oncogene family*  / complex






 

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