ENSDARG00000009134


Danio rerio

Features
Gene ID: ENSDARG00000009134
  
Biological name :hlx1
  
Synonyms : H2.0-like homeo box 1 (Drosophila) / hlx1
  
Possible biological names infered from orthology : H2.0 like homeobox / H2.0-like homeobox protein / HLX / Q14774 / Q61670
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 52195525
Gene end: 52199311
  
Corresponding Affymetrix probe sets: Dr.23762.1.A1_at (Zebrafish Array)   NM_212701_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000116160
Ensembl peptide - ENSDARP00000119935
NCBI entrez gene - 327096     See in Manteia.
RefSeq - NM_212701
RefSeq Peptide - NP_997866
swissprot - B8JMG4
swissprot - B8JMG3
ZFIN ID - ZDB-GENE-030131-5304
Ensembl - ENSDARG00000009134
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HLXENSGALG00000037257Gallus gallus
 HLXENSG00000136630Homo sapiens
 HlxENSMUSG00000039377Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dbx1a / Q9PTU1 / developing brain homeobox 1a / DBX1* / A6NMT0* / P52950* / Homeobox protein DBX1 * / developing brain homeobox 1*ENSDARG0000008639323
dbx1b / developing brain homeobox 1b / DBX1* / P52950* / A6NMT0* / Homeobox protein DBX1 * / developing brain homeobox 1*ENSDARG0000000185922
barx1 / BARX homeobox 1 / Q9ER42* / Q9HBU1* / Homeobox protein BarH-like 1 *ENSDARG0000000740717
nkx6.1 / NK6 homeobox 1 / P78426* / Q99MA9* / Homeobox protein Nkx-6.1 *ENSDARG0000002256917
barx2 / BARX homeobox 2 / O08686* / Q9UMQ3* / Homeobox protein BarH-like 2 *ENSDARG0000004109816
tlx3b / T cell leukemia homeobox 3bENSDARG0000001761515
barhl1b / BarH-like homeobox 1b / Q9BZE3* / P63157* / BARHL1* / BarH like homeobox 1* / BarH-like 1 homeobox protein *ENSDARG0000001901315
nkx6.3 / NK6 homeobox 3 / A6NJ46* / Q3UHX8* / Homeobox protein Nkx-6.3 *ENSDARG0000006052915
barhl2 / BarH-like homeobox 2 / Q8VIB5* / Q9NY43* / BarH-like 2 homeobox protein *ENSDARG0000010436115
nkx6.2 / NK6 homeobox 2 / Q9C056*ENSDARG0000010473515
tlx1 / T cell leukemia homeobox 1 / P31314*ENSDARG0000000396514
lbx2 / ladybird homeobox 2ENSDARG0000002513114
barhl1a / BarH-like homeobox 1a / Q9BZE3* / P63157* / BARHL1* / BarH like homeobox 1* / BarH-like 1 homeobox protein *ENSDARG0000003550814
bsx / Q6R3Q6 / brain-specific homeobox / Q3C1V8* / Q810B3* / Brain-specific homeobox protein homolog *ENSDARG0000006897614
tlx2 / T cell leukemia homeobox 2 / TLX1* / P31314* / T cell leukemia homeobox 1*ENSDARG0000001127313
lbx1a / ladybird homeobox 1a / LBX1* / P52954* / P52955* / ladybird homeobox 1* / Transcription factor LBX1 *ENSDARG0000001832113
HHEX / hematopoietically expressed homeobox / Q03014*ENSDARG0000009823113
lbx1b / ladybird homeobox 1b / LBX1* / P52954* / P52955* / ladybird homeobox 1* / Transcription factor LBX1 *ENSDARG0000001861112


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002040 sprouting angiogenesis IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000084 yolk yolk edematous , abnormal
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 ZFA:0001057 intersegmental vein intersegmental vein blood circulation disrupted , abnormal
intersegmental vein arrested , abnormal
intersegmental vein sprouting angiogenesis delayed , abnormal
intersegmental vein malformed , abnormal
intersegmental vein shortened , abnormal
intersegmental vein sprouting angiogenesis disrupted , abnormal
intersegmental vein cell proliferation decreased occurrence , abnormal
intersegmental vein lacks parts or has fewer parts of type endothelial cell , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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