Manteia

ENSMUSG00000066278

Mus musculus

Features

Gene ID:	ENSMUSG00000066278

Biological name :	Vps37b

Synonyms :	Q8R0J7 / vacuolar protein sorting 37B / Vps37b

Possible biological names infered from orthology :	Q9H9H4 / VPS37B, ESCRT-I subunit

Species:	Mus musculus

Chr. number:	5
Strand:	-1
Band:	F
Gene start:	124004641
Gene end:	124032270

Corresponding Affymetrix probe sets:	10533729 (MoGene1.0st) 1424380_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000047980 NCBI entrez gene - 330192 See in Manteia. MGI - MGI:1916724 RefSeq - NM_177876 RefSeq Peptide - NP_808544 swissprot - Q8R0J7 Ensembl - ENSMUSG00000066278

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Q8R105 / Vps37c / vacuolar protein sorting 37C / A5D8V6* / VPS37C, ESCRT-I subunit*	ENSMUSG00000048832	37
Q810I0 / Vps37d / vacuolar protein sorting 37D / Q86XT2* / VPS37D, ESCRT-I subunit*	ENSMUSG00000043614	28
Q8CHS8 / Vps37a / vacuolar protein sorting 37A / Q8NEZ2* / VPS37A, ESCRT-I subunit*	ENSMUSG00000031600	15

Protein motifs (from Interpro)

Interpro ID	Name
IPR009851	Modifier of rudimentary, Modr
IPR037202	ESCRT assembly domain

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0015031	protein transport	IEA
biological_process	GO:0032509	endosome transport via multivesicular body sorting pathway	IEA
biological_process	GO:1902188	positive regulation of viral release from host cell	IEA
biological_process	GO:1903774	positive regulation of viral budding via host ESCRT complex	IEA
cellular_component	GO:0000813	ESCRT I complex	ISO
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005768	endosome	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0010008	endosome membrane	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0030496	midbody	IEA
cellular_component	GO:0031902	late endosome membrane	IEA
molecular_function	GO:0048306	calcium-dependent protein binding	IEA

Pathways (from Reactome)

Pathway description

Endosomal Sorting Complex Required For Transport (ESCRT)

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000014402	Q61187 / Tsg101 / tumor susceptibility gene 101 / Q99816* / tumor susceptibility 101*	/ complex
ENSMUSG00000006058	Snf8 / Q9CZ28 / Mus musculus SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) (Snf8), transcript variant 2, mRNA. / Q96H20* / SNF8, ESCRT-II complex subunit*	/ reaction
ENSMUSG00000078656	Vps25 / Q9CQ80 / vacuolar protein sorting 25 / Q9BRG1* / vacuolar protein sorting 25 homolog*	/ reaction
ENSMUSG00000026718	Stam / P70297 / signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 / Q92783* / signal transducing adaptor molecule*	/ reaction
ENSMUSG00000031479	Vps36 / Q91XD6 / vacuolar protein sorting 36 / Q86VN1* / vacuolar protein sorting 36 homolog*	/ reaction
ENSMUSG00000115987	Vps28 / Q9D1C8 / vacuolar protein sorting 28 / Q9UK41* / VPS28, ESCRT-I subunit*	/ complex
ENSMUSG00000055371	Stam2 / O88811 / signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 / O75886* / signal transducing adaptor molecule 2*	/ reaction
ENSMUSG00000031813	Mvb12a / Q78HU3 / Multivesicular body subunit 12A / Q96EY5*	/ complex
ENSMUSG00000038740	Mvb12b / Q6KAU4 / Multivesicular body subunit 12B / Q9H7P6*	/ complex
ENSMUSG00000028437	Ubap1 / Q8BH48 / ubiquitin-associated protein 1 / Q9NZ09*	/ complex

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr