ENSGALG00000033087


Gallus gallus

Features
Gene ID: ENSGALG00000033087
  
Biological name :STAT4
  
Synonyms : signal transducer and activator of transcription 4 / STAT4
  
Possible biological names infered from orthology : Q14765
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 7944895
Gene end: 7982542
  
Corresponding Affymetrix probe sets: GgaAffx.4780.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049783
Ensembl peptide - ENSGALP00000054547
NCBI entrez gene - 768406     See in Manteia.
RefSeq - NM_001267555
RefSeq - XM_015289448
RefSeq - XM_015289449
RefSeq Peptide - NP_001254484
swissprot - A0A1D5PNV3
swissprot - A0A1D5PAM0
Ensembl - ENSGALG00000033087
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stat4ENSDARG00000028731Danio rerio
 STAT4ENSG00000138378Homo sapiens
 Stat4ENSMUSG00000062939Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STAT1 / signal transducer and activator of transcription 1 / P42224*ENSGALG0000000765154
STAT3 / Q6DV79 / Signal transducer and activator of transcription 3 / P40763* / P42227*ENSGALG0000000326749
STAT2 / signal transducer and activator of transcription 2 / P52630*ENSGALG0000003066138
STAT5B / signal transducer and activator of transcription 5B / P42229* / P42232* / P51692* / P42230* / STAT5A* / signal transducer and activator of transcription 5A*ENSGALG0000000328228


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001217  Transcription factor STAT
 IPR008967  p53-like transcription factor, DNA-binding
 IPR011992  EF-hand domain pair
 IPR012345  STAT transcription factor, DNA-binding, N-terminal
 IPR013799  STAT transcription factor, protein interaction
 IPR013800  STAT transcription factor, all-alpha domain
 IPR013801  STAT transcription factor, DNA-binding
 IPR015988  STAT transcription factor, coiled coil
 IPR029839  Signal transducer and activator of transcription 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-20 family signaling
Interleukin-35 Signalling
Interleukin-12 signaling
Interleukin-23 signaling
Interleukin-21 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003267 STAT3 / Q6DV79 / Signal transducer and activator of transcription 3 / P40763* / P42227*  / complex / reaction
 ENSGALG00000007651 STAT1 / signal transducer and activator of transcription 1 / P42224*  / complex
 ENSGALG00000014716 IL6ST / interleukin 6 signal transducer / P40189* / Q00560* / Interleukin-6 receptor subunit beta *  / complex
 ENSGALG00000011031 JAK1 / tyrosine-protein kinase JAK1 / P23458* / Janus kinase 1*  / complex / reaction
 ENSGALG00000015027 JAK2 / Janus kinase 2 / O60674*  / complex / reaction
 ENSGALG00000011844 IL21 / interleukin 21 / Q9ES17* / Q9HBE4*  / complex
 ENSGALG00000033087 STAT4 / signal transducer and activator of transcription 4 / Q14765*  / complex / reaction
 ENSGALG00000033234 JAK3 / tyrosine-protein kinase JAK3 / P52333* / Janus kinase 3*  / complex






 

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