ENSGALG00000014918


Gallus gallus

Features
Gene ID: ENSGALG00000014918
  
Biological name :RFX6
  
Synonyms : regulatory factor X6 / RFX6
  
Possible biological names infered from orthology : DNA-binding protein RFX6 / Q8C7R7 / Q8HWS3
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 63859412
Gene end: 63892453
  
Corresponding Affymetrix probe sets: GgaAffx.9471.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000024015
NCBI entrez gene - 421737     See in Manteia.
RefSeq - XM_015284589
swissprot - E1C4M7
Ensembl - ENSGALG00000014918
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rfx6ENSDARG00000041702Danio rerio
 RFX6ENSG00000185002Homo sapiens
 Rfx6ENSMUSG00000019900Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RFX4 / regulatory factor X4 / Q33E94* / Q7TNK1* / Transcription factor RFX4 *ENSGALG0000001264729
RFX2 / regulatory factor X2 / P48378* / P48379* / DNA-binding protein RFX2 *ENSGALG0000000177319
RFX3 / regulatory factor X3 / P48380* / P48381* / Transcription factor RFX3 *ENSGALG0000001017919
RFX8 / RFX family member 8, lacking RFX DNA binding domain / D3YU81* / Q6ZV50* / DNA-binding protein RFX8 *ENSGALG0000004538814
RFX7 / regulatory factor X7 / Q2KHR2*ENSGALG0000004189610
RFX5 / regulatory factor X5 / P48382* / Q9JL61* / Mus musculus regulatory factor X, 5 (influences HLA class II expression) (Rfx5), transcript variant 2, mRNA.*ENSGALG000000008367


Protein motifs (from Interpro)
Interpro ID Name
 IPR003150  DNA-binding RFX-type winged-helix domain
 IPR011991  ArsR-like helix-turn-helix domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003309 type B pancreatic cell differentiation IEA
 biological_processGO:0003310 pancreatic A cell differentiation IEA
 biological_processGO:0003311 pancreatic D cell differentiation IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0031018 endocrine pancreas development IEA
 biological_processGO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0050796 regulation of insulin secretion IEA
 biological_processGO:0090104 pancreatic epsilon cell differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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