ENSDARG00000027620


Danio rerio

Features
Gene ID: ENSDARG00000027620
  
Biological name :bco2l
  
Synonyms : bco2l / beta-carotene 15, 15-dioxygenase 2, like
  
Possible biological names infered from orthology : BCO2 / Beta,beta-carotene 9,10-oxygenase / beta-carotene oxygenase 2 / Q99NF1 / Q9BYV7
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 26121393
Gene end: 26130527
  
Corresponding Affymetrix probe sets: Dr.9838.1.S1_at (Zebrafish Array)   NM_131799_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000013052
NCBI entrez gene - 84041     See in Manteia.
RefSeq - NM_131799
RefSeq Peptide - NP_571874
swissprot - A2BGP6
ZFIN ID - ZDB-GENE-010509-1
Ensembl - ENSDARG00000027620
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BCO2ENSGALG00000007868Gallus gallus
 BCO2ENSG00000197580Homo sapiens
 Bco2ENSMUSG00000032066Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
bco2b / beta-carotene oxygenase 2b / BCO2* / Q99NF1* / Q9BYV7* / beta-carotene oxygenase 2* / Beta,beta-carotene 9,10-oxygenase *ENSDARG0000004171560
bco2a / beta-carotene oxygenase 2a / BCO2* / Q99NF1* / Q9BYV7* / beta-carotene oxygenase 2* / Beta,beta-carotene 9,10-oxygenase *ENSDARG0000005572260
bco1 / beta-carotene oxygenase 1 / Q9HAY6* / Q9JJS6* / Beta,beta-carotene 15,15-dioxygenase *ENSDARG0000010425640
bco1l / beta-carotene oxygenase 1, like / BCO1* / Q9HAY6* / Q9JJS6* / beta-carotene oxygenase 1* / Beta,beta-carotene 15,15-dioxygenase *ENSDARG0000010365937
A9C3R8 / rpe65c / retinal pigment epithelium-specific protein 65c / RPE65* / Q91ZQ5* / Q16518* / Retinoid isomerohydrolase * / RPE65, retinoid isomerohydrolase*ENSDARG0000005442034
A9C3R9 / rpe65b / retinal pigment epithelium-specific protein 65b / RPE65* / Q91ZQ5* / Q16518* / Retinoid isomerohydrolase * / RPE65, retinoid isomerohydrolase*ENSDARG0000009475234
rpe65a / Q6PBW5 / retinal pigment epithelium-specific protein 65a / RPE65* / Q16518* / RPE65, retinoid isomerohydrolase*ENSDARG0000000748033


Protein motifs (from Interpro)
Interpro ID Name
 IPR004294  Carotenoid oxygenase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0005739 mitochondrion IDA
 molecular_functionGO:0010437 9,10 (9", 10")-carotenoid-cleaving dioxygenase activity IDA
 molecular_functionGO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Retinoid metabolism and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood desaturated red , abnormal
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 ZFA:0000114 heart heart nucleate erythrocyte decreased amount , abnormal
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 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
nucleate erythrocyte apoptotic , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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