ENSMUSG00000031600


Mus musculus

Features
Gene ID: ENSMUSG00000031600
  
Biological name :Vps37a
  
Synonyms : Q8CHS8 / vacuolar protein sorting 37A / Vps37a
  
Possible biological names infered from orthology : Q8NEZ2 / VPS37A, ESCRT-I subunit
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: A4
Gene start: 40511783
Gene end: 40551134
  
Corresponding Affymetrix probe sets: 10571415 (MoGene1.0st)   1419176_at (Mouse Genome 430 2.0 Array)   1419177_at (Mouse Genome 430 2.0 Array)   1429363_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000096415
NCBI entrez gene - 52348     See in Manteia.
MGI - MGI:1261835
RefSeq - NM_033560
RefSeq - XM_011242230
RefSeq Peptide - NP_291038
swissprot - Q8CHS8
Ensembl - ENSMUSG00000031600
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vps37aENSDARG00000017119Danio rerio
 VPS37AENSGALG00000013646Gallus gallus
 Q8NEZ2ENSG00000155975Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q810I0 / Vps37d / vacuolar protein sorting 37D / Q86XT2* / VPS37D, ESCRT-I subunit*ENSMUSG0000004361411
Q8R105 / Vps37c / vacuolar protein sorting 37C / A5D8V6* / VPS37C, ESCRT-I subunit*ENSMUSG0000004883211
Q8R0J7 / Vps37b / vacuolar protein sorting 37B / Q9H9H4* / VPS37B, ESCRT-I subunit*ENSMUSG0000006627811


Protein motifs (from Interpro)
Interpro ID Name
 IPR009851  Modifier of rudimentary, Modr
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR037202  ESCRT assembly domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0032509 endosome transport via multivesicular body sorting pathway IEA
 biological_processGO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IEA
 cellular_componentGO:0000813 ESCRT I complex ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Endosomal Sorting Complex Required For Transport (ESCRT)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000014402 Q61187 / Tsg101 / tumor susceptibility gene 101 / Q99816* / tumor susceptibility 101*  / complex
 ENSMUSG00000031813 Mvb12a / Q78HU3 / Multivesicular body subunit 12A / Q96EY5*  / complex
 ENSMUSG00000038740 Mvb12b / Q6KAU4 / Multivesicular body subunit 12B / Q9H7P6*  / complex
 ENSMUSG00000028437 Ubap1 / Q8BH48 / ubiquitin-associated protein 1 / Q9NZ09*  / complex
 ENSMUSG00000006058 Snf8 / Q9CZ28 / Mus musculus SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) (Snf8), transcript variant 2, mRNA. / Q96H20* / SNF8, ESCRT-II complex subunit*  / reaction
 ENSMUSG00000078656 Vps25 / Q9CQ80 / vacuolar protein sorting 25 / Q9BRG1* / vacuolar protein sorting 25 homolog*  / reaction
 ENSMUSG00000026718 Stam / P70297 / signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 / Q92783* / signal transducing adaptor molecule*  / reaction
 ENSMUSG00000031479 Vps36 / Q91XD6 / vacuolar protein sorting 36 / Q86VN1* / vacuolar protein sorting 36 homolog*  / reaction
 ENSMUSG00000115987 Vps28 / Q9D1C8 / vacuolar protein sorting 28 / Q9UK41* / VPS28, ESCRT-I subunit*  / complex
 ENSMUSG00000055371 Stam2 / O88811 / signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 / O75886* / signal transducing adaptor molecule 2*  / reaction






 

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