ENSGALG00000017179


Gallus gallus

Features
Gene ID: ENSGALG00000017179
  
Biological name :PDGFD
  
Synonyms : PDGFD / platelet derived growth factor D
  
Possible biological names infered from orthology : Mus musculus platelet-derived growth factor, D polypeptide (Pdgfd), transcript variant 2, mRNA. / Q925I7 / Q9GZP0
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 181945830
Gene end: 182085856
  
Corresponding Affymetrix probe sets: Gga.16041.1.S1_at (Chicken Array)   Gga.5879.1.S1_at (Chicken Array)   Gga.9675.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000029435
NCBI entrez gene - 418978     See in Manteia.
RefSeq - XM_015278147
RefSeq - NM_001277811
RefSeq - XM_015278141
RefSeq - XM_015278143
RefSeq Peptide - NP_001264740
swissprot - F1NPV1
Ensembl - ENSGALG00000017179
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdgfdENSDARG00000077677Danio rerio
 PDGFDENSG00000170962Homo sapiens
 PdgfdENSMUSG00000032006Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDGFC / Q9I946 / Platelet-derived growth factor C Platelet-derived growth factor C, latent form Platelet-derived growth factor C, receptor-binding form / Q9NRA1* / Q8CI19* / platelet derive...ENSGALG0000000937841


Protein motifs (from Interpro)
Interpro ID Name
 IPR000072  PDGF/VEGF domain
 IPR000859  CUB domain
 IPR027123  Platelet-derived growth factor D
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007596 blood coagulation IBA
 biological_processGO:0008284 positive regulation of cell proliferation IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IBA
 biological_processGO:0030335 positive regulation of cell migration IBA
 biological_processGO:0031954 positive regulation of protein autophosphorylation IBA
 biological_processGO:0043406 positive regulation of MAP kinase activity IBA
 biological_processGO:0048008 platelet-derived growth factor receptor signaling pathway IBA
 biological_processGO:0050730 regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071230 cellular response to amino acid stimulus IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005161 platelet-derived growth factor receptor binding IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
Signaling by PDGF


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004293 LPA* / PLG* / P00747* / P08519* / P20918* / plasminogen* / lipoprotein(a)* / Plasminogen Plasmin heavy chain A Activation peptide Angiostatin Plasmin heavy chain A, short form Plasmin light chain B*  / reaction
 ENSGALG00000003709 PLAT / plasminogen activator, tissue type / P00750* / P11214* / Tissue-type plasminogen activator Tissue-type plasminogen activator chain A Tissue-type plasminogen activator chain B*  / reaction
 ENSGALG00000017179 PDGFD / platelet derived growth factor D / Q925I7* / Q9GZP0* / Mus musculus platelet-derived growth factor, D polypeptide (Pdgfd), transcript variant 2, mRNA.*  / complex
 ENSGALG00000028886 LPA* / PLG* / P00747* / P08519* / P20918* / plasminogen* / lipoprotein(a)* / Plasminogen Plasmin heavy chain A Activation peptide Angiostatin Plasmin heavy chain A, short form Plasmin light chain B*  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr