ENSGALG00000010858


Gallus gallus

Features
Gene ID: ENSGALG00000010858
  
Biological name :LRP2
  
Synonyms : LDL receptor related protein 2 / LRP2
  
Possible biological names infered from orthology : A2ARV4 / low density lipoprotein receptor-related protein 2 / P98164
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 18831986
Gene end: 18938041
  
Corresponding Affymetrix probe sets: Gga.17373.1.S1_s_at (Chicken Array)   GgaAffx.23355.1.S1_at (Chicken Array)   GgaAffx.23355.2.S1_at (Chicken Array)   GgaAffx.23355.3.S1_s_at (Chicken Array)   GgaAffx.23355.5.S1_s_at (Chicken Array)   GgaAffx.23355.6.S1_at (Chicken Array)   GgaAffx.23355.6.S1_s_at (Chicken Array)   GgaAffx.6861.1.S1_s_at (Chicken Array)   GgaAffx.6862.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000017630
NCBI entrez gene - 424168     See in Manteia.
RefSeq - XM_004942764
RefSeq - XM_004942765
RefSeq - XM_004942766
RefSeq - XM_015289664
RefSeq - XM_015289665
RefSeq - XM_015289666
RefSeq - XM_004942763
swissprot - F1NJS9
Ensembl - ENSGALG00000010858
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrp2aENSDARG00000102506Danio rerio
 LRP2ENSG00000081479Homo sapiens
 Lrp2ENSMUSG00000027070Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRP1B / LDL receptor related protein 1B / Q9NZR2*ENSGALG0000001240734
LRP4 / LDL receptor related protein 4 / O75096* / Q8VI56* / Low-density lipoprotein receptor-related protein 4 *ENSGALG0000003218115
LRP5 / low-density lipoprotein receptor-related protein 5 precursor / O75197* / Q91VN0* / LDL receptor related protein 5* / Low-density lipoprotein receptor-related protein 5 *ENSGALG0000002953312
LRP6 / LDL receptor related protein 6 / O75581*ENSGALG0000003150312
Gm19410*ENSGALG000000231729
VLDLR / P98165 / Very low-density lipoprotein receptor / P98155* / P98156*ENSGALG000000101667
LRP8 / low-density lipoprotein receptor-related protein 8 precursor / Q14114* / Q924X6* / LDL receptor related protein 8* / Low-density lipoprotein receptor-related protein 8 *ENSGALG000000106927


Protein motifs (from Interpro)
Interpro ID Name
 IPR000033  LDLR class B repeat
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site
 IPR026823  Complement Clr-like EGF domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0003139 secondary heart field specification IEA
 biological_processGO:0003148 outflow tract septum morphogenesis IEA
 biological_processGO:0003223 ventricular compact myocardium morphogenesis IEA
 biological_processGO:0003281 ventricular septum development IEA
 biological_processGO:0006766 vitamin metabolic process IEA
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0030001 metal ion transport IEA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0035904 aorta development IEA
 biological_processGO:0050769 positive regulation of neurogenesis IEA
 biological_processGO:0060068 vagina development IEA
 biological_processGO:0060976 coronary vasculature development IEA
 biological_processGO:0060982 coronary artery morphogenesis IEA
 biological_processGO:0061156 pulmonary artery morphogenesis IEA
 biological_processGO:0070447 positive regulation of oligodendrocyte progenitor proliferation IEA
 biological_processGO:0140058 neuron projection arborization IEA
 biological_processGO:1904447 folate import across plasma membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005903 brush border IEA
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030139 endocytic vesicle IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031526 brush border membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 cellular_componentGO:0045177 apical part of cell IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Vitamin D (calciferol) metabolism
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008704 CUBN / cubilin / O60494* / Q9JLB4*  / reaction






 

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