ENSDARG00000098231


Danio rerio

Features
Gene ID: ENSDARG00000098231
  
Biological name :HHEX
  
Synonyms : hematopoietically expressed homeobox / HHEX
  
Possible biological names infered from orthology : Hematopoietically-expressed homeobox protein Hhex / P43120 / Q03014
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 47663419
Gene end: 47667745
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000137249
swissprot - A0A0G2KXR6
Ensembl - ENSDARG00000098231
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HHEXENSGALG00000030008Gallus gallus
 HHEXENSG00000152804Homo sapiens
 HhexENSMUSG00000024986Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dbx1b / developing brain homeobox 1b / DBX1* / P52950* / A6NMT0* / Homeobox protein DBX1 * / developing brain homeobox 1*ENSDARG0000000185927
dbx1a / Q9PTU1 / developing brain homeobox 1a / DBX1* / A6NMT0* / P52950* / Homeobox protein DBX1 * / developing brain homeobox 1*ENSDARG0000008639327
barx1 / BARX homeobox 1 / Q9ER42* / Q9HBU1* / Homeobox protein BarH-like 1 *ENSDARG0000000740726
tlx3b / T cell leukemia homeobox 3bENSDARG0000001761526
bsx / Q6R3Q6 / brain-specific homeobox / Q3C1V8* / Q810B3* / Brain-specific homeobox protein homolog *ENSDARG0000006897626
hlx1 / H2.0-like homeo box 1 (Drosophila) / HLX* / Q14774* / Q61670* / H2.0 like homeobox* / H2.0-like homeobox protein *ENSDARG0000000913425
tlx2 / T cell leukemia homeobox 2 / TLX1* / P31314* / T cell leukemia homeobox 1*ENSDARG0000001127325
lbx1a / ladybird homeobox 1a / LBX1* / P52954* / P52955* / ladybird homeobox 1* / Transcription factor LBX1 *ENSDARG0000001832125
barhl2 / BarH-like homeobox 2 / Q8VIB5* / Q9NY43* / BarH-like 2 homeobox protein *ENSDARG0000010436125
barhl1a / BarH-like homeobox 1a / Q9BZE3* / P63157* / BARHL1* / BarH like homeobox 1* / BarH-like 1 homeobox protein *ENSDARG0000003550824
tlx1 / T cell leukemia homeobox 1 / P31314*ENSDARG0000000396523
lbx1b / ladybird homeobox 1b / LBX1* / P52954* / P52955* / ladybird homeobox 1* / Transcription factor LBX1 *ENSDARG0000001861123
nkx6.1 / NK6 homeobox 1 / P78426* / Q99MA9* / Homeobox protein Nkx-6.1 *ENSDARG0000002256923
lbx2 / ladybird homeobox 2ENSDARG0000002513123
nkx6.2 / NK6 homeobox 2 / Q9C056*ENSDARG0000010473523
barhl1b / BarH-like homeobox 1b / Q9BZE3* / P63157* / BARHL1* / BarH like homeobox 1* / BarH-like 1 homeobox protein *ENSDARG0000001901322
barx2 / BARX homeobox 2 / O08686* / Q9UMQ3* / Homeobox protein BarH-like 2 *ENSDARG0000004109822
nkx6.3 / NK6 homeobox 3 / A6NJ46* / Q3UHX8* / Homeobox protein Nkx-6.3 *ENSDARG0000006052920


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030154 cell differentiation IBA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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