ENSGALG00000015466


Gallus gallus

Features
Gene ID: ENSGALG00000015466
  
Biological name :SIM1
  
Synonyms : SIM1 / single-minded family bHLH transcription factor 1
  
Possible biological names infered from orthology : P81133 / Q61045 / Single-minded homolog 1
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 71185380
Gene end: 71225432
  
Corresponding Affymetrix probe sets: Gga.668.1.S1_s_at (Chicken Array)   GgaAffx.24686.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000024893
NCBI entrez gene - 396129     See in Manteia.
RefSeq - XM_004940356
RefSeq - XM_004940357
swissprot - E1C5G3
Ensembl - ENSGALG00000015466
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sim1aENSDARG00000023316Danio rerio
 sim1bENSDARG00000013789Danio rerio
 SIM1ENSG00000112246Homo sapiens
 Sim1ENSMUSG00000019913Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SIM2 / single-minded family bHLH transcription factor 2 / Q14190* / Q61079* / Single-minded homolog 2 *ENSGALG0000001604452
NPAS3 / neuronal PAS domain protein 3 / Q8IXF0*ENSGALG0000002902228
EPAS1 / endothelial PAS domain protein 1 / P97481* / Q99814* / Endothelial PAS domain-containing protein 1 *ENSGALG0000001000523
HIF1A / hypoxia-inducible factor 1-alpha / Q16665* / Q61221* / hypoxia inducible factor 1 alpha subunit*ENSGALG0000001187023
ARNT / aryl hydrocarbon receptor nuclear translocator / P27540* / P53762*ENSGALG0000000075115
ARNTL / Q9I8T7 / Aryl hydrocarbon receptor nuclear translocator-like protein 1 / Q9WTL8* / O00327* / aryl hydrocarbon receptor nuclear translocator like* / Mus musculus aryl hydrocarbon re...ENSGALG0000000537814
ARNT2 / aryl hydrocarbon receptor nuclear translocator 2 / Q61324* / Q9HBZ2*ENSGALG0000000644514
ARNTL2 / aryl hydrocarbon receptor nuclear translocator-like protein 2 / Q2VPD4* / Q8WYA1* / aryl hydrocarbon receptor nuclear translocator like 2*ENSGALG0000001409614
NPAS2 / neuronal PAS domain-containing protein 2 / Q99743* / neuronal PAS domain protein 2*ENSGALG0000001677414
CLOCK / circadian locomoter output cycles protein kaput isoform 1 / O08785* / O15516* / clock circadian regulator* / Circadian locomoter output cycles protein kaput *ENSGALG0000001379313
ENSGALG0000000906312


Protein motifs (from Interpro)
Interpro ID Name
 IPR000014  PAS domain
 IPR001610  PAC motif
 IPR010578  Single-minded, C-terminal
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR013655  PAS fold-3
 IPR013767  PAS fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001657 ureteric bud development IEA
 biological_processGO:0001822 kidney development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0007399 nervous system development IBA
 biological_processGO:0072179 nephric duct formation IMP
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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