ENSMUSG00000018733


Mus musculus

Features
Gene ID: ENSMUSG00000018733
  
Biological name :Pex12
  
Synonyms : Peroxisome assembly protein 12 / Pex12 / Q8VC48
  
Possible biological names infered from orthology : O00623 / peroxisomal biogenesis factor 12
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: C
Gene start: 83294642
Gene end: 83302586
  
Corresponding Affymetrix probe sets: 10389164 (MoGene1.0st)   1416259_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118829
Ensembl peptide - ENSMUSP00000018877
Ensembl peptide - ENSMUSP00000103781
Ensembl peptide - ENSMUSP00000135632
Ensembl peptide - ENSMUSP00000134965
Ensembl peptide - ENSMUSP00000135145
NCBI entrez gene - 103737     See in Manteia.
MGI - MGI:2144177
RefSeq - NM_134025
RefSeq - XM_006531913
RefSeq - XM_006531914
RefSeq - XM_006531915
RefSeq Peptide - NP_598786
swissprot - Q5SWQ9
swissprot - Q5SWQ8
swissprot - H3BJF5
swissprot - Q8VC48
Ensembl - ENSMUSG00000018733
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pex12ENSDARG00000035149Danio rerio
 PEX12ENSGALG00000002151Gallus gallus
 PEX12ENSG00000108733Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006845  Pex, N-terminal
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017375  Peroxisome assembly protein 12


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006513 protein monoubiquitination IBA
 biological_processGO:0006625 protein targeting to peroxisome IEA
 biological_processGO:0007031 peroxisome organization ISO
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016558 protein import into peroxisome matrix ISO
 cellular_componentGO:0005777 peroxisome ISO
 cellular_componentGO:0005778 peroxisomal membrane IEA
 cellular_componentGO:0005779 integral component of peroxisomal membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:1990429 peroxisomal importomer complex IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0008022 protein C-terminus binding ISO
 molecular_functionGO:0008270 zinc ion binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
E3 ubiquitin ligases ubiquitinate target proteins
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002763 Pex6 / Q99LC9 / Peroxisome assembly factor 2 / Q13608* / peroxisomal biogenesis factor 6*  / complex / reaction
 ENSMUSG00000005907 Pex1 / Q5BL07 / Peroxisome biosis factor 1 / O43933* / peroxisomal biogenesis factor 1*  / complex / reaction
 ENSMUSG00000019927 P61080 / Ube2d1 / ubiquitin-conjugating enzyme E2D 1 / P51668*  / complex / reaction
 ENSMUSG00000020283 Pex13 / Q9D0K1 / Peroxisomal membrane protein PEX13 / Q92968* / peroxisomal biogenesis factor 13*  / complex
 ENSMUSG00000010651 Acaa1b / Q8VCH0 / acetyl-Coenzyme A acyltransferase 1B / ACAA1* / P09110* / acetyl-CoA acyltransferase 1*  / complex
 ENSMUSG00000020003 Pex7 / P97865 / Peroxisomal targeting signal 2 receptor / O00628* / peroxisomal biogenesis factor 7*  / complex
 ENSMUSG00000026664 Phyh / O35386 / phytanoyl-CoA hydroxylase / O14832* / phytanoyl-CoA 2-hydroxylase*  / complex
 ENSMUSG00000036138 Acaa1a / Q921H8 / acetyl-Coenzyme A acyltransferase 1A / ACAA1* / P09110* / acetyl-CoA acyltransferase 1*  / complex
 ENSMUSG00000005069 Pex5 / O09012 / Peroxisomal targeting signal 1 receptor / P50542* / peroxisomal biogenesis factor 5*  / complex / reaction
 ENSMUSG00000030629 Q9DCH6 / Zfand6 / zinc finger, AN1-type domain 6 / Q6FIF0* / zinc finger AN1-type containing 6*  / complex / reaction
 ENSMUSG00000067825 Pex26 / Q8BGI5 / Peroxisome assembly protein 26 / Q7Z412* / peroxisomal biogenesis factor 26*  / complex / reaction
 ENSMUSG00000028975 Pex14 / Q9R0A0 / Peroxisomal membrane protein PEX14 / O75381* / peroxisomal biogenesis factor 14*  / complex
 ENSMUSG00000040374 Pex2 / peroxisomal biogenesis factor 2 / P28328*  / complex
 ENSMUSG00000029047 Pex10 / B1AUE5 / Peroxisome biosis factor 10 / O60683* / peroxisomal biogenesis factor 10*  / complex
 ENSMUSG00000078578 P61079 / Ube2d3 / ubiquitin-conjugating enzyme E2D 3 / P61077*  / complex / reaction
 ENSMUSG00000091896 P62838 / Ube2d2a / ubiquitin-conjugating enzyme E2D 2A / UBE2D2* / P62837* / ubiquitin conjugating enzyme E2 D2*  / complex / reaction






 

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