ENSGALG00000011259


Gallus gallus

Features
Gene ID: ENSGALG00000011259
  
Biological name :RPE65
  
Synonyms : Q9YGX2 / Retinoid isomerohydrolase / RPE65
  
Possible biological names infered from orthology : Q16518 / Q91ZQ5 / RPE65, retinoid isomerohydrolase
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 28872046
Gene end: 28878904
  
Corresponding Affymetrix probe sets: Gga.408.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018351
NCBI entrez gene - 395700     See in Manteia.
RefSeq - XM_015290971
RefSeq - NM_204884
RefSeq - XM_015290969
RefSeq - XM_015290970
RefSeq - XM_015290966
RefSeq - XM_015290967
RefSeq Peptide - NP_990215
swissprot - Q9YGX2
Ensembl - ENSGALG00000011259
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A9C3R8ENSDARG00000054420Danio rerio
 A9C3R9ENSDARG00000094752Danio rerio
 Q6PBW5ENSDARG00000007480Danio rerio
 RPE65ENSG00000116745Homo sapiens
 Rpe65ENSMUSG00000028174Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BCO2 / beta-carotene oxygenase 2 / Q99NF1* / Q9BYV7* / Beta,beta-carotene 9,10-oxygenase *ENSGALG0000000786836
BCO1 / Q9I993 / Beta,beta-carotene 15,15-dioxygenase / Q9HAY6* / Q9JJS6* / beta-carotene oxygenase 1*ENSGALG0000000540835


Protein motifs (from Interpro)
Interpro ID Name
 IPR004294  Carotenoid oxygenase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001895 retina homeostasis IEA
 biological_processGO:0007468 regulation of rhodopsin gene expression IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0008286 insulin receptor signaling pathway IEA
 biological_processGO:0042572 retinol metabolic process IEA
 biological_processGO:0042574 retinal metabolic process IEA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0050908 detection of light stimulus involved in visual perception IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060041 retina development in camera-type eye IEA
 biological_processGO:0060042 retina morphogenesis in camera-type eye IEA
 biological_processGO:0071257 cellular response to electrical stimulus IEA
 biological_processGO:1901827 zeaxanthin biosynthetic process IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane ISS
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0001786 phosphatidylserine binding ISS
 molecular_functionGO:0004744 retinal isomerase activity IEA
 molecular_functionGO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0031210 phosphatidylcholine binding ISS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0052884 all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity IEA
 molecular_functionGO:0052885 all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity IDA
 molecular_functionGO:1901612 cardiolipin binding ISS


Pathways (from Reactome)
Pathway description
The canonical retinoid cycle in rods (twilight vision)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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