ENSMUSG00000005069


Mus musculus

Features
Gene ID: ENSMUSG00000005069
  
Biological name :Pex5
  
Synonyms : O09012 / Peroxisomal targeting signal 1 receptor / Pex5
  
Possible biological names infered from orthology : P50542 / peroxisomal biogenesis factor 5
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: F2
Gene start: 124396816
Gene end: 124415067
  
Corresponding Affymetrix probe sets: 10547701 (MoGene1.0st)   1422063_a_at (Mouse Genome 430 2.0 Array)   1426770_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000079398
Ensembl peptide - ENSMUSP00000108150
Ensembl peptide - ENSMUSP00000108151
Ensembl peptide - ENSMUSP00000049132
Ensembl peptide - ENSMUSP00000108149
NCBI entrez gene - 19305     See in Manteia.
MGI - MGI:1098808
RefSeq - XM_017321462
RefSeq - NM_001277330
RefSeq - NM_001277805
RefSeq - NM_008995
RefSeq - NM_175933
RefSeq - XM_006505758
RefSeq - XM_006505759
RefSeq Peptide - NP_033021
RefSeq Peptide - NP_787947
RefSeq Peptide - NP_001264259
RefSeq Peptide - NP_001264734
swissprot - O09012
swissprot - D3Z600
Ensembl - ENSMUSG00000005069
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pex5ENSDARG00000070654Danio rerio
 PEX5ENSGALG00000014683Gallus gallus
 PEX5ENSG00000139197Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pex5l / Q8C437 / PEX5-related protein / Q8IYB4* / peroxisomal biogenesis factor 5 like*ENSMUSG0000002767437


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR023392  Mitochondrial outer membrane translocase complex, Tom20 domain superfamily
 IPR024111  Peroxisomal targeting signal 1 receptor family
 IPR024113  Peroxisomal targeting signal 1 receptor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000038 very long-chain fatty acid metabolic process IMP
 biological_processGO:0001764 neuron migration IMP
 biological_processGO:0006625 protein targeting to peroxisome TAS
 biological_processGO:0006635 fatty acid beta-oxidation IMP
 biological_processGO:0007005 mitochondrion organization IMP
 biological_processGO:0007006 mitochondrial membrane organization IMP
 biological_processGO:0007029 endoplasmic reticulum organization IMP
 biological_processGO:0007031 peroxisome organization IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016558 protein import into peroxisome matrix IMP
 biological_processGO:0016560 protein import into peroxisome matrix, docking ISO
 biological_processGO:0016561 protein import into peroxisome matrix, translocation ISO
 biological_processGO:0021795 cerebral cortex cell migration IMP
 biological_processGO:0021895 cerebral cortex neuron differentiation IMP
 biological_processGO:0040018 positive regulation of multicellular organism growth IMP
 biological_processGO:0044255 cellular lipid metabolic process IMP
 biological_processGO:0045046 protein import into peroxisome membrane ISO
 biological_processGO:0048468 cell development IMP
 biological_processGO:0050905 neuromuscular process IMP
 biological_processGO:0051262 protein tetramerization ISO
 biological_processGO:1901094 negative regulation of protein homotetramerization ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005777 peroxisome ISO
 cellular_componentGO:0005778 peroxisomal membrane IBA
 cellular_componentGO:0005782 peroxisomal matrix ISO
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane ISO
 molecular_functionGO:0000268 peroxisome targeting sequence binding TAS
 molecular_functionGO:0005052 peroxisome matrix targeting signal-1 binding ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008022 protein C-terminus binding ISO
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0031267 small GTPase binding ISO
 molecular_functionGO:0047485 protein N-terminus binding ISO


Pathways (from Reactome)
Pathway description
E3 ubiquitin ligases ubiquitinate target proteins
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000160 kyphosis "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Cnptm1(cre)Kan/Cnp+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0000358 abnormal cell content/ morphology "structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0000478 delayed intestine development "slowed progression to a structurally mature intestine" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Slc45a2uw/Slc45a2uw
Genetic Background: C57BL/6J-Slc45a2uw/J

 MP:0000528 delayed kidney development "late onset of the induction and/or differentiation of the kidney" [J:18048]
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Allelic Composition: Slc45a2uw/Slc45a2uw
Genetic Background: C57BL/6J-Slc45a2uw/J

 MP:0000598 abnormal liver morphology "malformation or absence of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:23170]
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Allelic Composition: Slc45a2uw/Slc45a2uw
Genetic Background: C57BL/6J-Slc45a2uw/J

Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0000599 enlarged liver "larger than average size of the liver" [J:65146]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Cnptm1(cre)Kan/Cnp+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0000747 muscle weakness "loss of muscle strength" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Slc45a2uw/Slc45a2uw
Genetic Background: C57BL/6J-Slc45a2uw/J

 MP:0000754 partial paralysis "partial loss of power of voluntary movement in a muscle through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Cnptm1(cre)Kan/Cnp+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0000788 abnormal cerebral cortex morphology "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]
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Allelic Composition: Slc45a2uw/Slc45a2uw
Genetic Background: C57BL/6J-Slc45a2uw/J

 MP:0000920 abnormal myelination "atypical or altered myelination in axon sheaths" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Cnptm1(cre)Kan/Cnp+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0000953 abnormal oligodendrocyte morphology "anomalous structure, number or composition of the neuroglia of the central nervous system that form the insulating myelin sheath of axons in the CNS" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Cnptm1(cre)Kan/Cnp+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Faslpr/Faslpr
Genetic Background: involves: MRL/Mp

 MP:0001154 seminiferous tubule degeneration "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Slc45a2uw/Slc45a2uw
Genetic Background: C57BL/6J-Slc45a2uw/J

Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Cnptm1(cre)Kan/Cnp+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001731 abnormal postnatal growth "anomaly in reaching a developmental stage or stages after birth" [il:Ira Lu, Mouse Genome Informatics Curator]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0001845 abnormal inflammatory response "aberrant reaction of the microcirculation characterized by movement of fluid and leukocytes from the blood into extravascular tissues" [Pathology:ISBN 0-397-51047-0]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Cnptm1(cre)Kan/Cnp+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001889 delayed brain development "the delay or slower progress of the growth and differentiation of the brain" [J:81818, il:Ira Lu , Mouse Genome Informatics Curator]
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Allelic Composition: Slc45a2uw/Slc45a2uw
Genetic Background: C57BL/6J-Slc45a2uw/J

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001951 abnormal breathing "irregular or atypical breathing pattern " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:17489]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Cnptm1(cre)Kan/Cnp+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001954 respiratory distress "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
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Allelic Composition: Slc45a2uw/Slc45a2uw
Genetic Background: C57BL/6J-Slc45a2uw/J

 MP:0002078 abnormal glucose homeostasis "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Slc45a2uw/Slc45a2uw
Genetic Background: C57BL/6J-Slc45a2uw/J

 MP:0002183 gliosis "increased growth pattern of neuroglia in a damaged area of the brain or spinal cord" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Cnptm1(cre)Kan/Cnp+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002216 abnormal seminiferous tubule morphology "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003634 abnormal glia "malformation or absence of non-neuronal cells of the nervous system that form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Cnptm1(cre)Kan/Cnp+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Slc45a2uw/Slc45a2uw
Genetic Background: C57BL/6J-Slc45a2uw/J

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0005058 abnormal lysosome morphology "anomalous structure of any of the cytoplasmic, membrane bound vesicles that contain a variety of hydrolases" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0005141 liver hyperplasia "increased size of liver due to increased hepatocyte cell number" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33827]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0005365 abnormal bile salt homeostasis "anomalous regulation of the steroid salts derived from cholesterol in the liver and which play an important role in the digestion and absorption of fats" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:86154]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0005404 abnormal axon morphology "anomaly in the structure of the single process of a nerve cell that normally conducts impulses away from the cell body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Cnptm1(cre)Kan/Cnp+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0008019 liver tumor "presence of abnormal, rapidly proliferating cells in the liver usually in the form of a distinct mass" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0008026 abnormal brain white matter morphology "any structural anomaly of the regions of the brain that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Cnptm1(cre)Kan/Cnp+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0008489 postnatal slow weight gain "the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0008918 microgliosis "a proliferation or spread of microglia in the area of a degenerative lesion or damaged tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Cnptm1(cre)Kan/Cnp+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0009378 abnormal endoplasmic reticulum morphology "any structural anomaly of irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells" [GO:0005783]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0009642 abnormal blood homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0010952 abnormal fatty acid beta-oxidation "anomaly in the process that results in the complete oxidation of a long-chain fatty acid, beginning with the addition of coenzyme A to a fatty acid, with successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)" [GO:0006635]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0010955 abnormal respiratory electron transport chain "anomaly in the process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient" [GO:0022904]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0010956 abnormal mitochondrial ATP synthesis coupled electron transport "anomaly in the transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane and mediated by multisubunit enzyme complexes known as complex I-IV" [GO:0042775, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Slc45a2uw/Slc45a2uw
Genetic Background: C57BL/6J-Slc45a2uw/J

 MP:0011633 abnormal mitochondrial shape "any anomaly in the characteristic surface outline or contour of a mitochondria" [MGI:csmith]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0011634 abnormal mitochondrial inner membrane morphology "any structural anomaly of the inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope, which is highly folded to form cristae" [GO:0005743]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0011635 abnormal mitochondrial crista morphology "Any of the inward folds of the mitochondrial inner membrane; crista number, extent, and shape differ in mitochondria from different tissues and organisms; crista appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found; the shape can vary with the respiratory state of the mitochondria" [GO:0030061]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0013405 increased circulating lactate level "greater amount of lactate in the blood which is produced from pyruvate by lactate dehydrogenase" [MPD:Molly]
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Allelic Composition: Pex5tm1Pec/Pex5tm1Pec,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002763 Pex6 / Q99LC9 / Peroxisome assembly factor 2 / Q13608* / peroxisomal biogenesis factor 6*  / complex / reaction
 ENSMUSG00000005907 Pex1 / Q5BL07 / Peroxisome biosis factor 1 / O43933* / peroxisomal biogenesis factor 1*  / complex / reaction
 ENSMUSG00000020283 Pex13 / Q9D0K1 / Peroxisomal membrane protein PEX13 / Q92968* / peroxisomal biogenesis factor 13*  / complex / reaction
 ENSMUSG00000019927 P61080 / Ube2d1 / ubiquitin-conjugating enzyme E2D 1 / P51668*  / complex / reaction
 ENSMUSG00000020003 Pex7 / P97865 / Peroxisomal targeting signal 2 receptor / O00628* / peroxisomal biogenesis factor 7*  / complex
 ENSMUSG00000018733 Pex12 / Q8VC48 / Peroxisome assembly protein 12 / O00623* / peroxisomal biogenesis factor 12*  / complex / reaction
 ENSMUSG00000010651 Acaa1b / Q8VCH0 / acetyl-Coenzyme A acyltransferase 1B / ACAA1* / P09110* / acetyl-CoA acyltransferase 1*  / complex
 ENSMUSG00000026664 Phyh / O35386 / phytanoyl-CoA hydroxylase / O14832* / phytanoyl-CoA 2-hydroxylase*  / complex
 ENSMUSG00000036138 Acaa1a / Q921H8 / acetyl-Coenzyme A acyltransferase 1A / ACAA1* / P09110* / acetyl-CoA acyltransferase 1*  / complex
 ENSMUSG00000028186 Uox / P25688 / urate oxidase  / complex / reaction
 ENSMUSG00000040374 Pex2 / peroxisomal biogenesis factor 2 / P28328*  / complex / reaction
 ENSMUSG00000020777 Acox1 / Q9R0H0 / Peroxisomal acyl-coenzyme A oxidase 1 / Q15067* / acyl-CoA oxidase 1*  / complex / reaction
 ENSMUSG00000030629 Q9DCH6 / Zfand6 / zinc finger, AN1-type domain 6 / Q6FIF0* / zinc finger AN1-type containing 6*  / complex / reaction
 ENSMUSG00000067825 Pex26 / Q8BGI5 / Peroxisome assembly protein 26 / Q7Z412* / peroxisomal biogenesis factor 26*  / complex / reaction
 ENSMUSG00000029047 Pex10 / B1AUE5 / Peroxisome biosis factor 10 / O60683* / peroxisomal biogenesis factor 10*  / complex / reaction
 ENSMUSG00000028975 Pex14 / Q9R0A0 / Peroxisomal membrane protein PEX14 / O75381* / peroxisomal biogenesis factor 14*  / complex / reaction
 ENSMUSG00000031010 Usp9x / ubiquitin specific peptidase 9, X chromosome / Q93008* / ubiquitin specific peptidase 9, X-linked*  / complex / reaction
 ENSMUSG00000078578 P61079 / Ube2d3 / ubiquitin-conjugating enzyme E2D 3 / P61077*  / complex / reaction
 ENSMUSG00000091896 P62838 / Ube2d2a / ubiquitin-conjugating enzyme E2D 2A / UBE2D2* / P62837* / ubiquitin conjugating enzyme E2 D2*  / complex / reaction






 

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