ENSGALG00000032181


Gallus gallus

Features
Gene ID: ENSGALG00000032181
  
Biological name :LRP4
  
Synonyms : LDL receptor related protein 4 / LRP4
  
Possible biological names infered from orthology : Low-density lipoprotein receptor-related protein 4 / O75096 / Q8VI56
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 23347084
Gene end: 23385831
  
Corresponding Affymetrix probe sets: Gga.17628.1.S1_at (Chicken Array)   GgaAffx.5238.1.S1_s_at (Chicken Array)   GgaAffx.5238.2.S1_s_at (Chicken Array)   GgaAffx.5238.5.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053310
NCBI entrez gene - 423189     See in Manteia.
RefSeq - XM_004941584
RefSeq - XM_004941585
RefSeq - XM_421114
swissprot - A0A1D5PKF3
Ensembl - ENSGALG00000032181
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01071171.1ENSDARG00000116353Danio rerio
 LRP4ENSG00000134569Homo sapiens
 Lrp4ENSMUSG00000027253Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRP2 / LDL receptor related protein 2 / A2ARV4* / P98164* / low density lipoprotein receptor-related protein 2*ENSGALG0000001085837
LRP1B / LDL receptor related protein 1B / Q9NZR2*ENSGALG0000001240733
LRP6 / LDL receptor related protein 6 / O75581*ENSGALG0000003150332
LRP5 / low-density lipoprotein receptor-related protein 5 precursor / O75197* / Q91VN0* / LDL receptor related protein 5* / Low-density lipoprotein receptor-related protein 5 *ENSGALG0000002953331
VLDLR / P98165 / Very low-density lipoprotein receptor / P98155* / P98156*ENSGALG0000001016616
LRP8 / low-density lipoprotein receptor-related protein 8 precursor / Q14114* / Q924X6* / LDL receptor related protein 8* / Low-density lipoprotein receptor-related protein 8 *ENSGALG0000001069216
Gm19410*ENSGALG0000002317212


Protein motifs (from Interpro)
Interpro ID Name
 IPR000033  LDLR class B repeat
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site
 IPR026823  Complement Clr-like EGF domain
 IPR030799  Low-density lipoprotein receptor-related protein 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0001932 regulation of protein phosphorylation IEA
 biological_processGO:0001942 hair follicle development IEA
 biological_processGO:0008104 protein localization IEA
 biological_processGO:0009953 dorsal/ventral pattern formation IEA
 biological_processGO:0009954 proximal/distal pattern formation IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 biological_processGO:0030279 negative regulation of ossification IEA
 biological_processGO:0030326 embryonic limb morphogenesis IEA
 biological_processGO:0030509 BMP signaling pathway IEA
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IEA
 biological_processGO:0042733 embryonic digit morphogenesis IEA
 biological_processGO:0043113 receptor clustering IEA
 biological_processGO:0048513 animal organ development IEA
 biological_processGO:0048856 anatomical structure development IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0050771 negative regulation of axonogenesis IEA
 biological_processGO:0051124 synaptic growth at neuromuscular junction IEA
 biological_processGO:0060173 limb development IEA
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0071340 skeletal muscle acetylcholine-gated channel clustering IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0097104 postsynaptic membrane assembly IEA
 biological_processGO:0097105 presynaptic membrane assembly IEA
 biological_processGO:1901631 positive regulation of presynaptic membrane organization IEA
 biological_processGO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031594 neuromuscular junction IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0030971 receptor tyrosine kinase binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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