ENSDARG00000056753


Danio rerio

Features
Gene ID: ENSDARG00000056753
  
Biological name :dctn1b
  
Synonyms : dctn1b / dynactin 1b
  
Possible biological names infered from orthology : DCTN1 / dynactin subunit 1 / Mus musculus dynactin 1 (Dctn1), transcript variant 4, mRNA. / O08788 / Q14203
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 11581942
Gene end: 11667661
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000093188
Ensembl peptide - ENSDARP00000139684
swissprot - A0A0R4IW36
swissprot - F6PC33
ZFIN ID - ZDB-GENE-050419-28
Ensembl - ENSDARG00000056753
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DCTN1ENSG00000204843Homo sapiens
 Dctn1ENSMUSG00000031865Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dctn1a / dynactin 1a / DCTN1* / Q14203* / dynactin subunit 1*ENSDARG0000001974374
clip1a / CAP-GLY domain containing linker protein 1aENSDARG0000007872218
cep350 / centrosomal protein 350ENSDARG0000005800012
clip2 / CAP-GLY domain containing linker protein 2 / Q9UDT6* / Q9Z0H8*ENSDARG0000005959612
clip3 / CAP-GLY domain containing linker protein 3 / B9EHT4* / Q96DZ5* / AC006030.1*ENSDARG000000544564
CABZ01072096.1ENSDARG000000794834
CLIP4 / si:dkeyp-47f9.4 / Q8CI96* / Q8N3C7* / CAP-Gly domain-containing linker protein 4 * / CAP-Gly domain containing linker protein family member 4*ENSDARG000000969614
tbcb / tubulin folding cofactor B / CLIP1* / P30622* / Q922J3* / CAP-Gly domain containing linker protein 1*ENSDARG000000684041
zgc:103755 / E9Q309* / CEP350* / Q5VT06* / centrosomal protein 350* / Centrosome-associated protein 350 *ENSDARG000001046630


Protein motifs (from Interpro)
Interpro ID Name
 IPR000938  CAP Gly-rich domain
 IPR022157  Dynein associated protein
 IPR027663  Dynactin subunit 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010970 transport along microtubule IEA
 biological_processGO:0060219 camera-type eye photoreceptor cell differentiation IGI
 cellular_componentGO:0005869 dynactin complex IEA
 molecular_functionGO:0070840 dynein complex binding IEA


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000035924 dync1li2 / dynein, cytoplasmic 1, light intermediate chain 2 / O43237* / Q6PDL0* / Cytoplasmic dynein 1 light intermediate chain 2 *  / complex
 ENSDARG00000058454 dynll1 / dynein, light chain, LC8-type 1 / P63168* / P63167* / BC048507* / cDNA sequence BC048507* / Dynein light chain 1, cytoplasmic *  / complex
 ENSDARG00000060948 dync1i1 / dynein, cytoplasmic 1, intermediate chain 1 / O14576* / O88485* / Cytoplasmic dynein 1 intermediate chain 1 *  / complex
 ENSDARG00000056090 capza1b / capping protein (actin filament) muscle Z-line, alpha 1b / P52907* / CAPZA1* / 4933400A11Rik* / RIKEN cDNA 4933400A11 gene* / capping actin protein of muscle Z-line alpha subunit 1*  / complex
 ENSDARG00000041363 dctn3 / dynactin 3 (p22) / O75935* / Q9Z0Y1* / dynactin subunit 3*  / complex
 ENSDARG00000056753 dctn1b / dynactin 1b / DCTN1* / O08788* / Q14203* / dynactin subunit 1* / Mus musculus dynactin 1 (Dctn1), transcript variant 4, mRNA.*  / complex
 ENSDARG00000100252 capzb / capping protein (actin filament) muscle Z-line, beta / P47756* / capping actin protein of muscle Z-line beta subunit*  / complex
 ENSDARG00000069790 dynll2a / dynein, light chain, LC8-type 2a / Q9D0M5* / DYNLL2* / Q96FJ2* / dynein light chain LC8-type 2* / Dynein light chain 2, cytoplasmic *  / complex
 ENSDARG00000019743 dctn1a / dynactin 1a / DCTN1* / Q14203* / dynactin subunit 1*  / complex
 ENSDARG00000098317 dync1li1 / dynein, cytoplasmic 1, light intermediate chain 1 / Q8R1Q8* / Q9Y6G9* / Cytoplasmic dynein 1 light intermediate chain 1 *  / complex






 

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