ENSDARG00000100420


Danio rerio

Features
Gene ID: ENSDARG00000100420
  
Biological name :tpcn2
  
Synonyms : tpcn2 / two pore segment channel 2
  
Possible biological names infered from orthology : Q8BWC0 / Q8NHX9 / Two pore calcium channel protein 2
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 55005229
Gene end: 55051692
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000133679
swissprot - A0A0R4IHY9
ZFIN ID - ZDB-GENE-061103-202
Ensembl - ENSDARG00000100420
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TPCN2ENSGALG00000007550Gallus gallus
 TPCN2ENSG00000162341Homo sapiens
 Tpcn2ENSMUSG00000048677Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tpcn1 / two pore segment channel 1 / Q9EQJ0* / Q9ULQ1* / Two pore calcium channel protein 1 *ENSDARG0000006236221
gb:eh507706 / expressed sequence EH507706ENSDARG0000007895921


Protein motifs (from Interpro)
Interpro ID Name
 IPR005821  Ion transport domain
 IPR028798  Two pore calcium channel protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005245 voltage-gated calcium channel activity IEA
 molecular_functionGO:0072345 NAADP-sensitive calcium-release channel activity IEA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased pigmentation , abnormal
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 ZFA:0000155 somite somite U-shaped , abnormal
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 ZFA:0001056 myotome myotome decreased width , abnormal
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 ZFA:0001114 head head decreased pigmentation , abnormal
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 ZFA:0001115 trunk trunk decreased pigmentation , abnormal
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 ZFA:0005784 striated muscle cell striated muscle cell increased length , abnormal
striated muscle cell decreased width , abnormal
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 ZFA:0009044 blood cell blood cell accumulation heart , abnormal
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 ZFA:0009116 slow muscle cell slow muscle cell decreased amount , abnormal
slow muscle cell sarcomere morphology , abnormal
slow muscle cell skeletal muscle myofibril disorganized , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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