ENSGALG00000003282


Gallus gallus

Features
Gene ID: ENSGALG00000003282
  
Biological name :STAT5B
  
Synonyms : signal transducer and activator of transcription 5B / STAT5B
  
Possible biological names infered from orthology : P42229 / P42230 / P42232 / P51692 / signal transducer and activator of transcription 5A / STAT5A
  
Species: Gallus gallus
  
Chr. number: 27
Strand: -1
Band:
Gene start: 5296817
Gene end: 5306850
  
Corresponding Affymetrix probe sets: Gga.1095.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000052516
Ensembl peptide - ENSGALP00000057979
Ensembl peptide - ENSGALP00000005182
Ensembl peptide - ENSGALP00000047708
NCBI entrez gene - 395556     See in Manteia.
RefSeq - XM_015299592
RefSeq - NM_204779
RefSeq - XM_015299589
RefSeq - XM_015299590
RefSeq - XM_015299591
RefSeq Peptide - NP_990110
swissprot - B9VVJ4
swissprot - F7BQ11
swissprot - A0A1D5P4U6
Ensembl - ENSGALG00000003282
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stat5aENSDARG00000019392Danio rerio
 stat5bENSDARG00000055588Danio rerio
 P42229ENSG00000126561Homo sapiens
 P51692ENSG00000173757Homo sapiens
 P42230ENSMUSG00000004043Mus musculus
 P42232ENSMUSG00000020919Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STAT3 / Q6DV79 / Signal transducer and activator of transcription 3 / P40763* / P42227*ENSGALG0000000326726
STAT4 / signal transducer and activator of transcription 4 / Q14765*ENSGALG0000003308726
STAT1 / signal transducer and activator of transcription 1 / P42224*ENSGALG0000000765125
STAT2 / signal transducer and activator of transcription 2 / P52630*ENSGALG0000003066123


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001217  Transcription factor STAT
 IPR008967  p53-like transcription factor, DNA-binding
 IPR011992  EF-hand domain pair
 IPR012345  STAT transcription factor, DNA-binding, N-terminal
 IPR013799  STAT transcription factor, protein interaction
 IPR013800  STAT transcription factor, all-alpha domain
 IPR013801  STAT transcription factor, DNA-binding
 IPR015988  STAT transcription factor, coiled coil


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA


Pathways (from Reactome)
Pathway description
Nuclear signaling by ERBB4
Interleukin-7 signaling
Signaling by SCF-KIT
Downstream signal transduction
Signaling by Leptin
Interleukin-3, Interleukin-5 and GM-CSF signaling
Interleukin-20 family signaling
Interleukin-15 signaling
Interleukin-9 signaling
Interleukin-2 signaling
Interleukin-21 signaling
Growth hormone receptor signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000249 GH / P08998 / Somatotropin / GH2* / GH1* / CSH1* / CSH2* / CSHL1* / Q14406* / P0DML3* / P0DML2* / P01241* / P01242* / P06880* / growth hormone 1* / growth hormone 2* / chorionic somatomamm...  / complex
 ENSGALG00000003282 STAT5B / signal transducer and activator of transcription 5B / P42229* / P42232* / P51692* / P42230* / STAT5A* / signal transducer and activator of transcription 5A*  / complex / reaction
 ENSGALG00000003267 STAT3 / Q6DV79 / Signal transducer and activator of transcription 3 / P40763* / P42227*  / complex / reaction
 ENSGALG00000007651 STAT1 / signal transducer and activator of transcription 1 / P42224*  / complex / reaction
 ENSGALG00000011031 JAK1 / tyrosine-protein kinase JAK1 / P23458* / Janus kinase 1*  / complex / reaction
 ENSGALG00000019147 IL3RA* / P26951* / P26952* / P15509* / Q00941* / CSF2RA* / interleukin 3 receptor subunit alpha* / colony stimulating factor 2 receptor alpha subunit* / Granulocyte-macrophage colony-stimul...  / complex / reaction
 ENSGALG00000015027 JAK2 / Janus kinase 2 / O60674*  / complex / reaction
 ENSGALG00000013372 IL7R / interleukin 7 receptor / P16871* / P16872* / Interleukin-7 receptor subunit alpha *  / complex
 ENSGALG00000016693 CSF2RA / IL3RA* / P15509* / Q00941* / P26951* / P26952* / interleukin 3 receptor subunit alpha* / colony stimulating factor 2 receptor alpha subunit* / Granulocyte-macrophage colony-stimula...  / complex / reaction
 ENSGALG00000008267 IL5RA / interleukin 5 receptor subunit alpha / P21183* / Q01344*  / complex / reaction
 ENSGALG00000033234 JAK3 / tyrosine-protein kinase JAK3 / P52333* / Janus kinase 3*  / complex / reaction
 ENSGALG00000014855 GHR / growth hormone receptor precursor / P16882* / P10912* / growth hormone receptor* / Growth hormone receptor Growth hormone-binding protein*  / complex
 ENSGALG00000011206 KITLG / Q09108 / Kit ligand Processed kit ligand / Kitl* / P20826* / P21583* / KIT ligand* / Kit ligand Soluble KIT ligand*  / complex / reaction
 ENSGALG00000038634 KIT / Q08156 / Mast/stem cell growth factor receptor Kit / P05532* / P10721* / KIT proto-oncogene receptor tyrosine kinase*  / complex / reaction
 ENSGALG00000003126 ERBB4 / receptor tyrosine-protein kinase erbB-4 / Q15303* / Q61527* / erb-b2 receptor tyrosine kinase 4* / Receptor tyrosine-protein kinase erbB-4 ERBB4 intracellular domain*  / complex / reaction






 

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