ENSG00000211947


Homo sapiens
immuneresponsemembraneIGHV3-21phagocytosisactivationpathwaybcellreceptorplasmaimmunoglobulinbindingadaptiveprocessrecognitionengulfmentcomplementclassicaldefensebacteriuminnatesignalingregulationextracellularregionexternalsidecomplexcirculatingblood

Features
Gene ID: ENSG00000211947
  
Biological name :IGHV3-21
  
Synonyms : A0A0B4J1V1 / IGHV3-21 / immunoglobulin heavy variable 3-21
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q32.33
Gene start: 106235064
Gene end: 106235594
  
Corresponding Affymetrix probe sets: 216557_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000375016
swissprot - A0A0B4J1V1
Ensembl - ENSG00000211947
  
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ighv14-1ENSDARG00000096418Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P01763 / IGHV3-48 / immunoglobulin heavy variable 3-48ENSG0000021196495
P01762 / IGHV3-11 / immunoglobulin heavy variable 3-11 (gene/pseudogene)ENSG0000021194190
P01780 / IGHV3-7 / immunoglobulin heavy variable 3-7ENSG0000021193889
IGHV3-74 / A0A0B4J1X5 / immunoglobulin heavy variable 3-74ENSG0000022465087
P01764 / IGHV3-23 / immunoglobulin heavy variable 3-23ENSG0000021194986
P01766 / IGHV3-13 / immunoglobulin heavy variable 3-13ENSG0000021194285
IGHV3-66 / A0A0C4DH42 / immunoglobulin heavy variable 3-66ENSG0000021197285
IGHV3OR16-10 / immunoglobulin heavy variable 3/OR16-10 (non-functional)ENSG0000023373285
IGHV3-64 / A0A075B6Q5 / immunoglobulin heavy variable 3-64ENSG0000022364884
IGHV3OR16-13 / immunoglobulin heavy variable 3/OR16-13 (non-functional)ENSG0000027117884
P01772 / IGHV3-33 / immunoglobulin heavy variable 3-33ENSG0000021195583
P01768 / P0DP03 / IGHV3-30 / immunoglobulin heavy variable 3-30ENSG0000027055083
IGHV3-20 / A0A0C4DH32 / immunoglobulin heavy variable 3-20ENSG0000021194682
P01767 / IGHV3-53 / immunoglobulin heavy variable 3-53ENSG0000021196782
IGHV3-43 / A0A0B4J1X8 / immunoglobulin heavy variable 3-43ENSG0000023221682
IGHV3OR16-8 / immunoglobulin heavy variable 3/OR16-8 (non-functional)ENSG0000027113082
IGHV3-64D / A0A0J9YX35 / immunoglobulin heavy variable 3-64DENSG0000028263981
IGHV3-35 / immunoglobulin heavy variable 3-35 (non-functional)ENSG0000021195780
AC136428.1ENSG0000025968080
IGHV3-38 / immunoglobulin heavy variable 3-38 (non-functional)ENSG0000021195879


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
immune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune responsecell recognitionestablishment of localizationcellular component organizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processimmune effector processresponse to stressresponse to external stimulusresponse to biotic stimuluscell communicationcellular response to stimuluscell activationimmune resimmune responsecell recogcell recognitionestablishmestablishment of localizationcellular ccellular component organizationnitrogen cnitrogen compound metabolic processprimary meprimary metabolic processorganic suorganic substance metabolic processimmune effimmune effector processresponse tresponse to stressresponse tresponse to external stimulusresponse tresponse to biotic stimuluscell commucell communicationcellular rcellular response to stimuluscell activcell activation
antigen bindingprotein bindingantigen bindingprotein bindingantigen bindingprotein bindingantigen bindingprotein bindingantigen bindingprotein bindingantigen bindingprotein bindingantigen bindingprotein bindingantigen bindingprotein bindingantigen bindingprotein bindingantigen bindingprotein bindingantigen bindingantigen bindingprotein bindingprotein binding
extracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regionextracellular regioncellcellmembranemembraneprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006910 phagocytosis, recognition IBA
 biological_processGO:0006911 phagocytosis, engulfment IBA
 biological_processGO:0006958 complement activation, classical pathway IBA
 biological_processGO:0042742 defense response to bacterium IBA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0050853 B cell receptor signaling pathway IBA
 biological_processGO:0050871 positive regulation of B cell activation IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0042571 immunoglobulin complex, circulating IBA
 cellular_componentGO:0072562 blood microparticle IBA
 molecular_functionGO:0003823 antigen binding IBA
 molecular_functionGO:0034987 immunoglobulin receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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