ENSG00000122375


Homo sapiens

Features
Gene ID: ENSG00000122375
  
Biological name :OPN4
  
Synonyms : OPN4 / opsin 4 / Q9UHM6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q23.2
Gene start: 86654557
Gene end: 86666848
  
Corresponding Affymetrix probe sets: 234226_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000393132
Ensembl peptide - ENSP00000241891
Ensembl peptide - ENSP00000361141
NCBI entrez gene - 94233     See in Manteia.
OMIM - 606665
RefSeq - XM_017016957
RefSeq - NM_001030015
RefSeq - NM_033282
RefSeq - XM_017016955
RefSeq - XM_017016956
RefSeq Peptide - NP_001025186
RefSeq Peptide - NP_150598
swissprot - Q9UHM6
swissprot - C9JWU6
Ensembl - ENSG00000122375
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 opn4.1ENSDARG00000007553Danio rerio
 opn4aENSDARG00000022098Danio rerio
 opn4bENSDARG00000053929Danio rerio
 OPN4ENSGALG00000001934Gallus gallus
 Opn4ENSMUSG00000021799Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RRH / O14718 / retinal pigment epithelium-derived rhodopsin homologENSG0000018024520
OPN3 / Q9H1Y3 / opsin 3ENSG0000005427719
OPN1SW / P03999 / opsin 1, short wave sensitiveENSG0000012861719
RHO / P08100 / rhodopsinENSG0000016391419
OPN1LW / P04000 / opsin 1, long wave sensitiveENSG0000010207618
OPN5 / Q6U736 / opsin 5ENSG0000012481818
P0DN77 / OPN1MW2 / opsin 1, medium wave sensitive 2ENSG0000016616018
OPN1MW / P04001 / opsin 1, medium wave sensitiveENSG0000026822118
P0DN78 / OPN1MW3 / opsin 1, medium wave sensitive 3ENSG0000026943318


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001760  Opsin
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR027430  Visual pigments (opsins) retinal binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0007602 phototransduction IEA
 biological_processGO:0016056 rhodopsin mediated signaling pathway IEA
 biological_processGO:0018298 protein-chromophore linkage IEA
 biological_processGO:0042752 regulation of circadian rhythm IEA
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0050896 response to stimulus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0097381 photoreceptor disc membrane TAS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005502 11-cis retinal binding IDA
 molecular_functionGO:0008020 G-protein coupled photoreceptor activity IEA
 molecular_functionGO:0009881 photoreceptor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events
Opsins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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