ENSDARG00000007480


Danio rerio

Features
Gene ID: ENSDARG00000007480
  
Biological name :rpe65a
  
Synonyms : Q6PBW5 / retinal pigment epithelium-specific protein 65a / rpe65a
  
Possible biological names infered from orthology : Q16518 / Q91ZQ5 / Retinoid isomerohydrolase / RPE65 / RPE65, retinoid isomerohydrolase
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 1428696
Gene end: 1443692
  
Corresponding Affymetrix probe sets: Dr.12451.1.S1_at (Zebrafish Array)   Dr.12451.2.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000017189
NCBI entrez gene - 393724     See in Manteia.
swissprot - Q6PBW5
ZFIN ID - ZDB-GENE-040426-1717
Ensembl - ENSDARG00000007480
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RPE65ENSGALG00000011259Gallus gallus
 RPE65ENSG00000116745Homo sapiens
 Rpe65ENSMUSG00000028174Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A9C3R8 / rpe65c / retinal pigment epithelium-specific protein 65c / RPE65* / Q91ZQ5* / Q16518* / Retinoid isomerohydrolase * / RPE65, retinoid isomerohydrolase*ENSDARG0000005442078
A9C3R9 / rpe65b / retinal pigment epithelium-specific protein 65b / RPE65* / Q91ZQ5* / Q16518* / Retinoid isomerohydrolase * / RPE65, retinoid isomerohydrolase*ENSDARG0000009475277
bco2l / beta-carotene 15, 15-dioxygenase 2, like / BCO2* / Q9BYV7* / Q99NF1* / beta-carotene oxygenase 2* / Beta,beta-carotene 9,10-oxygenase *ENSDARG0000002762034
bco2b / beta-carotene oxygenase 2b / BCO2* / Q99NF1* / Q9BYV7* / beta-carotene oxygenase 2* / Beta,beta-carotene 9,10-oxygenase *ENSDARG0000004171533
bco2a / beta-carotene oxygenase 2a / BCO2* / Q99NF1* / Q9BYV7* / beta-carotene oxygenase 2* / Beta,beta-carotene 9,10-oxygenase *ENSDARG0000005572233
bco1l / beta-carotene oxygenase 1, like / BCO1* / Q9HAY6* / Q9JJS6* / beta-carotene oxygenase 1* / Beta,beta-carotene 15,15-dioxygenase *ENSDARG0000010365933
bco1 / beta-carotene oxygenase 1 / Q9HAY6* / Q9JJS6* / Beta,beta-carotene 15,15-dioxygenase *ENSDARG0000010425631


Protein motifs (from Interpro)
Interpro ID Name
 IPR004294  Carotenoid oxygenase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0042572 retinol metabolic process IEA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0052884 all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity IEA
 molecular_functionGO:0052885 all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity IEA


Pathways (from Reactome)
Pathway description
The canonical retinoid cycle in rods (twilight vision)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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