ENSMUSG00000006058


Mus musculus

Features
Gene ID: ENSMUSG00000006058
  
Biological name :Snf8
  
Synonyms : Mus musculus SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) (Snf8), transcript variant 2, mRNA. / Q9CZ28 / Snf8
  
Possible biological names infered from orthology : Q96H20 / SNF8, ESCRT-II complex subunit
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: D
Gene start: 96034885
Gene end: 96047430
  
Corresponding Affymetrix probe sets: 10380591 (MoGene1.0st)   1432526_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000006217
Ensembl peptide - ENSMUSP00000103328
NCBI entrez gene - 27681     See in Manteia.
MGI - MGI:1343161
RefSeq - XM_017314573
RefSeq - NM_001356362
RefSeq - NM_033568
RefSeq - XM_006533467
RefSeq - XM_006533468
RefSeq Peptide - NP_001343291
RefSeq Peptide - NP_291046
swissprot - Q9CZ28
swissprot - A2A6M1
Ensembl - ENSMUSG00000006058
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snf8ENSDARG00000058076Danio rerio
 SNF8ENSGALG00000001309Gallus gallus
 SNF8ENSG00000159210Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR016689  ESCRT-2 complex, Snf8
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010797 regulation of multivesicular body size involved in endosome transport IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0032456 endocytic recycling IEA
 biological_processGO:0042176 regulation of protein catabolic process IEA
 biological_processGO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IEA
 biological_processGO:0045022 early endosome to late endosome transport IEA
 biological_processGO:0045732 positive regulation of protein catabolic process IEA
 biological_processGO:0061635 regulation of protein complex stability IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0071985 multivesicular body sorting pathway IEA
 biological_processGO:1903543 positive regulation of exosomal secretion IEA
 biological_processGO:1903772 regulation of viral budding via host ESCRT complex IEA
 cellular_componentGO:0000814 ESCRT II complex IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0031902 late endosome membrane ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0055037 recycling endosome IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0016247 channel regulator activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA


Pathways (from Reactome)
Pathway description
Endosomal Sorting Complex Required For Transport (ESCRT)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002702 decreased circulating free fatty acid level "lower than normal levels of unesterified fatty acids in the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1+
Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000078656 Vps25 / Q9CQ80 / vacuolar protein sorting 25 / Q9BRG1* / vacuolar protein sorting 25 homolog*  / complex
 ENSMUSG00000014402 Q61187 / Tsg101 / tumor susceptibility gene 101 / Q99816* / tumor susceptibility 101*  / reaction
 ENSMUSG00000066278 Q8R0J7 / Vps37b / vacuolar protein sorting 37B / Q9H9H4* / VPS37B, ESCRT-I subunit*  / reaction
 ENSMUSG00000031813 Mvb12a / Q78HU3 / Multivesicular body subunit 12A / Q96EY5*  / reaction
 ENSMUSG00000031479 Vps36 / Q91XD6 / vacuolar protein sorting 36 / Q86VN1* / vacuolar protein sorting 36 homolog*  / complex
 ENSMUSG00000038740 Mvb12b / Q6KAU4 / Multivesicular body subunit 12B / Q9H7P6*  / reaction
 ENSMUSG00000043614 Q810I0 / Vps37d / vacuolar protein sorting 37D / Q86XT2* / VPS37D, ESCRT-I subunit*  / reaction
 ENSMUSG00000028437 Ubap1 / Q8BH48 / ubiquitin-associated protein 1 / Q9NZ09*  / reaction
 ENSMUSG00000048832 Q8R105 / Vps37c / vacuolar protein sorting 37C / A5D8V6* / VPS37C, ESCRT-I subunit*  / reaction
 ENSMUSG00000115987 Vps28 / Q9D1C8 / vacuolar protein sorting 28 / Q9UK41* / VPS28, ESCRT-I subunit*  / reaction
 ENSMUSG00000031600 Q8CHS8 / Vps37a / vacuolar protein sorting 37A / Q8NEZ2* / VPS37A, ESCRT-I subunit*  / reaction






 

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