ENSDARG00000100854


Danio rerio

Features
Gene ID: ENSDARG00000100854
  
Biological name :ago4
  
Synonyms : ago4 / argonaute RISC catalytic component 4
  
Possible biological names infered from orthology : argonaute 4, RISC catalytic component / Protein argonaute-4 / Q8CJF8 / Q9HCK5
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 47800550
Gene end: 47832853
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000131528
NCBI entrez gene - 100535764     See in Manteia.
RefSeq - NM_001252559
RefSeq Peptide - NP_001239488
swissprot - K4IAH1
swissprot - A0A0R4IAN2
ZFIN ID - ZDB-GENE-030131-5357
Ensembl - ENSDARG00000100854
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AGO4ENSGALG00000039713Gallus gallus
 AGO4ENSG00000134698Homo sapiens
 Ago4ENSMUSG00000042500Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ago1 / argonaute RISC catalytic component 1 / Q8CJG1* / Q9UL18* / Protein argonaute-1 * / argonaute 1, RISC catalytic component*ENSDARG0000009264483
ago3a / argonaute RISC catalytic component 3a / AGO3* / Q9H9G7* / argonaute 3, RISC catalytic component*ENSDARG0000005988881
ago3b / A3KPK0 / argonaute RISC catalytic component 3b / AGO3* / Q8CJF9* / Q9H9G7* / Protein argonaute-3 * / argonaute 3, RISC catalytic component*ENSDARG0000006307981
ago2 / argonaute RISC catalytic component 2 / Q8CJG0* / Q9UKV8* / Protein argonaute-2 * / argonaute 2, RISC catalytic component*ENSDARG0000006126879
piwil1 / Q8UVX0 / piwi-like RNA-mediated gene silencing 1 / Q96J94* / Q9JMB7* / Piwi-like protein 1 *ENSDARG0000004169922
piwil2 / A2CEI6 / piwi-like RNA-mediated gene silencing 2 / Q8TC59* / Q8CDG1* / Piwi-like protein 2 *ENSDARG0000006260120


Protein motifs (from Interpro)
Interpro ID Name
 IPR003100  PAZ domain
 IPR003165  Piwi domain
 IPR012337  Ribonuclease H-like superfamily
 IPR014811  Argonaute, linker 1 domain
 IPR028604  Protein argonaute-4
 IPR032472  Argonaute linker 2 domain
 IPR032473  Protein argonaute, Mid domain
 IPR032474  Protein argonaute, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0035278 miRNA mediated inhibition of translation IEA
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016442 RISC complex IEA
 cellular_componentGO:0035068 micro-ribonucleoprotein complex IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0035198 miRNA binding IEA


Pathways (from Reactome)
Pathway description
MicroRNA (miRNA) biogenesis
Small interfering RNA (siRNA) biogenesis
Post-transcriptional silencing by small RNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000015829 mov10a / Mov10 RISC complex RNA helicase a / MOV10* / Q9HCE1* / Mov10 RISC complex RNA helicase*  / complex
 ENSDARG00000061177 Q1LXK4 / mov10b.1 / Moloney leukemia virus 10b, tandem duplicate 1 / MOV10* / Q9HCE1* / P23249* / Putative helicase MOV-10 * / Mov10 RISC complex RNA helicase*  / complex
 ENSDARG00000056065 Q1LXK5 / mov10b.2 / Moloney leukemia virus 10b, tandem duplicate 2 / MOV10* / Q9HCE1* / P23249* / Putative helicase MOV-10 * / Mov10 RISC complex RNA helicase*  / complex
 ENSDARG00000076847 tnrc6c1 / trinucleotide repeat containing 6C1 / Q9HCJ0* / TNRC6C* / trinucleotide repeat containing 6C*  / complex
 ENSDARG00000103851 tnrc6c2 / trinucleotide repeat containing 6C2 / Q9HCJ0* / TNRC6C* / trinucleotide repeat containing 6C*  / complex






 

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