ENSGALG00000008267


Gallus gallus

Features
Gene ID: ENSGALG00000008267
  
Biological name :IL5RA
  
Synonyms : IL5RA / interleukin 5 receptor subunit alpha
  
Possible biological names infered from orthology : P21183 / Q01344
  
Species: Gallus gallus
  
Chr. number: 12
Strand: -1
Band:
Gene start: 18124659
Gene end: 18138869
  
Corresponding Affymetrix probe sets: GgaAffx.5217.1.S1_at (Chicken Array)   GgaAffx.5217.2.S1_at (Chicken Array)   GgaAffx.5217.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000058658
Ensembl peptide - ENSGALP00000042767
NCBI entrez gene - 771801     See in Manteia.
RefSeq - XM_015293144
RefSeq - NM_001256152
RefSeq Peptide - NP_001243081
swissprot - R4GKR1
swissprot - E1C261
Ensembl - ENSGALG00000008267
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il13ra2ENSDARG00000039436Danio rerio
 IL5RAENSG00000091181Homo sapiens
 Il5raENSMUSG00000005364Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IL13RA1 / interleukin 13 receptor subunit alpha 1 / O09030* / P78552*ENSGALG0000004448022
IL13RA2 / interleukin-13 receptor subunit alpha-2 precursor / O88786* / Q14627* / interleukin 13 receptor subunit alpha 2*ENSGALG0000002031619


Protein motifs (from Interpro)
Interpro ID Name
 IPR003532  Short hematopoietin receptor, family 2, conserved site
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR015321  Type I cytokine receptor, cytokine-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002437 inflammatory response to antigenic stimulus IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 biological_processGO:0032674 regulation of interleukin-5 production IEA
 biological_processGO:0071310 cellular response to organic substance IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004896 cytokine receptor activity IEA


Pathways (from Reactome)
Pathway description
Interleukin-3, Interleukin-5 and GM-CSF signaling
RAF/MAP kinase cascade
Interleukin receptor SHC signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004821 PTPN11 / Q90687 / Tyrosine-protein phosphatase non-receptor type 11 / P35235* / Q06124* / protein tyrosine phosphatase, non-receptor type 11*  / complex / reaction
 ENSGALG00000003282 STAT5B / signal transducer and activator of transcription 5B / P42229* / P42232* / P51692* / P42230* / STAT5A* / signal transducer and activator of transcription 5A*  / complex / reaction
 ENSGALG00000008016 GRB2 / growth factor receptor-bound protein 2 / P62993* / Q60631*  / complex / reaction
 ENSGALG00000015027 JAK2 / Janus kinase 2 / O60674*  / reaction / complex
 ENSGALG00000014561 PTPN6 / tyrosine-protein phosphatase non-receptor type 6 / P29350* / P29351* / protein tyrosine phosphatase, non-receptor type 6*  / complex / reaction
 ENSGALG00000002583 PIK3CD / phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform / O00329* / O35904* / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta*  / complex / reaction
 ENSGALG00000004336 INPPL1 / inositol polyphosphate phosphatase like 1 / O15357* / Q6P549* / Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 *  / complex / reaction
 ENSGALG00000008934 PIK3CA / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha / P42336* / P42337* / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform *  / complex / reaction
 ENSGALG00000005505 PIK3CB / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta / P42338* / Q8BTI9* / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform *  / complex / reaction
 ENSGALG00000014786 PIK3R1 / phosphoinositide-3-kinase regulatory subunit 1 / P26450* / P27986*  / complex / reaction
 ENSGALG00000008267 IL5RA / interleukin 5 receptor subunit alpha / P21183* / Q01344*  / complex
 ENSGALG00000039775 SHC1 / SHC adaptor protein 1 / P29353* / P98083* / SHC-transforming protein 1 *  / reaction / complex
 ENSGALG00000031387 YWHAZ / Q5ZKC9 / 14-3-3 protein zeta / P63104* / P63101* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenas...  / complex / reaction
 ENSGALG00000039450 SOS1 / SOS Ras/Rac guanine nucleotide exchange factor 1 / Q07889* / Q62245* / Son of sevenless homolog 1 *  / complex / reaction






 

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