ENSDARG00000054420


Danio rerio

Features
Gene ID: ENSDARG00000054420
  
Biological name :rpe65c
  
Synonyms : A9C3R8 / retinal pigment epithelium-specific protein 65c / rpe65c
  
Possible biological names infered from orthology : Q16518 / Q91ZQ5 / Retinoid isomerohydrolase / RPE65 / RPE65, retinoid isomerohydrolase
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 16702106
Gene end: 16712255
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000151304
Ensembl peptide - ENSDARP00000153315
Ensembl peptide - ENSDARP00000071071
NCBI entrez gene - 100004076     See in Manteia.
RefSeq - NM_001113653
RefSeq Peptide - NP_001107125
swissprot - A9C3R8
ZFIN ID - ZDB-GENE-081104-505
Ensembl - ENSDARG00000054420
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RPE65ENSGALG00000011259Gallus gallus
 RPE65ENSG00000116745Homo sapiens
 Rpe65ENSMUSG00000028174Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A9C3R9 / rpe65b / retinal pigment epithelium-specific protein 65b / RPE65* / Q91ZQ5* / Q16518* / Retinoid isomerohydrolase * / RPE65, retinoid isomerohydrolase*ENSDARG0000009475296
rpe65a / Q6PBW5 / retinal pigment epithelium-specific protein 65a / RPE65* / Q16518* / RPE65, retinoid isomerohydrolase*ENSDARG0000000748078
bco2a / beta-carotene oxygenase 2a / BCO2* / Q99NF1* / Q9BYV7* / beta-carotene oxygenase 2* / Beta,beta-carotene 9,10-oxygenase *ENSDARG0000005572236
bco2l / beta-carotene 15, 15-dioxygenase 2, like / BCO2* / Q9BYV7* / Q99NF1* / beta-carotene oxygenase 2* / Beta,beta-carotene 9,10-oxygenase *ENSDARG0000002762035
bco1l / beta-carotene oxygenase 1, like / BCO1* / Q9HAY6* / Q9JJS6* / beta-carotene oxygenase 1* / Beta,beta-carotene 15,15-dioxygenase *ENSDARG0000010365935
bco2b / beta-carotene oxygenase 2b / BCO2* / Q99NF1* / Q9BYV7* / beta-carotene oxygenase 2* / Beta,beta-carotene 9,10-oxygenase *ENSDARG0000004171534
bco1 / beta-carotene oxygenase 1 / Q9HAY6* / Q9JJS6* / Beta,beta-carotene 15,15-dioxygenase *ENSDARG0000010425632


Protein motifs (from Interpro)
Interpro ID Name
 IPR004294  Carotenoid oxygenase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042572 retinol metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IDA
 molecular_functionGO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050251 retinol isomerase activity IDA
 molecular_functionGO:0052884 all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity IEA
 molecular_functionGO:0052885 all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity IEA


Pathways (from Reactome)
Pathway description
The canonical retinoid cycle in rods (twilight vision)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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