ENSDARG00000096418


Danio rerio

Features
Gene ID: ENSDARG00000096418
  
Biological name :ighv14-1
  
Synonyms : ighv14-1 / immunoglobulin heavy variable 14-1
  
Possible biological names infered from orthology : A0A075B6Q5 / A0A0A0MS15 / A0A0B4J1V0 / A0A0B4J1V1 / A0A0B4J1V6 / A0A0B4J1X5 / A0A0B4J1X8 / A0A0B4J1Y9 / A0A0C4DH32 / A0A0C4DH42 / A0A0J9YX35 / AC136428.1 / Ighv16-1 / IGHV3-11 / IGHV3-13 / IGHV3-15 / IGHV3-20 / IGHV3-21 / IGHV3-23 / IGHV3-30 / IGHV3-33 / IGHV3-35 / IGHV3-38 / IGHV3-43 / IGHV3-48 / IGHV3-49 / IGHV3-53 / IGHV3-64 / IGHV3-64D / IGHV3-66 / IGHV3-7 / IGHV3-72 / IGHV3-73 / IGHV3-74 / IGHV3OR15-7 / IGHV3OR16-10 / IGHV3OR16-13 / IGHV3OR16-8 / IGHV3OR16-9 / Ighv4-1 / Ighv5-12 / Ighv5-16 / Ighv5-17 / Ighv5-6 / Ighv5-9 / Ighv5-9-1 / Ighv6-3 / Ighv6-5 / Ighv6-6 / Ighv7-1 / Ighv7-3 / immunoglobulin heavy variable 3-11 (gene/pseudogene) / immunoglobulin heavy variable 3-13 / immunoglobulin heavy variable 3-15 / immunoglobulin heavy variable 3-20 / immunoglobulin heavy variable 3-21 / immunoglobulin heavy variable 3-23 / immunoglobulin heavy variable 3-30 / immunoglobulin heavy variable 3-33 / immunoglobulin heavy variable 3-35 (non-functional) / immunoglobulin heavy variable 3-38 (non-functional) / immunoglobulin heavy variable 3-43 / immunoglobulin heavy variable 3-48 / immunoglobulin heavy variable 3-49 / immunoglobulin heavy variable 3-53 / immunoglobulin heavy variable 3-64 / immunoglobulin heavy variable 3-64D / immunoglobulin heavy variable 3-66 / immunoglobulin heavy variable 3-7 / immunoglobulin heavy variable 3-72 / immunoglobulin heavy variable 3-73 / immunoglobulin heavy variable 3-74 / immunoglobulin heavy variable 3/OR15-7 (pseudogene) / immunoglobulin heavy variable 3/OR16-10 (non-functional) / immunoglobulin heavy variable 3/OR16-13 (non-functional) / immunoglobulin heavy variable 3/OR16-8 (non-functional) / immunoglobulin heavy variable 3/OR16-9 (non-functional) / P01762 / P01763 / P01764 / P01766 / P01767 / P01768 / P01772 / P01780 / P0DP03
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 34026706
Gene end: 34027178
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000126248
swissprot - M9MMG5
ZFIN ID - ZDB-GENE-040514-42
Ensembl - ENSDARG00000096418
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AC136428.1ENSG00000259680Homo sapiens
 IGHV3-15ENSG00000211943Homo sapiens
 IGHV3-20ENSG00000211946Homo sapiens
 IGHV3-21ENSG00000211947Homo sapiens
 IGHV3-35ENSG00000211957Homo sapiens
 IGHV3-38ENSG00000211958Homo sapiens
 IGHV3-43ENSG00000232216Homo sapiens
 IGHV3-49ENSG00000211965Homo sapiens
 IGHV3-64ENSG00000223648Homo sapiens
 IGHV3-64DENSG00000282639Homo sapiens
 IGHV3-66ENSG00000211972Homo sapiens
 IGHV3-72ENSG00000225698Homo sapiens
 IGHV3-73ENSG00000211976Homo sapiens
 IGHV3-74ENSG00000224650Homo sapiens
 IGHV3OR15-7ENSG00000259490Homo sapiens
 IGHV3OR16-10ENSG00000233732Homo sapiens
 IGHV3OR16-13ENSG00000271178Homo sapiens
 IGHV3OR16-8ENSG00000271130Homo sapiens
 IGHV3OR16-9ENSG00000270472Homo sapiens
 P01762ENSG00000211941Homo sapiens
 P01763ENSG00000211964Homo sapiens
 P01764ENSG00000211949Homo sapiens
 P01766ENSG00000211942Homo sapiens
 P01767ENSG00000211967Homo sapiens
 P01768ENSG00000270550Homo sapiens
 P01772ENSG00000211955Homo sapiens
 P01780ENSG00000211938Homo sapiens
 Ighv16-1ENSMUSG00000076661Mus musculus
 Ighv4-1ENSMUSG00000076655Mus musculus
 Ighv5-12ENSMUSG00000095429Mus musculus
 Ighv5-16ENSMUSG00000094194Mus musculus
 Ighv5-17ENSMUSG00000095571Mus musculus
 Ighv5-6ENSMUSG00000094951Mus musculus
 Ighv5-9ENSMUSG00000095285Mus musculus
 Ighv5-9-1ENSMUSG00000095210Mus musculus
 Ighv6-3ENSMUSG00000076677Mus musculus
 Ighv6-5ENSMUSG00000096407Mus musculus
 Ighv6-6ENSMUSG00000076680Mus musculus
 Ighv7-1ENSMUSG00000076665Mus musculus
 Ighv7-3ENSMUSG00000076652Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006910 phagocytosis, recognition IBA
 biological_processGO:0006911 phagocytosis, engulfment IBA
 biological_processGO:0006958 complement activation, classical pathway IBA
 biological_processGO:0042742 defense response to bacterium IBA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0050853 B cell receptor signaling pathway IBA
 biological_processGO:0050871 positive regulation of B cell activation IBA
 cellular_componentGO:0009897 external side of plasma membrane IBA
 cellular_componentGO:0042571 immunoglobulin complex, circulating IBA
 cellular_componentGO:0072562 blood microparticle IBA
 molecular_functionGO:0003823 antigen binding IBA
 molecular_functionGO:0034987 immunoglobulin receptor binding IBA


Pathways (from Reactome)
Pathway description
Initial triggering of complement
Classical antibody-mediated complement activation
FCGR activation
Regulation of actin dynamics for phagocytic cup formation
Role of phospholipids in phagocytosis
Regulation of Complement cascade
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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