ENSGALG00000030661


Gallus gallus

Features
Gene ID: ENSGALG00000030661
  
Biological name :STAT2
  
Synonyms : signal transducer and activator of transcription 2 / STAT2
  
Possible biological names infered from orthology : P52630
  
Species: Gallus gallus
  
Chr. number: 33
Strand: -1
Band:
Gene start: 767595
Gene end: 775109
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000051114
Ensembl peptide - ENSGALP00000052740
Ensembl peptide - ENSGALP00000051677
NCBI entrez gene - 100858732     See in Manteia.
RefSeq - XM_015300282
RefSeq - XM_015300283
RefSeq - XM_015300284
RefSeq - XM_015300285
swissprot - A0A1D5PIV4
swissprot - A0A1D5PEB3
Ensembl - ENSGALG00000030661
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stat2ENSDARG00000031647Danio rerio
 STAT2ENSG00000170581Homo sapiens
 Stat2ENSMUSG00000040033Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STAT1 / signal transducer and activator of transcription 1 / P42224*ENSGALG0000000765133
STAT3 / Q6DV79 / Signal transducer and activator of transcription 3 / P40763* / P42227*ENSGALG0000000326732
STAT4 / signal transducer and activator of transcription 4 / Q14765*ENSGALG0000003308730
STAT5B / signal transducer and activator of transcription 5B / P42229* / P42232* / P51692* / P42230* / STAT5A* / signal transducer and activator of transcription 5A*ENSGALG0000000328220


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001217  Transcription factor STAT
 IPR008967  p53-like transcription factor, DNA-binding
 IPR011992  EF-hand domain pair
 IPR012345  STAT transcription factor, DNA-binding, N-terminal
 IPR013799  STAT transcription factor, protein interaction
 IPR013800  STAT transcription factor, all-alpha domain
 IPR013801  STAT transcription factor, DNA-binding
 IPR015988  STAT transcription factor, coiled coil


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001932 regulation of protein phosphorylation IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0060337 type I interferon signaling pathway IEA
 biological_processGO:0090140 regulation of mitochondrial fission IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0044389 ubiquitin-like protein ligase binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-20 family signaling
Interferon alpha/beta signaling
Regulation of IFNA signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004821 PTPN11 / Q90687 / Tyrosine-protein phosphatase non-receptor type 11 / P35235* / Q06124* / protein tyrosine phosphatase, non-receptor type 11*  / reaction
 ENSGALG00000008010 PTPN1 / tyrosine-protein phosphatase non-receptor type 1 / P18031* / P35821* / protein tyrosine phosphatase, non-receptor type 1*  / reaction
 ENSGALG00000007651 STAT1 / signal transducer and activator of transcription 1 / P42224*  / complex / reaction
 ENSGALG00000007158 SOCS1 / suppressor of cytokine signaling 1 / O15524* / O35716*  / complex
 ENSGALG00000011031 JAK1 / tyrosine-protein kinase JAK1 / P23458* / Janus kinase 1*  / complex / reaction
 ENSGALG00000015062 IFNK* / IFNA6* / IFNA7* / IFNA8* / Ifna9* / Ifnab* / IFNW1* / IFNA2* / IFNA4* / IFNA1* / IFNA5* / Q9P0W0* / IFNA10* / Ifna11* / Ifna12* / IFNA13* / IFNA14* / Ifna15* / IFNA16* / IFNA17* / I...  / complex / reaction
 ENSGALG00000014561 PTPN6 / tyrosine-protein phosphatase non-receptor type 6 / P29350* / P29351* / protein tyrosine phosphatase, non-receptor type 6*  / reaction
 ENSGALG00000030661 STAT2 / signal transducer and activator of transcription 2 / P52630*  / complex / reaction






 

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