ENSDARG00000078649


Danio rerio
receptorsignalingmembraneil21r.2shorthematopoietinfamilyconservedsitefibronectintypeiiiimmunoglobulin-likefoldcytokine-mediatedpathwayintegralcomponentcytokineactivityinterleukin-

Features
Gene ID: ENSDARG00000078649
  
Biological name :il21r.2
  
Synonyms : il21r.2 / interleukin 21 receptor, tandem duplicate 2
  
Possible biological names infered from orthology : IL21R / interleukin 21 receptor / Q9HBE5 / Q9JHX3
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 45315477
Gene end: 45326897
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000080852
NCBI entrez gene - 100134975     See in Manteia.
RefSeq - NM_001113509
RefSeq Peptide - NP_001106981
swissprot - A8WHA8
ZFIN ID - ZDB-GENE-080108-7
Ensembl - ENSDARG00000078649
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IL21RENSGALG00000006318Gallus gallus
 IL21RENSG00000103522Homo sapiens
 Il21rENSMUSG00000030745Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
il21r.1 / interleukin 21 receptor, tandem duplicate 1 / IL21R* / Q9JHX3* / Q9HBE5* / interleukin 21 receptor*ENSDARG0000006996121


Protein motifs (from Interpro)
Interpro ID Name
 IPR003531  Short hematopoietin receptor, family 1, conserved site
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
cell communicationresponse to chemicalcellular response to stimuluscell communicationresponse to chemicalcellular response to stimuluscell communicationresponse to chemicalcellular response to stimuluscell communicationresponse to chemicalcellular response to stimuluscell communicationresponse to chemicalcellular response to stimuluscell communicationresponse to chemicalcellular response to stimuluscell communicationresponse to chemicalcellular response to stimuluscell communicationresponse to chemicalcellular response to stimuluscell communicationresponse to chemicalcellular response to stimuluscell communicationresponse to chemicalcellular response to stimuluscell communicationcell communicationresponse to chemicalresponse to chemicalcellular response to stimuluscellular response to stimulus
signaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activity
membranemembranemembranemembranemembranemembranemembranemembranemembranemembranemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004896 cytokine receptor activity IEA


Pathways (from Reactome)
Pathway description
Interleukin-21 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000076182 stat1b / signal transducer and activator of transcription 1b / STAT1* / P42224* / signal transducer and activator of transcription 1*  / complex
 ENSDARG00000010252 jak3 / Janus kinase 3 (a protein tyrosine kinase, leukocyte) / P52333* / Janus kinase 3*  / complex
 ENSDARG00000020625 jak1 / Janus kinase 1 / P23458*  / complex
 ENSDARG00000068858 il2rga / interleukin 2 receptor, gamma a / IL2RG* / P34902* / P31785* / Gm20489* / AL590764.2* / interleukin 2 receptor subunit gamma* / Cytokine receptor common subunit gamma *  / complex
 ENSDARG00000053702 il2rgb / interleukin 2 receptor, gamma b / IL2RG* / P34902* / P31785* / Gm20489* / AL590764.2* / interleukin 2 receptor subunit gamma* / Cytokine receptor common subunit gamma *  / complex
 ENSDARG00000028731 stat4 / signal transducer and activator of transcription 4 / Q14765*  / complex






 

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