Manteia

ENSG00000224650

Homo sapiens

Features

Gene ID:	ENSG00000224650

Biological name :	IGHV3-74

Synonyms :	A0A0B4J1X5 / IGHV3-74 / immunoglobulin heavy variable 3-74

Possible biological names infered from orthology :

Species:	Homo sapiens

Chr. number:	14
Strand:	-1
Band:	q32.33
Gene start:	106810442
Gene end:	106811131

Corresponding Affymetrix probe sets:	239705_at (Human Genome U133 Plus 2.0 Array)

Cross references:	Ensembl peptide - ENSP00000394447 swissprot - A0A0B4J1X5 Ensembl - ENSG00000224650

See gene description in GeneCards
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
ighv14-1	ENSDARG00000096418	Danio rerio

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
IGHV3OR16-13 / immunoglobulin heavy variable 3/OR16-13 (non-functional)	ENSG00000271178	97
P01764 / IGHV3-23 / immunoglobulin heavy variable 3-23	ENSG00000211949	90
P01780 / IGHV3-7 / immunoglobulin heavy variable 3-7	ENSG00000211938	89
P01763 / IGHV3-48 / immunoglobulin heavy variable 3-48	ENSG00000211964	89
IGHV3-64 / A0A075B6Q5 / immunoglobulin heavy variable 3-64	ENSG00000223648	89
IGHV3-66 / A0A0C4DH42 / immunoglobulin heavy variable 3-66	ENSG00000211972	88
P01762 / IGHV3-11 / immunoglobulin heavy variable 3-11 (gene/pseudogene)	ENSG00000211941	87
IGHV3-21 / A0A0B4J1V1 / immunoglobulin heavy variable 3-21	ENSG00000211947	87
P01772 / IGHV3-33 / immunoglobulin heavy variable 3-33	ENSG00000211955	87
IGHV3OR16-10 / immunoglobulin heavy variable 3/OR16-10 (non-functional)	ENSG00000233732	87
IGHV3-20 / A0A0C4DH32 / immunoglobulin heavy variable 3-20	ENSG00000211946	86
P01767 / IGHV3-53 / immunoglobulin heavy variable 3-53	ENSG00000211967	86
IGHV3-43 / A0A0B4J1X8 / immunoglobulin heavy variable 3-43	ENSG00000232216	86
P01768 / P0DP03 / IGHV3-30 / immunoglobulin heavy variable 3-30	ENSG00000270550	86
IGHV3-64D / A0A0J9YX35 / immunoglobulin heavy variable 3-64D	ENSG00000282639	86
P01766 / IGHV3-13 / immunoglobulin heavy variable 3-13	ENSG00000211942	85
IGHV3-35 / immunoglobulin heavy variable 3-35 (non-functional)	ENSG00000211957	84
IGHV3-38 / immunoglobulin heavy variable 3-38 (non-functional)	ENSG00000211958	83
IGHV3-15 / A0A0B4J1V0 / immunoglobulin heavy variable 3-15	ENSG00000211943	82
IGHV3-73 / A0A0B4J1V6 / immunoglobulin heavy variable 3-73	ENSG00000211976	82

Protein motifs (from Interpro)

Interpro ID

Name

No match

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0002250	adaptive immune response	IEA
biological_process	GO:0002376	immune system process	IEA
biological_process	GO:0006910	phagocytosis, recognition	IBA
biological_process	GO:0006911	phagocytosis, engulfment	IBA
biological_process	GO:0006958	complement activation, classical pathway	IBA
biological_process	GO:0042742	defense response to bacterium	IBA
biological_process	GO:0045087	innate immune response	IBA
biological_process	GO:0050853	B cell receptor signaling pathway	IBA
biological_process	GO:0050871	positive regulation of B cell activation	IBA
cellular_component	GO:0005576	extracellular region	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0009897	external side of plasma membrane	IBA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0042571	immunoglobulin complex, circulating	IBA
cellular_component	GO:0072562	blood microparticle	IBA
molecular_function	GO:0003823	antigen binding	IBA
molecular_function	GO:0034987	immunoglobulin receptor binding	IBA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr