ENSGALG00000033941


Gallus gallus
bindingRORCnuclearreceptortranscriptionhormonednaactivitysequence-specificzincrnapolymeraseiipathwayfingerregulationdna-templatedsignalingsteroidproximalpromoterfactorionligand-bindingdomainreceptor-typerornhrgata-typeintracellularcellular

Features
Gene ID: ENSGALG00000033941
  
Biological name :RORC
  
Synonyms : RAR related orphan receptor C / RORC
  
Possible biological names infered from orthology : Nuclear receptor ROR-gamma / P51449 / P51450
  
Species: Gallus gallus
  
Chr. number: 25
Strand: -1
Band:
Gene start: 2868268
Gene end: 2872192
  
Corresponding Affymetrix probe sets: GgaAffx.640.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049570
NCBI entrez gene - 777355     See in Manteia.
RefSeq - XM_015280013
swissprot - A0A1D5PA12
Ensembl - ENSGALG00000033941
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rorcENSDARG00000087195Danio rerio
 RORCENSG00000143365Homo sapiens
 RorcENSMUSG00000028150Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RORA / nuclear receptor ROR-alpha / P51448* / P35398* / RAR related orphan receptor A* / RAR-related orphan receptor alpha*ENSGALG0000000375944
RORB / RAR related orphan receptor B / Q8R1B8* / Q92753* / Nuclear receptor ROR-beta *ENSGALG0000001515042
ENSGALG0000000103541
NR1D2 / nuclear receptor subfamily 1 group D member 2 / Q14995* / Q60674*ENSGALG0000001129126
PPARD / peroxisome proliferator-activated receptor delta / P35396* / Q03181*ENSGALG0000000258822
PPARG / peroxisome proliferator activated receptor gamma / P37231*ENSGALG0000000497422
PPARA / peroxisome proliferator-activated receptor alpha / P23204* / Q07869*ENSGALG0000004147022
NR5A2 / nuclear receptor subfamily 5 group A member 2 / O00482* / P45448*ENSGALG0000000218218
NR6A1 / nuclear receptor subfamily 6 group A member 1 / Q15406* / Q64249*ENSGALG0000000107317
NR5A1 / steroidogenic factor 1 / P33242* / Q13285* / nuclear receptor subfamily 5 group A member 1*ENSGALG0000000108016


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR003079  Nuclear receptor ROR
 IPR013088  Zinc finger, NHR/GATA-type


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to chemicalresponse to endogenous stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to chemicalresponse to endogenous stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to chemicalresponse to endogenous stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to chemicalresponse to endogenous stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to chemicalresponse to endogenous stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to chemicalresponse to endogenous stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to chemicalresponse to endogenous stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to chemicalresponse to endogenous stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to chemicalresponse to endogenous stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusresponse to chemicalresponse to endogenous stimulusnitrogen compounitrogen compound metabolic processbiosynthetic prbiosynthetic processcellular metabocellular metabolic processprimary metabolprimary metabolic processorganic substanorganic substance metabolic processcell communicatcell communicationcellular responcellular response to stimulusresponse to cheresponse to chemicalresponse to endresponse to endogenous stimulus
organic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compoundorganic cyclic compound bindingheterocyclic compound bheterocyclic compound bindingDNA-binding transcriptiDNA-binding transcription factor activitysignaling receptor actisignaling receptor activitylipid bindinglipid bindingion bindingion binding
cellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0036315 cellular response to sterol IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016604 nuclear body IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0008142 oxysterol binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0098531 transcription factor activity, direct ligand regulated sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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