ENSDARG00000076928


Danio rerio

Features
Gene ID: ENSDARG00000076928
  
Biological name :tet2
  
Synonyms : tet2 / tet methylcytosine dioxygenase 2
  
Possible biological names infered from orthology : Mus musculus tet methylcytosine dioxygenase 2 (Tet2), transcript variant 2, mRNA. / Q4JK59 / Q6N021
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 26356205
Gene end: 26402046
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000101295
Ensembl peptide - ENSDARP00000144252
Ensembl peptide - ENSDARP00000156471
NCBI entrez gene - 101887161     See in Manteia.
swissprot - A0A286YAQ6
swissprot - E7F958
ZFIN ID - ZDB-GENE-090312-98
Ensembl - ENSDARG00000076928
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TET2ENSGALG00000010592Gallus gallus
 TET2ENSG00000168769Homo sapiens
 Tet2ENSMUSG00000040943Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tet3 / tet methylcytosine dioxygenase 3 / O43151* / Q8BG87* / Mus musculus tet methylcytosine dioxygenase 3 (Tet3), transcript variant 1, mRNA.*ENSDARG0000006264624
tet1 / tet methylcytosine dioxygenase 1 / Q3URK3* / Q8NFU7*ENSDARG0000007523024
cxxc4 / CXXC finger 4 / Q6NXI8* / CXXC finger protein 4* / CXXC-type zinc finger protein 4 *ENSDARG000000778173
cxxc5b / CXXC finger protein 5b / CXXC5* / Q7LFL8* / Q91WA4* / CXXC finger protein 5* / Mus musculus CXXC finger 5 (Cxxc5), transcript variant 2, mRNA.*ENSDARG000000757352
cxxc5a / CXXC finger protein 5a / CXXC5* / Q7LFL8* / Q91WA4* / CXXC finger protein 5* / Mus musculus CXXC finger 5 (Cxxc5), transcript variant 2, mRNA.*ENSDARG000000788652


Protein motifs (from Interpro)
Interpro ID Name
 IPR024779  2OGFeDO, oxygenase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030097 hemopoiesis IGI
 biological_processGO:0030218 erythrocyte differentiation IGI
 biological_processGO:0060319 primitive erythrocyte differentiation IMP
 biological_processGO:0070989 oxidative demethylation IMP
 biological_processGO:0098508 endothelial to hematopoietic transition IGI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood nucleate erythrocyte morphology , abnormal
blood nucleate erythrocyte circular , abnormal
blood nucleate erythrocyte decreased amount , abnormal
Show

 ZFA:0000008 brain brain morphology , abnormal
Show

 ZFA:0000014 dorsal aorta dorsal aorta ventral region decreased amount , abnormal
dorsal aorta nucleus broken , abnormal
dorsal aorta decreased amount , abnormal
dorsal aorta hematopoietic stem cell decreased amount , abnormal
Show

 ZFA:0000033 intermediate cell mass of mesoderm intermediate cell mass of mesoderm erythroid progenitor cell decreased amount , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000529 kidney kidney myeloid cell dysplastic , abnormal
kidney hematopoietic multipotent progenitor cell dysplastic , abnormal
kidney erythroid lineage cell morphology , abnormal
Show

 ZFA:0000669 head kidney head kidney common myeloid progenitor increased amount , abnormal
head kidney nucleate erythrocyte decreased amount , abnormal
head kidney myeloid cell dysplastic , abnormal
head kidney hematopoietic multipotent progenitor cell dysplastic , abnormal
head kidney erythroid lineage cell morphology , abnormal
head kidney hematopoietic multipotent progenitor cell increased amount , abnormal
Show

 ZFA:0001078 thymus thymus T cell absent , abnormal
Show

 ZFA:0001115 trunk trunk decreased amount , abnormal
trunk curved , abnormal
Show

 ZFA:0005241 polychromatophilic erythroblast polychromatophilic erythroblast increased amount , abnormal
Show

 ZFA:0009015 erythroid progenitor cell erythroid progenitor cell increased accumulation intermediate cell mass of mesoderm , abnormal
Show

 ZFA:0009141 macrophage macrophage absent , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte ribosome increased amount , abnormal
Show

 ZFA:0009327 neutrophil neutrophil absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr